Last update :
13/11/2024
Analgesic   Remifentanil hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Fenburol Chile, Republic of South Africa
Proximicil Mexico
Redormin Argentina
Remicit Argentina
Remifas Ecuador
Remifentanil Belgium, Canada, Germany, Iceland, New Zealand, Norway, Romania
Remifentanilo Argentina, Portugal, Spain
Remiflo Argentina
Remimed Germany
Restinil Argentina, Ecuador
Sagal Argentina
Ultiva Australia, Austria, Belgium, Chile, Colombia, Denmark, Ecuador, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Iran, Ireland, Italy, Luxembourg, Malaysia, Netherlands, New Zealand, Norway, Peru, Poland, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United States of America, Venezuela
Compatibility   injection   Compatibility : Remifentanil hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Aciclovir sodium 7 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Alfentanil hydrochloride 125 µg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Amikacin sulfate 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Aminophylline 2.5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 µg/ml
injection Amphotericin B 0.6 mg/ml
Glucose 5% 59
Immediate precipitation Incompatible
injection Remifentanil hydrochloride 250 µg/ml
injection Amphotericin B 0.6 mg/ml
Glucose 5% 59
Immediate precipitation Incompatible
injection Remifentanil hydrochloride 500 µg/ml
injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ampicillin sodium 20 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ampicillin sodium - sulbactam sodium 20/10 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Aztreonam 40 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Bretylium tosilate 4 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Bumetanide 0.04 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Buprenorphine hydrochloride 0.04 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Butorphanol tartrate 0.04 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Calcium gluconate 40 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Cefazolin sodium 20 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 200 µg/ml
injection Cefepime dihydrochloride 125 mg/ml
Water for Injection 2141
Immediate turbidity Incompatible
injection Remifentanil hydrochloride 250 µg/ml
injection Cefoperazone sodium 40 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 µg/ml
injection Cefoperazone sodium 40 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Cefotaxime sodium 20 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Cefoxitin sodium 20 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 250 µg/ml
injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Compatible
injection Remifentanil hydrochloride 250 µg/ml
injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ceftazidime 40 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 200 µg/ml
injection Ceftazidime 125 mg/ml
Water for Injection 2141
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ceftizoxime sodium 20 mg/ml
Sodium chloride 0,9% 59
Immediate precipitation Incompatible
injection Remifentanil hydrochloride 250 µg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
injection Remifentanil hydrochloride 250 µg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Unspecified incompatibility Incompatible
injection Remifentanil hydrochloride
injection Ceftobiprole medocaril sodium
4650
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ceftriaxone disodium 20 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Cefuroxime sodium 30 mg/ml
Sodium chloride 0,9% 59
Immediate turbidity Incompatible
injection Remifentanil hydrochloride 25 µg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 250 µg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Cimetidine hydrochloride 12 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ciprofloxacin lactate 1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Cisatracurium besylate 2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Cisatracurium besylate 5 mg/ml
Sodium chloride 0,9% 3823
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Clindamycin phosphate 10 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Co-trimoxazole 0.8/4 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 250 µg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Immediate precipitation Incompatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Diazepam 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Diazepam 0.25 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Digoxin 250 µg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Diphenhydramine hydrochloride 2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Dobutamine hydrochloride 4 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Dopamine hydrochloride 3.2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Doxycycline hyclate 1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Droperidol 2.5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Enalaprilate 0.1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Epinephrine hydrochloride 50 µg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Esmolol hydrochloride 10 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Famotidine 2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 200 µg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Fentanyl citrate 12.5 µg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 59
Precipitation after 15 minutes Incompatible
injection Remifentanil hydrochloride 120 µg/ml
injection Furosemide 1 mg/ml
Glucose 5% 3294
Immediate precipitation Incompatible
injection Remifentanil hydrochloride 120 µg/ml
injection Furosemide 1 mg/ml
Glucose 5% 3176
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Furosemide 3 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ganciclovir sodium 20 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Gentamicin sulfate 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Haloperidol lactate 0.2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Haloperidol lactate 0.5 mg/ml
