Bibliographie - 198 - Stabilis 4.0

Dernière mise à jour :
02/04/2025

Bibliographie 198

Type :

Revue

Equipes de recherche :

Kansas City - Marion Merrell Dow

Auteurs :

Gayed AA, Kheshary PR, Hinkle RL.

Titre :

Visual compatibility of diltiazem injection with various diluents and medications during simulated Y-site injection.

Référence :

Am J Health-Syst Pharm ; 52: 516-520. 1995

Niveau de preuve :

Stabilité physique :

Stabilité chimique :

Autres méthodes :

Commentaires :

Non coté : étude de compatibilité seule

Liste des molécules

Acetazolamide

	100 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	100 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+

Aciclovir sodium

5 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
7 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
5 & 7 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+

Amikacin sulfate

5 & 250 mg/ml

Diltiazem hydrochloride

5 mg/ml

Aminophylline

25 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
2 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
25 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+

Amphotericin B

0.1 mg/ml

Diltiazem hydrochloride

1 mg/ml

Ampicillin sodium

100 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
100 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
10 & 20 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Ampicillin sodium - sulbactam sodium

45 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
45 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
2 & 15 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Aztreonam

	333 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
	20 & 333 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Bretylium tosilate

	50 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
	10 & 50 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Bumetanide

0.25 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Cefamandole nafate

	10 >> 200 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	10 >> 200 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+

Cefazolin sodium

	200 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
	20 & 200 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Cefoperazone sodium

10 >> 50 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
10 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
20 >> 50 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
2 & 5 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Cefotaxime sodium

10 & 180 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Cefoxitin sodium

	200 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	10 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Ceftazidime

	170 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	10 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Ceftriaxone disodium

40 mg/ml

Diltiazem hydrochloride

5 mg/ml

Cefuroxime sodium

	100 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	15 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Cimetidine hydrochloride

	150 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	6 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Ciprofloxacin lactate

2 & 10 mg/ml

Diltiazem hydrochloride

5 mg/ml

Clindamycin phosphate

12 & 150 mg/ml

Diltiazem hydrochloride

5 mg/ml

Co-trimoxazole

0.21 & 0.63 mg/ml

Diltiazem hydrochloride

5 mg/ml

Diazepam

5 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Digoxin

500 µg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Diltiazem hydrochloride


