Last update :
18/07/2024
References   References 3767  
Type : Journal
Web link : http://www.pharmactuel.com/index.php/pharmactuel/issue/view/101

Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Legris M.E, Lavoie A, Forrest J.M, Hildgen P.
Title : Compatibilité par évaluation visuelle du thiopental injectable lors de son administration en Y avec des médicaments usuels.
Reference : Pharmactuel ; 47, 3 : 167-172. 2014

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionAmikacin sulfate Antibiotic
Incompatible 250 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionAmiodarone hydrochloride Anti-arrhythmic
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionAmphotericin B Antifungal
Incompatible + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionAmpicillin sodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionAzithromycine Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCalcium chloride Electrolyte
Incompatible 78 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCalcium gluconate Electrolyte
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCaspofungin acetate Antifungal
Incompatible + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCefazolin sodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCefotaxime sodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCefoxitin sodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCeftazidime Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCeftriaxone disodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCefuroxime sodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionChlorpromazine hydrochloride Anxiolytic
Incompatible 25 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCiclosporin Immunosuppressant
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCiprofloxacin lactate Antibiotic
Incompatible 2 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionClindamycin phosphate Antibiotic
Incompatible 150 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCloxacillin sodium Antibiotic
Incompatible 100 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionCo-trimoxazole Antibiotic
Compatible 16/80 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 4 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionDimenhydrinate Antihistamine (H1)
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionDobutamine hydrochloride Cardiotonic
Incompatible 12.5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionDopamine hydrochloride Cardiotonic
Incompatible 40 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionErythromycin lactobionate Antibiotic
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionFentanyl citrate Analgesic
Incompatible 50 µg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionFluconazole Antifungal
Incompatible 2 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionGentamicin sulfate Antibiotic
Incompatible 40 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Incompatible 1000 UI/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 125 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionHydromorphone hydrochloride Analgesic
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionInsulin Glucose-lowering
Compatible + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionLorazepam Anxiolytic
Compatible 4 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionMagnesium sulfate Electrolyte
Incompatible 500 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionMeropenem Antibiotic
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionMetoclopramide hydrochloride Antiemetic
Incompatible 5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionMetronidazole Antiparasitic
Incompatible 5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionMidazolam hydrochloride Anxiolytic
Incompatible 5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionMilrinone lactate Cardiotonic
Incompatible 1 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionNitroprusside sodium Vasodilator
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionNorepinephrine bitartrate Sympathomimetic
Incompatible 1 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionOctreotide acetate Various
Incompatible 0.5 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionOxytocin Various
Incompatible 10 UI/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPancuronium bromide Curarimimetic
Incompatible 2 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPantoprazole sodium Proton pump inhibitor
Incompatible 4 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPiperacillin sodium Antibiotic
Incompatible 200 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 200 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPotassium chloride Electrolyte
Incompatible + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPotassium phosphate Electrolyte
Incompatible 3 mmol/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionPromethazine hydrochloride Antihistamine (H1)
Incompatible 25 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionRanitidine hydrochloride Antihistamine (H2)
Incompatible 25 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionRocuronium bromide Curarimimetic
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionSalbutamol sulfate Beta-stimulant
Incompatible 1 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionThiopental sodium General anesthetic
Incompatible 25 mg/ml + injectionAciclovir sodium 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionAmikacin sulfate 250 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionAmiodarone hydrochloride 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionAmphotericin B + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionAmpicillin sodium 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionAzithromycine 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCalcium chloride 78 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCalcium gluconate 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCaspofungin acetate + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCefazolin sodium 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCefotaxime sodium 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCefoxitin sodium 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCeftazidime 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCeftriaxone disodium 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCefuroxime sodium 100 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionChlorpromazine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCiclosporin 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionClindamycin phosphate 150 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionCloxacillin sodium 100 mg/ml + Sodium chloride 0,9%
Compatible 25 mg/ml + injectionCo-trimoxazole 16/80 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionDexamethasone sodium phosphate 4 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionDiazepam 5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionDimenhydrinate 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionDiphenhydramine hydrochloride 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionDobutamine hydrochloride 12.5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionDopamine hydrochloride 40 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionErythromycin lactobionate 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionFentanyl citrate 50 µg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionGentamicin sulfate 40 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionHeparin sodium 1000 UI/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionHydrocortisone sodium succinate 125 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionHydromorphone hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 25 mg/ml + injectionInsulin + Sodium chloride 0,9%
Compatible 25 mg/ml + injectionLorazepam 4 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionMagnesium sulfate 500 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionMeropenem 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionMetronidazole 5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionMilrinone lactate 1 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionNitroglycerin 5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionNitroprusside sodium 10 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionNorepinephrine bitartrate 1 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionOctreotide acetate 0.5 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionOxytocin 10 UI/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPancuronium bromide 2 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPantoprazole sodium 4 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPhenytoin sodium 50 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPiperacillin sodium 200 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPiperacillin sodium / tazobactam 200 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPotassium chloride + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPotassium phosphate 3 mmol/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionPromethazine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionRanitidine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionRocuronium bromide 10 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionSalbutamol sulfate 1 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionTicarcillin / clavulanic acid 200 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionTobramycin sulfate 40 mg/ml + Sodium chloride 0,9%
Incompatible 25 mg/ml + injectionVancomycin hydrochloride 50 mg/ml + Sodium chloride 0,9%
injectionTicarcillin / clavulanic acid Antibiotic
Incompatible 200 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionTobramycin sulfate Antibiotic
Incompatible 40 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%
injectionVancomycin hydrochloride Antibiotic
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Sodium chloride 0,9%

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