Last update :
27/11/2024
Anticancer drug   Pemetrexed disodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Alimta Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, Denmark, Ecuador, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Ireland, Italy, Japan, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, New Zealand, Norway, Peru, Poland, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates, United States of America, Venezuela
Alltrexed Argentina
Amtiris Switzerland
Armisarte
Ekel Argentina
Enzastar Argentina
Holista Argentina
Lidoras Argentina, Ecuador
Martxel Argentina
Pamifect India
Pemetrexed Argentina, Peru, Romania, Switzerland
Pemtrex Turkey
Peymetrel Argentina
Praxed Argentina
Prexed Turkey
Sukuba Argentina
Trexam Argentina
Trextech Argentina
Trixid Romania
Utrexed Argentina
Venusted Argentina
Stability in solutions   injection   Stability in solutions : Pemetrexed disodium     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 25 mg/ml 2-8°C Protect from light
28 Day
2183
Level of evidence A

Glass Sodium chloride 0,9% 25 mg/ml 2-8°C Not specified
24 Hour
1914
Manufacturer's stability data

Glass Sodium chloride 0,9% 25 mg/ml 2-8°C Protect from light
14 Day
4578
Level of evidence A

Glass Sodium chloride 0,9% 25 mg/ml 22°C Protect from light
14 Day
4578
Level of evidence A

Polyvinyl chloride NaCl 0,9% or Glucose 5% 2&10&20 mg/ml 23°C With or without light
24 Hour
2114
Level of evidence A+

Polyvinyl chloride NaCl 0,9% or Glucose 5% 2&10&20 mg/ml 4°C Protect from light
24 Hour
2114
Level of evidence A+

Polyethylene NaCl 0,9% or Glucose 5% 12,5 mg/ml 2-8°C Protect from light
14 Day
4137
Level of evidence A+

Polyethylene NaCl 0,9% or Glucose 5% 12,5 mg/ml 25°C Protect from light
2 Day
4137
Level of evidence A+

Polyethylene NaCl 0,9% or Glucose 5% 2,5 mg/ml 2-8°C Protect from light
14 Day
4137
Level of evidence A+

Polyethylene NaCl 0,9% or Glucose 5% 2,5 mg/ml 25°C Protect from light
2 Day
4137
Level of evidence A+

Polyethylene NaCl 0,9% or Glucose 5% 7,5 mg/ml 2-8°C Protect from light
14 Day
4137
Level of evidence A+

Polyethylene NaCl 0,9% or Glucose 5% 7,5 mg/ml 25°C Protect from light
2 Day
4137
Level of evidence A+

Polyolefine NaCl 0,9% or Glucose 5% 12,5 mg/ml 2-8°C Protect from light
14 Day
4137
Level of evidence A+

Polyolefine NaCl 0,9% or Glucose 5% 12,5 mg/ml 25°C Protect from light
2 Day
4137
Level of evidence A+

Polyolefine NaCl 0,9% or Glucose 5% 2,5 mg/ml 2-8°C Protect from light
14 Day
4137
Level of evidence A+

Polyolefine NaCl 0,9% or Glucose 5% 2,5 mg/ml 25°C Protect from light
2 Day
4137
Level of evidence A+

Polyolefine NaCl 0,9% or Glucose 5% 7,5 mg/ml 2-8°C Protect from light
14 Day
4137
Level of evidence A+

Polyolefine NaCl 0,9% or Glucose 5% 7,5 mg/ml 25°C Protect from light
2 Day
4137
Level of evidence A+

Polyolefine Sodium chloride 0,9% 2 & 13,5 mg/ml 2-8°C Protect from light
21 Day
4624
Level of evidence A+

Polypropylen Syringe Sodium chloride 0,9% 25 mg/ml 23°C With or without light
2 Day
2036
Level of evidence A+

Polypropylen Syringe Sodium chloride 0,9% 25 mg/ml 4°C Protect from light
31 Day
2036
Level of evidence A+


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