5 mg/ml	+ Acetazolamide	100 mg/ml	+
1 mg/ml	+ Acetazolamide	100 mg/ml	+
5 mg/ml	+ Aciclovir sodium	5 mg/ml	+
1 mg/ml	+ Aciclovir sodium	5 & 7 mg/ml	+
5 mg/ml	+ Aciclovir sodium	7 mg/ml	+
5 mg/ml	+ Amikacin sulfate	5 & 250 mg/ml	+
1 mg/ml	+ Aminophylline	25 mg/ml	+
5 mg/ml	+ Aminophylline	2 mg/ml	+
5 mg/ml	+ Aminophylline	25 mg/ml	+
1 mg/ml	+ Amphotericin B	0.1 mg/ml	+
1 mg/ml	+ Ampicillin sodium	100 mg/ml	+
5 mg/ml	+ Ampicillin sodium	10 & 20 mg/ml	+
5 mg/ml	+ Ampicillin sodium	100 mg/ml	+
5 mg/ml	+ Ampicillin sodium - sulbactam sodium	45 mg/ml	+
1 mg/ml	+ Ampicillin sodium - sulbactam sodium	45 mg/ml	+
5 mg/ml	+ Ampicillin sodium - sulbactam sodium	2 & 15 mg/ml	+
1 mg/ml	+ Aztreonam	333 mg/ml	+
5 mg/ml	+ Aztreonam	20 & 333 mg/ml	+
5 mg/ml	+ Bretylium tosilate	10 & 50 mg/ml	+
1 mg/ml	+ Bretylium tosilate	50 mg/ml	+
1 & 5 mg/ml	+ Bumetanide	0.25 mg/ml	+
1 mg/ml	+ Cefamandole nafate	10 >> 200 mg/ml	+
5 mg/ml	+ Cefamandole nafate	10 >> 200 mg/ml	+
1 mg/ml	+ Cefazolin sodium	200 mg/ml	+
5 mg/ml	+ Cefazolin sodium	20 & 200 mg/ml	+
1 mg/ml	+ Cefoperazone sodium	10 mg/ml	+
1 & 5 mg/ml	+ Cefoperazone sodium	2 & 5 mg/ml	+
1 mg/ml	+ Cefoperazone sodium	20 >> 50 mg/ml	+
5 mg/ml	+ Cefoperazone sodium	10 >> 50 mg/ml	+
1 & 5 mg/ml	+ Cefotaxime sodium	10 & 180 mg/ml	+
5 mg/ml	+ Cefoxitin sodium	10 mg/ml	+
1 & 5 mg/ml	+ Cefoxitin sodium	200 mg/ml	+
1 & 5 mg/ml	+ Ceftazidime	170 mg/ml	+
5 mg/ml	+ Ceftazidime	10 mg/ml	+
5 mg/ml	+ Ceftriaxone disodium	40 mg/ml	+
1 & 5 mg/ml	+ Cefuroxime sodium	100 mg/ml	+
5 mg/ml	+ Cefuroxime sodium	15 mg/ml	+
5 mg/ml	+ Cimetidine hydrochloride	6 mg/ml	+
1 & 5 mg/ml	+ Cimetidine hydrochloride	150 mg/ml	+
5 mg/ml	+ Ciprofloxacin lactate	2 & 10 mg/ml	+
5 mg/ml	+ Clindamycin phosphate	12 & 150 mg/ml	+
5 mg/ml	+ Co-trimoxazole	0.21 & 0.63 mg/ml	+
1 & 5 mg/ml	+ Diazepam	5 mg/ml	+
1 & 5 mg/ml	+ Digoxin	500 µg/ml	+
1 & 5 mg/ml	+ Dobutamine hydrochloride	1 mg/ml	+
1 & 5 mg/ml	+ Dopamine hydrochloride	0.8 mg/ml	+
5 mg/ml	+ Doxycycline hyclate	1 & 10 mg/ml	+
1 & 5 mg/ml	+ Epinephrine hydrochloride	50 µg/ml	+
5 mg/ml	+ Epinephrine hydrochloride	4 µg/ml	+
5 mg/ml	+ Erythromycin lactobionate	5 & 50 mg/ml	+
5 mg/ml	+ Fluconazole	2 mg/ml	+
1 & 5 mg/ml	+ Furosemide	10 mg/ml	+
5 mg/ml	+ Gentamicin sulfate	2.4 & 40 mg/ml	+
1 & 5 mg/ml	+ Heparin sodium	80 >> 10000 UI/ml	+
5 mg/ml	+ Heparin sodium	20000 UI/ml	+
1 mg/ml	+ Heparin sodium	20000 UI/ml	+
5 mg/ml	+ Hetastarch	60 mg/ml	+
5 mg/ml	+ Human albumin	50 mg/ml	+
5 mg/ml	+ Human albumin	250 mg/ml	+
5 mg/ml	+ Hydrocortisone sodium succinate	50 & 125 mg/ml	+
1 mg/ml	+ Hydrocortisone sodium succinate	50 & 125 mg/ml	+
5 mg/ml	+ Hydrocortisone sodium succinate	1 & 2 mg/ml	+
5 mg/ml	+ Imipenem - cilastatin sodium	5 mg/ml	+
5 mg/ml	+ Insulin	0.4 UI/ml	+
1 & 5 mg/ml	+ Insulin	100 UI/ml	+
5 mg/ml	+ Lidocaine hydrochloride	4 & 8 mg/ml	+
1 & 5 mg/ml	+ Lidocaine hydrochloride	10 mg/ml	+
1 mg/ml	+ Lorazepam	2 mg/ml	+
5 mg/ml	+ Lorazepam	4 mg/ml	+
1 mg/ml	+ Methylprednisolone sodium succinate	2.5 >> 62.5 mg/ml	+
5 mg/ml	+ Methylprednisolone sodium succinate	2.5 >> 62.5 mg/ml	+
1 & 5 mg/ml	+ Metoclopramide hydrochloride	5 mg/ml	+
5 mg/ml	+ Metoclopramide hydrochloride	0.2 mg/ml	+
5 mg/ml	+ Metronidazole	5 & 8 mg/ml	+
1 & 5 mg/ml	+ Morphine sulfate	15 mg/ml	+
5 mg/ml	+ Morphine sulfate	0.4 mg/ml	+
5 mg/ml	+ Nafcillin sodium	10 & 200 mg/ml	+
1 mg/ml	+ Nafcillin sodium	10 & 200 mg/ml	+
1 & 5 mg/ml	+ Nitroglycerin	0.4 mg/ml	+
1 & 5 mg/ml	+ Nitroprusside sodium	0.2 mg/ml	+
1 & 5 mg/ml	+ Oxacillin sodium	100 mg/ml	+
5 mg/ml	+ Oxacillin sodium	10 mg/ml	+
1 & 5 mg/ml	+ Penicillin G potassium	1 MUI/ml	+
5 mg/ml	+ Penicillin G potassium	0.1 MUI/ml	+
5 mg/ml	+ Pentamidine isetionate	6 & 30 mg/ml	+
1 & 5 mg/ml	+ Pethidine hydrochloride	100 mg/ml	+
5 mg/ml	+ Pethidine hydrochloride	10 mg/ml	+
1 & 5 mg/ml	+ Phenytoin sodium	50 mg/ml	+
5 mg/ml	+ Piperacillin sodium	20 mg/ml	+
1 & 5 mg/ml	+ Piperacillin sodium	200 mg/ml	+
1 & 5 mg/ml	+ Potassium chloride	80 mEq/l	+
5 mg/ml	+ Potassium chloride	2000 mEq/l	+
5 mg/ml	+ Potassium phosphate	0.015 mmol/ml	+
5 mg/ml	+ Procainamide hydrochloride	2 mg/ml	+
5 mg/ml	+ Procainamide hydrochloride	500 mg/ml	+
1 & 5 mg/ml	+ Procainamide hydrochloride	50 mg/ml	+
1 & 5 mg/ml	+ Ranitidine hydrochloride	25 mg/ml	+
5 mg/ml	+ Ranitidine hydrochloride	0.5 & 1 mg/ml	+
1 & 5 mg/ml	+ Rifampicin	6 mg/ml	+
5 mg/ml	+ Sodium bicarbonate	84 mg/ml	+
1 mg/ml	+ Sodium bicarbonate	84 mg/ml	+
5 mg/ml	+ Theophylline	0.8 mg/ml	+
1 & 5 mg/ml	+ Ticarcillin / clavulanic acid	200 mg/ml	+
5 mg/ml	+ Ticarcillin / clavulanic acid	10 mg/ml	+
5 mg/ml	+ Tobramycin sulfate	2.4 & 40 mg/ml	+
5 mg/ml	+ Vancomycin hydrochloride	5 & 50 mg/ml	+

