Last update :
19/11/2024
References   References 2006  
Type : Journal
Web link : http://archive.hospital-pharmacy.com/doi/ref/10.1310/hpj5007-609

Research teams : San Francisco - Theravance Biopharma
Authors : Gu Z, Wong A, Raquinio E, Nguyen A.
Title : Stability of Reconstituted Telavancin Drug Product in Frozen Intravenous Bags.
Reference : Hosp Pharm ; 50, 7: 609-614. 2015

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products identified and quantified

List of drugs
injectionTelavancin hydrochloride Antibiotic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0.6 mg/ml -20°C Protect from light
32 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 8 mg/ml -20°C Protect from light
32 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 0.6 mg/ml -20°C Protect from light
32 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 8 mg/ml -20°C Protect from light
32 Day

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