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Antibiotic   Imipenem - cilastatin sodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Andatin Denmark, Norway
Arzomeba Chile, Mexico
Bacqure Ecuador, Morocco, Peru
Cilapem Turkey
Gimipen Colombia
Linataz Colombia
Menepim Venezuela
Perloyem Argentina
Primaxin Canada, Great Britain, Greece, New Zealand, Peru, United States of America
Silanem Turkey
Silpen Chile
Tenacid Italy
Tesilan Colombia
Tienam Brazil, Colombia, Croatia, Denmark, Ecuador, Egypt, Finland, France, Hungary, Iran, Malaysia, Mexico, Morocco, Netherlands, Norway, Poland, Portugal, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates
Zienam Argentina, Austria, Germany, Venezuela
Stability in solutions   injection   Stability in solutions : Imipenem - cilastatin sodium     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 2.5 mg/ml 4°C Protect from light
72 Hour
21
Level of evidence B
Glass Water for Injection 2.5 & 5 mg/ml 25°C Not specified
9 Hour
21
Level of evidence B
Glass Water for Injection 5 mg/ml 4°C Protect from light
48 Hour
21
Level of evidence B
Glass Sodium chloride 0,9% 2.5 mg/ml 4°C Protect from light
72 Hour
21
Level of evidence B
Glass Sodium chloride 0,9% 2.5 & 5 mg/ml 25°C Not specified
9 Hour
21
Level of evidence B
Glass Sodium chloride 0,9% 5 mg/ml 4°C Protect from light
48 Hour
21
Level of evidence B
Glass Glucose 5% 2.5 mg/ml 25°C Not specified
6 Hour
21
Level of evidence B
Glass Glucose 5% 2.5 & 5 mg/ml 4°C Protect from light
24 Hour
21
Level of evidence B
Glass Glucose 5% 5 mg/ml 25°C Not specified
3 Hour
21
Level of evidence B
Glass Ringer’s lactate solution 2.5 mg/ml 25°C Not specified
6 Hour
21
Level of evidence B
Glass Ringer’s lactate solution 2.5 & 5 mg/ml 4°C Protect from light
24 Hour
21
Level of evidence B
Glass Ringer’s lactate solution 5 mg/ml 25°C Not specified
3 Hour
21
Level of evidence B
Glass Glucose 10% 2.5 & 5 mg/ml 25°C Not specified
3 Hour
21
Level of evidence B
Glass Glucose 10% 2.5 & 5 mg/ml 4°C Protect from light
24 Hour
21
Level of evidence B
Polyethylene NaCl 0,9% or Glucose 5% 2,5 mg/ml 22°C Protect from light
24 Hour
1067
Level of evidence C
Polyethylene NaCl 0,9% or Glucose 5% 2,5 mg/ml 4°C Protect from light
24 Hour
1067
Level of evidence C
Ethylene vinyl acetate Sodium chloride 0,9% 2,5 & 5 mg/ml 4°C Protect from light
3 Day
1811
Level of evidence B+
Polyisoprene elastomer Glucose 5% 5 mg/ml 25°C Not specified
24 Hour
604
Manufacturer's stability data
Polyisoprene elastomer Glucose 5% 5 mg/ml 4°C Protect from light
3 Day
604
Manufacturer's stability data
Elastomer (unspecified) Water for Injection 8 mg/ml 25°C Not specified
3 Hour
2042
Level of evidence D
Elastomer (unspecified) Water for Injection 8 mg/ml 37°C Not specified
2 Hour
2042
Level of evidence D
Not specified NaCl 0,9% or Glucose 5% 5 mg/ml 2-8°C Not specified
8 Hour
4298
Level of evidence C
Not specified NaCl 0,9% or Glucose 5% 5 mg/ml 23-27°C Not specified
4 Hour
4298
Level of evidence C
  Mentions Légales