Dobutamine hydrochloride

1 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Dopamine hydrochloride

0.8 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Doxycycline hyclate

1 & 10 mg/ml

Diltiazem hydrochloride

5 mg/ml

Epinephrine hydrochloride

	4 µg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	50 µg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Erythromycin lactobionate

5 & 50 mg/ml

Diltiazem hydrochloride

5 mg/ml

Fluconazole

2 mg/ml

Diltiazem hydrochloride

5 mg/ml

Furosemide

10 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Gentamicin sulfate

2.4 & 40 mg/ml

Diltiazem hydrochloride

5 mg/ml

Heparin sodium

20000 UI/ml	+ Diltiazem hydrochloride	1 mg/ml	+
20000 UI/ml	+ Diltiazem hydrochloride	5 mg/ml	+
80 >> 10000 UI/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Hetastarch

60 mg/ml

Diltiazem hydrochloride

5 mg/ml

Human albumin

	50 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	250 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Hydrocortisone sodium succinate

50 & 125 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
50 & 125 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
1 & 2 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Imipenem - cilastatin sodium

5 mg/ml

Diltiazem hydrochloride

5 mg/ml

Insulin

	0.4 UI/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	100 UI/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Lidocaine hydrochloride

	10 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	4 & 8 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Lorazepam

	2 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
	4 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Methylprednisolone sodium succinate

	2.5 >> 62.5 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
	2.5 >> 62.5 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Metoclopramide hydrochloride

	0.2 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	5 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Metronidazole

5 & 8 mg/ml

Diltiazem hydrochloride

5 mg/ml

Morphine sulfate

	0.4 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	15 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Nafcillin sodium

	10 & 200 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+
	10 & 200 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Nitroglycerin

0.4 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Nitroprusside sodium

0.2 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Oxacillin sodium

	100 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	10 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Penicillin G potassium

	0.1 MUI/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	1 MUI/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Pentamidine isetionate

6 & 30 mg/ml

Diltiazem hydrochloride

5 mg/ml

Pethidine hydrochloride

	10 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	100 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Phenytoin sodium

50 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Piperacillin sodium

	20 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	200 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Potassium chloride

	2000 mEq/l	+ Diltiazem hydrochloride	5 mg/ml	+
	80 mEq/l	+ Diltiazem hydrochloride	1 & 5 mg/ml	+

Potassium phosphate

0.015 mmol/ml

Diltiazem hydrochloride

5 mg/ml

Procainamide hydrochloride

500 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
50 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
2 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Ranitidine hydrochloride

	25 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	0.5 & 1 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Rifampicin

6 mg/ml

Diltiazem hydrochloride

1 & 5 mg/ml

Sodium bicarbonate

	84 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+
	84 mg/ml	+ Diltiazem hydrochloride	1 mg/ml	+

Theophylline

0.8 mg/ml

Diltiazem hydrochloride

5 mg/ml

Ticarcillin / clavulanic acid

	200 mg/ml	+ Diltiazem hydrochloride	1 & 5 mg/ml	+
	10 mg/ml	+ Diltiazem hydrochloride	5 mg/ml	+

Tobramycin sulfate

2.4 & 40 mg/ml

Diltiazem hydrochloride

5 mg/ml

Vancomycin hydrochloride

5 & 50 mg/ml

Diltiazem hydrochloride

5 mg/ml

Mentions Légales