Last update :
21/02/2024
Anxiolytic   Lorazepam  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Ativan Great Britain, United States of America
Tavor Italy
Temesta Austria, Belgium, France, Netherlands, Switzerland
Compatibility   Injection   Compatibility : Lorazepam              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Lorazepam 0.04 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Immediate precipitation Incompatible
Injection Lorazepam 2 mg/ml
Injection Aldesleukin 0.0338 MUI/ml
Glucose 5% 36
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Amikacin sulfate 5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 1 mg/ml
Injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Amoxicillin sodium 50 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 4 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Amoxicillin sodium / clavulanic acid 20/2 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Amsacrine 1 mg/ml
Glucose 5% 253
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Atracurium besylate 0.5 mg/ml
Glucose 5% 402
Turbidity in one hour Incompatible
Injection Lorazepam 0.1 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Immediate precipitation Incompatible
Injection Lorazepam 0.8 & 1.33 mg/ml
Injection Benztropine mesylate 0.67 & 0.8 mg/ml
None 1724
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Bivalirudin
3539
Unspecified incompatibility Incompatible
Injection Lorazepam 2 mg/ml
Injection Bivalirudin
3539
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Bumetanide 0.5 mg/ml
Sodium chloride 0,9% 186
Immediate precipitation Incompatible
Injection Lorazepam 4 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Lorazepam 0,5 mg/ml
Injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Immediate precipitation Incompatible
Injection Lorazepam 1 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
Injection Lorazepam 4 mg/ml
Injection Cefmetazole sodium 100 mg/ml
Water for Injection 93
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Cefotaxime sodium 10 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0,5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Compatible
Injection Lorazepam 0,5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
Injection Lorazepam 1 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Immediate precipitation Incompatible
Injection Lorazepam 0.44 & 0.8 mg/ml
Injection Chlorpromazine hydrochloride 20 & 22.22 mg/ml
None 1724
Compatible
Injection Lorazepam 2 mg/ml
Injection Cimetidine hydrochloride 150 mg/ml
1438
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Clonidine hydrochloride 0.015 mg/ml
Sodium chloride 0,9% 186
Turbidity in 4 hours Incompatible
Injection Lorazepam 4 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Co-trimoxazole 0.8/4 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Dexamethasone sodium phosphate 4 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Lorazepam 4 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Diltiazem hydrochloride 1 mg/ml
314
Compatible
Injection Lorazepam 2 mg/ml
Injection Diltiazem hydrochloride 1 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Lorazepam
Injection Dimenhydrinate
2087
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Dobutamine hydrochloride 4 mg/ml
314
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Dopamine hydrochloride 3.2 mg/ml
314
Compatible
Injection Lorazepam 0,5 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Epinephrine hydrochloride 20 µg/ml
314
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Erythromycin lactobionate 5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 2 mg/ml
Injection Etomidate 2 mg/ml
None 319
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Fentanyl citrate 25 µg/ml
Glucose 5% 1974
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Fentanyl citrate 50 µg/ml
314
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Fentanyl citrate 50 µg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Turbidity in 4 hours Incompatible
Injection Lorazepam 0.33 mg/ml
Injection Flucloxacillin sodium 50 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.1 mg/ml
Parenteral nutrition (binary mixture) 301
Immediate precipitation Incompatible
Injection Lorazepam 4 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
Injection Lorazepam 0,08 mg/ml
Injection Foscarnet sodium 24 mg/ml
NaCl 0,9% or Glucose 5% 1135
Instability of the emulsion after 1 hour Incompatible
Injection Lorazepam 0.1 mg/ml
Parenteral nutrition (with lipids) 1415
Production of gas bubbles Incompatible
Injection Lorazepam 4 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Compatible
Injection Lorazepam 1 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Compatible
Injection Lorazepam 1 mg/ml
Injection Fosphenytoin sodium 5 mg/ml
Sodium chloride 0,9% 1419
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Furosemide 10 mg/ml
314
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Furosemide 10 mg/ml
Sodium chloride 0,9% 186
Immediate precipitation Incompatible
Injection Lorazepam 1 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Gentamicin sulfate 3 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam
Injection Glycopyrronium bromide
3599
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Granisetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 57
