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Anticancer drug   Etoposide phosphate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Etopofos Argentina, Austria, Denmark, Finland, Norway, Sweden
Etopophos Belgium, Bulgaria, France, Germany, Great Britain, Israel, Luxembourg, Netherlands, New Zealand, Poland, Republic of South Africa, Switzerland, United States of America
Nexvep Brazil
Toposar United States of America
Stability in solutions   injection   Stability in solutions : Etoposide phosphate     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 10 & 20 mg/ml 2-8°C Protect from light
7 Day
3655
Manufacturer's stability data
Glass Water for Injection 10 & 20 mg/ml 25°C Light
96 Hour
3655
Manufacturer's stability data
Glass Water for Injection 10 & 20 mg/ml 37°C Light
48 Hour
3655
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% > 0,1 mg/ml 2-8°C Protect from light
7 Day
3655
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% > 0,1 mg/ml 25°C Light
96 Hour
3655
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% > 0,1 mg/ml 37°C Light
48 Hour
3655
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% 10 & 20 mg/ml 2-8°C Protect from light
7 Day
3655
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% 10 & 20 mg/ml 25°C Light
96 Hour
3655
Manufacturer's stability data
Glass NaCl 0,9% or Glucose 5% 10 & 20 mg/ml 37°C Light
48 Hour
3655
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% > 0,1 mg/ml 2-8°C Protect from light
7 Day
3655
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% > 0,1 mg/ml 25°C Light
96 Hour
3655
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% > 0,1 mg/ml 37°C Light
48 Hour
3655
Manufacturer's stability data
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 23°C Not specified
31 Day
1411
Level of evidence B+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 32°C Not specified
7 Day
1411
Level of evidence B+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,1 & 10 mg/ml 4°C Protect from light
31 Day
1411
Level of evidence B+
Polyolefine NaCl 0,9% or Glucose 5% > 0,1 mg/ml 2-8°C Protect from light
7 Day
3655
Manufacturer's stability data
Polyolefine NaCl 0,9% or Glucose 5% > 0,1 mg/ml 25°C Light
96 Hour
3655
Manufacturer's stability data
Polyolefine NaCl 0,9% or Glucose 5% > 0,1 mg/ml 37°C Light
48 Hour
3655
Manufacturer's stability data
Polypropylen Syringe Water for injection + antibacterial 10 & 20 mg/ml 23°C Not specified
31 Day
1411
Level of evidence B+
Polypropylen Syringe Water for injection + antibacterial 10 & 20 mg/ml 32°C Not specified
7 Day
1411
Level of evidence B+
Polypropylen Syringe Water for injection + antibacterial 10 & 20 mg/ml 4°C Protect from light
31 Day
1411
Level of evidence B+
  Mentions Légales