Last update :
19/11/2024
References   References 4650  
Type : Manufacturer

Research teams :
Authors :
Title : Ceftobiprole (Zevtera 500 mg powder for concentrate for solution for infusion.) Summary of Product Characteristics, Advanz Pharma updated 4 aug 2021.
Reference : Advanz Pharma 2021

Level of Evidence : 
Manufacturer's stability data
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAciclovir sodium Antiviral
Incompatible + injectionCeftobiprole medocaril sodium
injectionAmikacin sulfate Antibiotic
Incompatible + injectionCeftobiprole medocaril sodium
injectionAmiodarone hydrochloride Anti-arrhythmic
Incompatible + injectionCeftobiprole medocaril sodium
injectionAmphotericin B Antifungal
Incompatible + injectionCeftobiprole medocaril sodium
injectionCalcium gluconate Electrolyte
Incompatible + injectionCeftobiprole medocaril sodium
injectionCaspofungin acetate Antifungal
Incompatible + injectionCeftobiprole medocaril sodium
injectionCeftobiprole medocaril sodium Antibiotic
Factors which affect stability Storage Light Induces Degradation
Stability in solutions Glass Water for Injection 50 mg/ml 2-8°C Not specified
24 Hour
Stability in solutions Glass Water for Injection 50 mg/ml 25°C Not specified
1 Hour
Stability in solutions Glass Sodium chloride 0,9% 2,67 mg/ml 2-8°C Protect from light
4 Day
Stability in solutions Glass Sodium chloride 0,9% 2,67 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Glass Sodium chloride 0,9% 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Glass Glucose 5% 2,67 mg/ml 2-8°C Protect from light
4 Day
Stability in solutions Glass Glucose 5% 2,67 mg/ml 25°C Protect from light
12 Hour
Stability in solutions Glass Glucose 5% 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Glass Glucose 5% 50 mg/ml 2-8°C Not specified
24 Hour
Stability in solutions Glass Glucose 5% 50 mg/ml 25°C Not specified
1 Hour
Stability in solutions Glass Ringer’s lactate solution 2,67 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Glass Ringer’s lactate solution 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 2,67 mg/ml 2-8°C Protect from light
4 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 2,67 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 2,67 mg/ml 2-8°C Protect from light
4 Day
Stability in solutions Polyvinyl chloride Glucose 5% 2,67 mg/ml 25°C Protect from light
12 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Polyvinyl chloride Ringer’s lactate solution 2,67 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyvinyl chloride Ringer’s lactate solution 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 2,67 mg/ml 2-8°C Protect from light
4 Day
Stability in solutions Polyethylene Sodium chloride 0,9% 2,67 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyethylene Sodium chloride 0,9% 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Polyethylene Glucose 5% 2,67 mg/ml 2-8°C Protect from light
4 Day
Stability in solutions Polyethylene Glucose 5% 2,67 mg/ml 25°C Protect from light
12 Hour
Stability in solutions Polyethylene Glucose 5% 2,67 mg/ml 25°C Light
8 Hour
Stability in solutions Polyethylene Ringer’s lactate solution 2,67 mg/ml 25°C Protect from light
24 Hour
Stability in solutions Polyethylene Ringer’s lactate solution 2,67 mg/ml 25°C Light
8 Hour
Incompatible + injectionAciclovir sodium
Incompatible + injectionAmikacin sulfate
Incompatible + injectionAmiodarone hydrochloride
Incompatible + injectionAmphotericin B
Incompatible + injectionCalcium gluconate
Incompatible + injectionCaspofungin acetate
Incompatible + injectionCiprofloxacin lactate
Incompatible + injectionCisatracurium besylate
Incompatible + injectionDiazepam
Incompatible + injectionDiltiazem hydrochloride
Incompatible + injectionDiphenhydramine hydrochloride
Incompatible + injectionDobutamine hydrochloride
Incompatible + injectionDopamine hydrochloride
Incompatible + injectionEsomeprazole sodium
Incompatible + injectionFamotidine
Incompatible + injectionFilgrastim
Incompatible + injectionGentamicin sulfate
Incompatible + injectionHaloperidol lactate
Incompatible + injectionHydromorphone hydrochloride
