Last update :
27/01/2022
References   References 4639  
Type : Journal

Research teams : Montreal - Faculté de pharmacie, Université de Montréal
Authors : Friciu M, Monfort A, Dubé P-A, Leclair G.
Title : Stability of N-Acetylcysteine 60 mg/mL in Extemporaneously Compounded Injectable Solutions.
Reference : Can J Hosp Pharm 2021;74(4):344-9 2021

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values

List of drugs
InjectionN-acetylcysteine Antidote
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 60 mg/ml 23-27°C Light
72 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 60 mg/ml 23-27°C Light
72 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,45% 60 mg/ml 23-27°C Light
72 Hour

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