Last update :
19/11/2024
Antidote   N-acetylcysteine  
injection
aerosol Eye-drops Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acetadote New Zealand, United States of America
Acetylcystein Canada, Denmark
Acetylcysteine Great Britain, Iran
Cilol India
DBL acetylcysteine Malaysia, New Zealand
Fluimucil Colombia, Ecuador, France, Germany, Hungary, Netherlands, Poland, Portugal, Switzerland
Hidonac France, Italy, Malaysia, Romania, Spain
Mucare India
Mucofrin Italy
Mucomelt India
Mucomix India
Mucosys India
Nacel India
Parvolex Canada, Great Britain, Greece
Compatibility   injection   Compatibility : N-acetylcysteine              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Aciclovir sodium 50 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Amikacin sulfate 250 mg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Aminophylline 50 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Amiodarone hydrochloride 50 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Amphotericin B
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Ampicillin sodium
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Atropine sulfate 0.4 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Azithromycine 500 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Bretylium tosilate 50 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection N-acetylcysteine 200 mg/ml
injection Caffeine 10 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Calcium chloride 78 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Calcium gluconate 100 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Caspofungin acetate
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Cefazolin sodium
None 3766
Chemical instability Incompatible
injection N-acetylcysteine 100 mg/ml
injection Cefepime dihydrochloride 125 mg/ml
Water for Injection 2141
Compatible
injection N-acetylcysteine 200 mg/ml
injection Cefotaxime sodium
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Cefoxitin sodium
None 3766
Chemical instability Incompatible
injection N-acetylcysteine 100 mg/ml
injection Ceftazidime 125 mg/ml
Water for Injection 2141
Chemical instability Incompatible
injection N-acetylcysteine 100 mg/ml
injection Ceftazidime 83.3 mg/ml
1759
Compatible
injection N-acetylcysteine 200 mg/ml
injection Ceftazidime
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Ceftriaxone disodium
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Cefuroxime sodium
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Chlorpromazine hydrochloride 25 mg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Ciclosporin 50 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Ciprofloxacin lactate 2 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Clindamycin phosphate 150 mg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Cloxacillin sodium
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection N-acetylcysteine 200 mg/ml
injection Co-trimoxazole 16/80 mg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Dexamethasone sodium phosphate 4 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Dexmedetomidine 100 µg/ml
4389
Compatible
injection N-acetylcysteine 200 mg/ml
injection Diazepam 5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Digoxin 50 µg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Diphenhydramine hydrochloride 50 mg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Dobutamine hydrochloride 12.5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Dopamine hydrochloride 3.2 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Droperidol 2.5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Enalaprilate 1.25 mg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Epinephrine hydrochloride 1000 µg/ml
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Erythromycin lactobionate
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Fentanyl citrate 50 µg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Fluconazole 2 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Furosemide 10 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Gentamicin sulfate 40 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Heparin sodium 1000 UI/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Hydralazine hydrochloride
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Hydrocortisone sodium succinate
None 3766
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Insulin 100 UI/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Labetalol hydrochloride 5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Lidocaine hydrochloride 1 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Mannitol 250 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Unspecified incompatibility Incompatible
injection N-acetylcysteine 200 mg/ml
injection Metronidazole 5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
injection N-acetylcysteine 200 mg/ml
injection Potassium chloride 200 mEq/l
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Propranolol hydrochloride 1 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Ranitidine hydrochloride 25 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
Ringer’s lactate solution 4603
Compatible
injection N-acetylcysteine 200 mg/ml
injection Midazolam hydrochloride 5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Milrinone lactate 1 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Nitroglycerin 5 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Norepinephrine bitartrate 1 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Piperacillin sodium
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Piperacillin sodium / tazobactam
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Rocuronium bromide 10 mg/ml
None 3766
Compatible
injection N-acetylcysteine 200 mg/ml
injection Sodium bicarbonate 84 mg/ml
None 3766
Compatible
injection N-acetylcysteine 100 mg/ml
injection Sugammadex 100 mg/ml
None 3372
Compatible
injection N-acetylcysteine 100 mg/ml
injection Temocilline 83.33 mg/ml
Water for Injection 2231
Compatible
injection N-acetylcysteine 200 mg/ml
injection Ticarcillin / clavulanic acid 31 mg/ml
None 3766
Compatible
injection N-acetylcysteine 100 mg/ml
injection Vancomycin hydrochloride 10 mg/ml
Glucose 5% 3385
Compatible
injection N-acetylcysteine 200 mg/ml
injection Verapamil hydrochloride 2.5 mg/ml
None 3766

  Mentions Légales