Last update :
10/07/2024
Analgesic   Morphine sulfate  
injection
Ointments Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Dimor F Brazil
Duramorph United States of America
Infumorph United States of America
Miniject Morphine Great Britain
Morphine Canada
Morphine sulfate Lavoisier France
Stability in solutions   injection   Stability in solutions : Morphine sulfate     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 2 & 15 mg/ml 23°C-25°C Not specified
12 Day
65
Level of evidence B

Glass Water for Injection 2 & 15 mg/ml 4°C Protect from light
12 Day
65
Level of evidence B

Glass NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 23°C With or without light
7 Day
117
Level of evidence C

Glass NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 4°C Protect from light
7 Day
117
Level of evidence C

Glass Sodium chloride 0,9% 0,2 mg/ml 14-22°C Protect from light
336 Day
1341
Level of evidence B

Glass NaCl 0,9% + antibacterial 1 mg/ml 22°C Protect from light
91 Day
115
Level of evidence C

Glass NaCl 0,9% + antibacterial 1 mg/ml 4°C Protect from light
91 Day
115
Level of evidence C

Glass Not specified 50 mg/ml 37°C Protect from light
90 Day
2305

Polyvinyl chloride Water for Injection 2 & 15 mg/ml 23°C-25°C Not specified
12 Day
65
Level of evidence B

Polyvinyl chloride Water for Injection 2 & 15 mg/ml 4°C Protect from light
12 Day
65
Level of evidence B

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 23°C With or without light
7 Day
117
Level of evidence C

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,04 & 0,4 mg/ml 4°C Protect from light
7 Day
117
Level of evidence C

Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 23°C Not specified
30 Day
120
Level of evidence C

Polyvinyl chloride Sodium chloride 0,9% 1 & 10 mg/ml 32°C Protect from light
16 Day
932
Level of evidence A

Polyvinyl chloride Sodium chloride 0,9% 1>> 25 mg/ml 25°C Protect from light
14 Day
116
Level of evidence A

Polyvinyl chloride Sodium chloride 0,9% 1>> 25 mg/ml 37°C Protect from light
3 Day
116
Level of evidence A

Polyvinyl chloride Sodium chloride 0,9% 1>> 25 mg/ml 5°C Protect from light
30 Day
116
Level of evidence A

Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 23°C Not specified
31 Day
121
Level of evidence B

Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 4°C Not specified
31 Day
121
Level of evidence B

Polyvinyl chloride Glucose 5% 1,2 mg/ml 21°C Light
36 Hour
340
Level of evidence A

Polyvinyl chloride Glucose 5% 10 mg/ml 23°C Not specified
31 Day
121
Level of evidence B

Polyvinyl chloride Glucose 5% 10 mg/ml 4°C Protect from light
31 Day
121
Level of evidence B

Polyvinyl chloride None 10 mg/ml 23°C Light
30 Day
120
Level of evidence C

Polyvinyl chloride None 25 & 50 mg/ml 23°C Not specified
31 Day
121
Level of evidence B

Polyvinyl chloride None 25 & 50 mg/ml 4°C Protect from light
31 Day
121
Level of evidence B

Polypropylene Sodium chloride 0,9% 1 mg/ml 25°C Not specified
1095 Day
2064
Level of evidence A+

Polypropylen Syringe Water for Injection 50 mg/ml 23°C Protect from light
60 Day
1709
Level of evidence A+

Polypropylen Syringe Water for Injection 50 mg/ml 37°C Protect from light
48 Hour
1709
Level of evidence A+

Polypropylen Syringe NaCl 0,9% or Glucose 5% 1 mg/ml 25°C Not specified
100 Day
4303
Level of evidence A

Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 25°C Not specified
91 Day
4395
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 0,2 mg/ml 25°C Not specified
91 Day
4395
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 1,0 mg/ml 25°C Not specified
91 Day
4395
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 1,76 mg/ml 20°C-25°C Light
14 Day
1968
Level of evidence D

Polypropylen Syringe Sodium chloride 0,9% 2 mg/ml 25°C Protect from light
42 Day
122

Polypropylen Syringe Sodium chloride 0,9% 5 mg/ml 4°C Protect from light
60 Day
1709
Level of evidence A+

Polypropylen Syringe Sodium chloride 0,9% 5 & 50 mg/ml 23°C Light
60 Day
1709
Level of evidence A+

Polypropylen Syringe Sodium chloride 0,9% 5 & 50 mg/ml 37°C Protect from light
48 Hour
1709
Level of evidence A+

Polypropylen Syringe Glucose 5% 0,02 mg/ml 25°C Not specified
91 Day
4395
Level of evidence B

Polypropylen Syringe Glucose 5% 0,04 mg/ml 25°C Not specified
91 Day
4395
Level of evidence B

Polyisoprene elastomer Water for Injection 2 & 15 mg/ml 23°C-25°C Not specified
12 Day
65
Level of evidence B

Polyisoprene elastomer Water for Injection 2 & 15 mg/ml 31°C Not specified
12 Day
65
Level of evidence B

Polyisoprene elastomer Water for Injection 2 & 15 mg/ml 4°C Protect from light
12 Day
65
Level of evidence B

Polyisoprene elastomer None 2 & 10 mg/ml 22°C Not specified
40 Day
1810
Level of evidence D

Polyisoprene elastomer None 2 & 10 mg/ml 4°C Not specified
40 Day
1810
Level of evidence D

Not specified Sodium chloride 0,9% 2 & 3 mg/ml 25°C Not specified
60 Day
2123
Level of evidence A

Not specified Sodium chloride 0,9% 2 & 3 mg/ml 4°C Not specified
60 Day
2123
Level of evidence A


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