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Haloperidol lactate 0.5 & 5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Heparin sodium 417 UI/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Heparin sodium 100 UI/ml
314
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Human albumin 200 mg/ml
Sodium chloride 0,9% 186
Unspecified incompatibility Incompatible
Injection Lorazepam
Injection Hyaluronidase
3617
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Hydrocortisone sodium succinate 50 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Hydromorphone hydrochloride 1 mg/ml
314
Compatible
Injection Lorazepam 4 mg/ml
Injection Hydromorphone hydrochloride 2 >> 40 mg/ml
None 1497
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 1974
Color change Incompatible
Injection Lorazepam 2 mg/ml
Injection Idarubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Precipitation after 24 hours Incompatible
Injection Lorazepam 0.33 mg/ml
Injection Imipenem - cilastatin sodium 5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 1 mg/ml
Injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Compatible
Injection Lorazepam 4 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
4389
Immediate turbidity Incompatible
Injection Lorazepam 4 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Labetalol hydrochloride 2 mg/ml
314
Immediate precipitation Incompatible
Injection Lorazepam 0.5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Lorazepam 2 mg/ml
Injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Precipitation after 15 minutes Incompatible
Injection Lorazepam 1.33 >> 2.67 mg/ml
Injection Loxapine 16.67 >> 33.3 mg/ml
None 1724
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Methadone hydrochloride 1 mg/ml
Glucose 5% 1974
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Metronidazole 5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Midazolam hydrochloride 2 mg/ml
314
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Milrinone lactate 0.2 mg/ml
314
Compatible
Injection Lorazepam 0.4 mg/ml
Injection Milrinone lactate 0.8 mg/ml
Glucose 5% 813
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Morphine hydrochloride 1 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Morphine sulfate 2 mg/ml
314
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Precipitation after 15 minutes Incompatible
Injection Lorazepam 4 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Nicardipine hydrochloride 1 mg/ml
314
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Nitroglycerin 0.4 mg/ml
314
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Norepinephrine bitartrate 0.128 mg/ml
314
Color change Incompatible
Injection Lorazepam 0.33 mg/ml
Injection Omeprazole sodium 4 mg/ml
Sodium chloride 0,9% 186
Immediate turbidity Incompatible
Injection Lorazepam 0.1 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
Injection Lorazepam 1 mg/ml
Injection Oritavancin 0.8 >>2 mg/ml
Glucose 5% 3152
Compatible
Injection Lorazepam 0,5 mg/ml
Injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Paclitaxel 1.2 mg/ml
Glucose 5% 85
Compatible
Injection Lorazepam 0,5 mg/ml
Injection Palonosetron hydrochloride 50 µg/ml
Glucose 5% 1975
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Pancuronium bromide 0.05 mg/ml
Glucose 5% 402
Immediate precipitation Incompatible
Injection Lorazepam
Injection Pantoprazole sodium
2090
Turbidity in 4 hours Incompatible
Injection Lorazepam 4 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Piperacillin sodium 150 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Lorazepam 1 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
Injection Lorazepam
Injection Posaconazole
4380
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Potassium chloride 1000 mEq/l
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 2 mg/ml
Injection Propofol 2 mg/ml
None 319
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Lorazepam 4 mg/ml
Injection Ranitidine hydrochloride 25 mg/ml
None 58
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Ranitidine hydrochloride 1 mg/ml
314
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Ranitidine hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Immediate precipitation Incompatible
Injection Lorazepam 4 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Turbidity in one hour Incompatible
Injection Lorazepam 0.1 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Lorazepam 1 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Lorazepam 1 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Lorazepam 4 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Color change Incompatible
Injection Lorazepam 2 mg/ml
Injection Thiopental sodium 25 mg/ml
Water for Injection 319
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Thiopental sodium 25 mg/ml
314
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
Injection Lorazepam 1 mg/ml
Injection Valproic acid 2 & 20 mg/ml
NaCl 0,9% or Glucose 5% 4428
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Vancomycin hydrochloride 5 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Vecuronium bromide 0.1 mg/ml
Glucose 5% 402
Compatible
Injection Lorazepam 0.5 mg/ml
Injection Vecuronium bromide 1 mg/ml
314
Compatible
Injection Lorazepam 0.33 mg/ml
Injection Vecuronium bromide 4 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Lorazepam 0.1 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
Injection Lorazepam 0.08 mg/ml
Injection Zidovudine 4 mg/ml
Glucose 5% 337

  Mentions Légales