Last update :
19/11/2024
Vasodilator   Nitroprusside sodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Nipride Canada, Netherlands
Nipruss Egypt, Germany
Nitropress Iran, New Zealand, United States of America
Nitroprussiate FID France
Compatibility   injection   Compatibility : Nitroprusside sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Nitroprusside sodium 0,4 mg/ml
injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Argatroban 1 mg/ml
Glucose 5% 1963
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Atracurium besylate 0.5 mg/ml
Glucose 5% 402
Compatible
injection Nitroprusside sodium 2 mg/ml
injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
injection Nitroprusside sodium 25 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
injection Nitroprusside sodium 0.5 mg/ml
injection Cimetidine hydrochloride 3 mg/ml
Glucose 5% 1201
Compatible
injection Nitroprusside sodium 2 mg/ml
injection Cisatracurium besylate 0.1 mg/ml
Glucose 5% 299
Immediate precipitation Incompatible
injection Nitroprusside sodium 2 mg/ml
injection Cisatracurium besylate 2 & 5 mg/ml
Glucose 5% 299
Compatible
injection Nitroprusside sodium 25 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Nitroprusside sodium 2 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Compatible
injection Nitroprusside sodium 1,2 mg/ml
injection Dobutamine hydrochloride 5 mg/ml
Glucose 5% 3177
Compatible
injection Nitroprusside sodium 1.2 mg/ml
injection Dobutamine hydrochloride 5 mg/ml
Glucose 5% 2879
Compatible
injection Nitroprusside sodium 1.2 mg/ml
injection Dopamine hydrochloride 5 mg/ml
Glucose 5% 3381
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Compatible
injection Nitroprusside sodium 0,91 mg/ml
injection Enalaprilate 0,011 mg/ml
Glucose 5% 963
Compatible
injection Nitroprusside sodium 0,2 mg/ml
injection Esmolol hydrochloride 10 mg/ml
Glucose 5% 363
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Famotidine 0.2 mg/ml
Glucose 5% 398
Compatible
injection Nitroprusside sodium 2 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Fosfomycin 30 mg/ml
Glucose 5% 4055
Immediate precipitation Incompatible
injection Nitroprusside sodium 0.2 mg/ml
injection Haloperidol lactate 5 mg/ml
Glucose 5% 403
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Heparin sodium 100 UI/ml
Glucose 5% 295
Compatible
injection Nitroprusside sodium 25 mg/ml
Ringer’s lactate solution 4603
Compatible
injection Nitroprusside sodium 0.4 mg/ml
Parenteral nutrition (with lipids) 1415
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Heparin sodium 50 UI/ml
None 317
Compatible
injection Nitroprusside sodium 0.4 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Haloperidol lactate 0.5 mg/ml
Glucose 5% 403
Compatible
injection Nitroprusside sodium 2 mg/ml
injection Hetastarch 60 mg/ml
specific solvent 1721
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Indomethacin sodium trihydrate 1 mg/ml
Sodium chloride 0,9% 467
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Insulin 1 UI/ml
Glucose 5% 295
Compatible
injection Nitroprusside sodium 1,25 mg/ml
injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Labetalol hydrochloride 5 mg/ml
Glucose 5% 295
Immediate precipitation Incompatible
injection Nitroprusside sodium 10 mg/ml
injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
injection Nitroprusside sodium 25 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Metoprolol tartrate 1 mg/ml
Glucose 5% 2346
Compatible
injection Nitroprusside sodium 2 mg/ml
injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 295
Compatible
injection Nitroprusside sodium 0,2 mg/ml
injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 176
Compatible
injection Nitroprusside sodium 1.6 mg/ml
injection Milrinone lactate 0.8 mg/ml
Glucose 5% 813
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 295
Compatible
injection Nitroprusside sodium 10 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Nicardipine hydrochloride 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate turbidity Incompatible
injection Nitroprusside sodium 0.4 mg/ml
injection Oritavancin 0.8 >>2 mg/ml
Glucose 5% 3152
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Pancuronium bromide 0.05 mg/ml
Glucose 5% 402
Precipitation after 15 minutes Incompatible
injection Nitroprusside sodium
injection Pantoprazole sodium
2090
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
injection Nitroprusside sodium 0.4 mg/ml
injection Propofol 10 mg/ml
None 300
Compatible
injection Nitroprusside sodium 0.05 & 0.4 mg/ml
injection Ranitidine hydrochloride 0.05 & 2 mg/ml
NaCl 0,9% or Glucose 5% 214
Compatible
injection Nitroprusside sodium 10 mg/ml
injection Salbutamol sulfate 1 mg/ml
None 3216
Color change after 24 hours Incompatible
injection Nitroprusside sodium 1.2 mg/ml
injection Sodium thiosulfate 10 mg/ml
Glucose 5% 3381
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Sodium thiosulfate 2 mg/ml
NaCl 0,9% or Glucose 5% 4020
Compatible
injection Nitroprusside sodium 12 mg/ml
injection Sugammadex 100 mg/ml
None 3372
Compatible
injection Nitroprusside sodium 0,004 mg/ml
injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Theophylline 4 mg/ml
None 317
Immediate precipitation Incompatible
injection Nitroprusside sodium 10 mg/ml
injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
injection Nitroprusside sodium 0.2 mg/ml
injection Vecuronium bromide 0.1 mg/ml
Glucose 5% 402
Compatible
injection Nitroprusside sodium 0.1 mg/ml
injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057

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