Last update :
18/07/2024
References   References 1721  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=316

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Williams KY, Baker MB.
Title : Compatibility screening of Hextend during simulated Y-site administration with other drugs.
Reference : Int J Pharm Compound ; 5: 69-72. 2001

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAlfentanil hydrochloride Analgesic
Compatible 125 µg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAminophylline Various
Compatible 2.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 4 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAmphotericin B Antifungal
Incompatible 0.6 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 20/10 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAtracurium besylate Curarimimetic
Compatible 0.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAzithromycine Antibiotic
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionAztreonam Antibiotic
Compatible 40 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionBumetanide Diuretic
Compatible 0.04 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionButorphanol tartrate Analgesic
Compatible 0.04 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCefepime dihydrochloride Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCefoperazone sodium Antibiotic
Compatible 40 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCefotaxime sodium Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCefoxitin sodium Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCeftazidime Antibiotic
Compatible 40 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCeftizoxime sodium Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 12 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCisatracurium besylate Curarimimetic
Compatible 0.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionClindamycin phosphate Antibiotic
Compatible 10 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionCo-trimoxazole Antibiotic
Compatible 4/0.8 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDiltiazem hydrochloride Anti-arrhythmic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDolasetron mesylate Antiemetic
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDoxycycline hyclate Antibiotic
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionDroperidol Neuroleptic
Compatible 2.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionEnalaprilate Antihypertensive
Compatible 0.1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionEphedrine hydrochloride Sympathomimetic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 50 µg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionFamotidine Antihistamine (H2)
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionFentanyl citrate Analgesic
Compatible 12.5 µg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionFurosemide Diuretic
Compatible 3 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionGranisetron hydrochloride Antiemetic
Compatible 0.05 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionHaloperidol lactate Neuroleptic
Compatible 0.2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionHetastarch Various
Compatible 60 mg/ml + injectionAlfentanil hydrochloride 125 µg/ml + specific solvent
Compatible 60 mg/ml + injectionAmikacin sulfate 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAminophylline 2.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAmiodarone hydrochloride 4 mg/ml + specific solvent
Incompatible 60 mg/ml + injectionAmphotericin B 0.6 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAmpicillin sodium 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAmpicillin sodium - sulbactam sodium 20/10 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAtracurium besylate 0.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAzithromycine 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionAztreonam 40 mg/ml + specific solvent
Compatible 60 mg/ml + injectionBumetanide 0.04 mg/ml + specific solvent
Compatible 60 mg/ml + injectionButorphanol tartrate 0.04 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCalcium gluconate 40 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCefazolin sodium 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCefepime dihydrochloride 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCefoperazone sodium 40 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCefotaxime sodium 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCefoxitin sodium 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCeftazidime 40 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCeftizoxime sodium 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCeftriaxone disodium 20 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCefuroxime sodium 30 mg/ml + specific solvent
Compatible 60 mg/ml + injectionChlorpromazine hydrochloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCimetidine hydrochloride 12 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCisatracurium besylate 0.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionClindamycin phosphate 10 mg/ml + specific solvent
Compatible 60 mg/ml + injectionCo-trimoxazole 4/0.8 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + specific solvent
Incompatible 60 mg/ml + injectionDiazepam 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDigoxin 250 µg/ml + specific solvent
Compatible 60 mg/ml + injectionDiltiazem hydrochloride 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDolasetron mesylate 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDoxycycline hyclate 1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionDroperidol 2.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionEnalaprilate 0.1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionEphedrine hydrochloride 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionEpinephrine hydrochloride 50 µg/ml + specific solvent
Compatible 60 mg/ml + injectionErythromycin lactobionate 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + specific solvent
Compatible 60 mg/ml + injectionFamotidine 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionFentanyl citrate 12.5 µg/ml + specific solvent
Compatible 60 mg/ml + injectionFluconazole 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionFurosemide 3 mg/ml + specific solvent
Compatible 60 mg/ml + injectionGentamicin sulfate 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionGranisetron hydrochloride 0.05 mg/ml + specific solvent