Incompatible + injectionHydroxyzine dihydrochloride
Incompatible + injectionInsulin
Incompatible + injectionInsulin lyspro
Incompatible + injectionLabetalol hydrochloride
Incompatible + injectionLevofloxacine
Incompatible + injectionLidocaine hydrochloride
Incompatible + injectionMagnesium sulfate
Incompatible + injectionMetoclopramide hydrochloride
Incompatible + injectionMidazolam hydrochloride
Incompatible + injectionMilrinone lactate
Incompatible + injectionMorphine sulfate
Incompatible + injectionMoxifloxacin
Incompatible + injectionOndansetron hydrochloride
Incompatible + injectionPantoprazole sodium
Incompatible + injectionPethidine hydrochloride
Incompatible + injectionPotassium phosphate
Incompatible + injectionPromethazine hydrochloride
Incompatible + injectionRemifentanil hydrochloride
Incompatible + injectionSodium Phosphate
Incompatible + injectionTobramycin sulfate
injectionCiprofloxacin lactate Antibiotic
Incompatible + injectionCeftobiprole medocaril sodium
injectionCisatracurium besylate Curarimimetic
Incompatible + injectionCeftobiprole medocaril sodium
injectionDiazepam Anxiolytic
Incompatible + injectionCeftobiprole medocaril sodium
injectionDiltiazem hydrochloride Anti-arrhythmic
Incompatible + injectionCeftobiprole medocaril sodium
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Incompatible + injectionCeftobiprole medocaril sodium
injectionDobutamine hydrochloride Cardiotonic
Incompatible + injectionCeftobiprole medocaril sodium
injectionDopamine hydrochloride Cardiotonic
Incompatible + injectionCeftobiprole medocaril sodium
injectionEsomeprazole sodium Proton pump inhibitor
Incompatible + injectionCeftobiprole medocaril sodium
injectionFamotidine Antihistamine (H2)
Incompatible + injectionCeftobiprole medocaril sodium
injectionFilgrastim Various
Incompatible + injectionCeftobiprole medocaril sodium
injectionGentamicin sulfate Antibiotic
Incompatible + injectionCeftobiprole medocaril sodium
injectionHaloperidol lactate Neuroleptic
Incompatible + injectionCeftobiprole medocaril sodium
injectionHydromorphone hydrochloride Analgesic
Incompatible + injectionCeftobiprole medocaril sodium
injectionHydroxyzine dihydrochloride Anxiolytic
Incompatible + injectionCeftobiprole medocaril sodium
injectionInsulin Glucose-lowering
Incompatible + injectionCeftobiprole medocaril sodium
injectionInsulin lyspro Glucose-lowering
Incompatible + injectionCeftobiprole medocaril sodium
injectionLabetalol hydrochloride Beta-blocker
Incompatible + injectionCeftobiprole medocaril sodium
injectionLevofloxacine Antibiotic
Incompatible + injectionCeftobiprole medocaril sodium
injectionLidocaine hydrochloride Local anesthetic
Incompatible + injectionCeftobiprole medocaril sodium
injectionMagnesium sulfate Electrolyte
Incompatible + injectionCeftobiprole medocaril sodium
injectionMetoclopramide hydrochloride Antiemetic
Incompatible + injectionCeftobiprole medocaril sodium
injectionMidazolam hydrochloride Anxiolytic
Incompatible + injectionCeftobiprole medocaril sodium
injectionMilrinone lactate Cardiotonic
Incompatible + injectionCeftobiprole medocaril sodium
injectionMorphine sulfate Analgesic
Incompatible + injectionCeftobiprole medocaril sodium
injectionMoxifloxacin Antibiotic
Incompatible + injectionCeftobiprole medocaril sodium
injectionOndansetron hydrochloride Antiemetic
Incompatible + injectionCeftobiprole medocaril sodium
injectionPantoprazole sodium Proton pump inhibitor
Incompatible + injectionCeftobiprole medocaril sodium
injectionPethidine hydrochloride Analgesic
Incompatible + injectionCeftobiprole medocaril sodium
injectionPotassium phosphate Electrolyte
Incompatible + injectionCeftobiprole medocaril sodium
injectionPromethazine hydrochloride Antihistamine (H1)
Incompatible + injectionCeftobiprole medocaril sodium
injectionRemifentanil hydrochloride Analgesic
Incompatible + injectionCeftobiprole medocaril sodium
injectionSodium Phosphate Electrolyte
Incompatible + injectionCeftobiprole medocaril sodium
injectionTobramycin sulfate Antibiotic
Incompatible + injectionCeftobiprole medocaril sodium

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