Sodium chloride 0,9% 3823
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Heparin sodium 416.7 UI/ml
Glucose 5% 3294
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Heparin sodium 100 UI/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Heparin sodium 500 UI/ml
Sodium chloride 0,9% 3823
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Heparin sodium 416.7 UI/ml
Glucose 5% 3176
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Hydroxyzine dihydrochloride 2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Imipenem - cilastatin sodium 10 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Insulin 1 UI/ml
Glucose 5% 3176
Immediate turbidity Incompatible
injection Remifentanil hydrochloride 100 µg/ml
injection Insulin 1 UI/ml
Sodium chloride 0,9% 4698
Compatible
injection Remifentanil hydrochloride 500 µg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Mannitol 150 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Midazolam hydrochloride 2.1 mg/ml
Sodium chloride 0,9% 3823
Unspecified incompatibility Incompatible
injection Remifentanil hydrochloride
NaHCO3 4501
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Isoprenaline hydrochloride 0.02 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ketorolac tromethamine 15 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Lidocaine hydrochloride 8 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Lorazepam 0.5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Magnesium sulfate 8 mg/ml
Glucose 5% 3176
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Magnesium sulfate 100 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Metoclopramide hydrochloride 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Metronidazole 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 20 µg/ml
injection Midazolam hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 3294
Unspecified incompatibility Incompatible
injection Remifentanil hydrochloride
Ringer’s lactate solution 3519
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 3176
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Midazolam hydrochloride 1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Minocycline hydrochloride 0.2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Morphine sulfate 1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Nalbuphine hydrochloride 10 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Netilmicin sulfate 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Nitroglycerin 0.4 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Norepinephrine bitartrate 0.12 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ofloxacin 4 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 59
Immediate precipitation Incompatible
injection Remifentanil hydrochloride 1000 µg/ml
injection Oxytocin 10 UI/ml
4389
Compatible
injection Remifentanil hydrochloride 20 µg/ml
injection Pantoprazole sodium 0.32 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Remifentanil hydrochloride 1000 µg/ml
injection Paracetamol 10 mg/ml
4742
Unspecified incompatibility Incompatible
injection Remifentanil hydrochloride
injection Parecoxib sodium
3504
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Pethidine hydrochloride 4 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Phenylephrine hydrochloride 1 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Piperacillin sodium 40 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Potassium chloride 1000 mEq/l
Glucose 5% 3176
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Potassium chloride 100 mEq/l
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride
injection Potassium phosphate
3781
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Potassium phosphate 1 mmol/ml
Glucose 5% 3176
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Potassium phosphate 1 mmol/ml
Glucose 5% 3294
Immediate instability of the emulsion Incompatible
injection Remifentanil hydrochloride 25 >> 47.6 µg/ml
injection Propofol 0.47 >> 18 mg/ml
None 4331
Compatible
injection Remifentanil hydrochloride 2.38 µg/ml
injection Propofol 9.52 & 19.05 mg/ml
None 4331
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Propofol 20 mg/ml
Glucose 5% 3176
Unspecified incompatibility Incompatible
injection Remifentanil hydrochloride
injection Propofol
3519
Compatible
injection Remifentanil hydrochloride 120 µg/ml
injection Propofol 20 mg/ml
Glucose 5% 3294
Subvisual incompatibility Incompatible
injection Remifentanil hydrochloride 4.5 >> 45.5 µg/ml
injection Propofol 1.8 >> 18.2 mg/ml
None 4011
Immediate instability of the emulsion Incompatible
injection Remifentanil hydrochloride 50 et 100 µg/ml
injection Propofol 10 et 20 mg/ml
None 2325
Unspecified incompatibility Incompatible
injection Remifentanil hydrochloride 10 >> 50 µg/ml
injection Propofol 9.5 mg/ml
NaHCO3 4501
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Remimazolam 5 mg/ml
Sodium chloride 0,9% 4723
Compatible
injection Remifentanil hydrochloride 100 µg/ml
injection Rocuronium bromide 10 mg/ml
Sodium chloride 0,9% 3823
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Sufentanil citrate 0.0125 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 5000 µg/ml
injection Sugammadex 100 mg/ml
None 3372
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Theophylline 3.2 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Thiopental sodium 50 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Ticarcillin / clavulanic acid 31 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Tobramycin sulfate 5 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Vancomycin hydrochloride 10 mg/ml
Sodium chloride 0,9% 59
Compatible
injection Remifentanil hydrochloride 25 & 250 µg/ml
injection Zidovudine 4 mg/ml
Sodium chloride 0,9% 59

  Mentions Légales