Compatible 60 mg/ml + injectionHaloperidol lactate 0.2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionHeparin sodium 100 UI/ml + specific solvent
Compatible 60 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionHydroxyzine dihydrochloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionIsoprenaline hydrochloride 0.02 mg/ml + specific solvent
Compatible 60 mg/ml + injectionKetorolac tromethamine 15 mg/ml + specific solvent
Compatible 60 mg/ml + injectionLabetalol hydrochloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionLevofloxacine 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionLidocaine hydrochloride 8 mg/ml + specific solvent
Compatible 60 mg/ml + injectionLorazepam 0.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMagnesium sulfate 100 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMannitol 150 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMetronidazole 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMilrinone lactate 0.2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMivacurium 0.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionMorphine sulfate 1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionNalbuphine hydrochloride 10 mg/ml + specific solvent
Compatible 60 mg/ml + injectionNitroglycerin 0.4 mg/ml + specific solvent
Compatible 60 mg/ml + injectionNitroprusside sodium 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionNorepinephrine bitartrate 0.12 mg/ml + specific solvent
Compatible 60 mg/ml + injectionOfloxacin 4 mg/ml + specific solvent
Compatible 60 mg/ml + injectionOndansetron hydrochloride 1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPancuronium bromide 0.1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPethidine hydrochloride 4 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPhenylephrine hydrochloride 1 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPiperacillin sodium 40 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPiperacillin sodium / tazobactam 40/5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPotassium chloride 100 mEq/l + specific solvent
Compatible 60 mg/ml + injectionProcainamide hydrochloride 10 mg/ml + specific solvent
Compatible 60 mg/ml + injectionProchlorperazine edysilate 0.5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionPromethazine hydrochloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionRanitidine hydrochloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionRocuronium bromide 1 mg/ml + specific solvent
Incompatible 60 mg/ml + injectionSodium bicarbonate 84 mg/ml + specific solvent
Compatible 60 mg/ml + injectionSufentanil citrate 0.0125 mg/ml + specific solvent
Compatible 60 mg/ml + injectionSuxamethonium chloride 2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionTheophylline 4 mg/ml + specific solvent
Compatible 60 mg/ml + injectionThiopental sodium 25 mg/ml + specific solvent
Compatible 60 mg/ml + injectionTicarcillin / clavulanic acid 31 mg/ml + specific solvent
Compatible 60 mg/ml + injectionTobramycin sulfate 5 mg/ml + specific solvent
Compatible 60 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + specific solvent
Compatible 60 mg/ml + injectionVecuronium bromide 0.2 mg/ml + specific solvent
Compatible 60 mg/ml + injectionVerapamil hydrochloride 1.25 mg/ml + specific solvent
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionHydroxyzine dihydrochloride Anxiolytic
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0.02 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionKetorolac tromethamine Anti-inflammatory
Compatible 15 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionLabetalol hydrochloride Beta-blocker
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionLevofloxacine Antibiotic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionLidocaine hydrochloride Local anesthetic
Compatible 8 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionLorazepam Anxiolytic
Compatible 0.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMannitol Various
Compatible 150 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMilrinone lactate Cardiotonic
Compatible 0.2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMivacurium Curarimimetic
Compatible 0.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionNalbuphine hydrochloride Antidote
Compatible 10 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionNitroprusside sodium Vasodilator
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.12 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionOfloxacin Antibiotic
Compatible 4 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionOndansetron hydrochloride Antiemetic
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPancuronium bromide Curarimimetic
Compatible 0.1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPethidine hydrochloride Analgesic
Compatible 4 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPhenylephrine hydrochloride Sympathomimetic
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPiperacillin sodium Antibiotic
Compatible 40 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 40/5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPotassium chloride Electrolyte
Compatible 100 mEq/l + injectionHetastarch 60 mg/ml + specific solvent
injectionProcainamide hydrochloride Anti-arrhythmic
Compatible 10 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionProchlorperazine edysilate Neuroleptic
Compatible 0.5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionRocuronium bromide Curarimimetic
Compatible 1 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionSufentanil citrate Analgesic
Compatible 0.0125 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionSuxamethonium chloride Curarimimetic
Compatible 2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionTheophylline Various
Compatible 4 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionThiopental sodium General anesthetic
Compatible 25 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionTicarcillin / clavulanic acid Antibiotic
Compatible 31 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionVecuronium bromide Curarimimetic
Compatible 0.2 mg/ml + injectionHetastarch 60 mg/ml + specific solvent
injectionVerapamil hydrochloride Anti-arrhythmic
Compatible 1.25 mg/ml + injectionHetastarch 60 mg/ml + specific solvent

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