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References   References 4845  
Type : Journal
Web link : https://doi.org/ 10.3390/pharmaceutics16030419
Research teams : Bentley - Curtin Medical School, Curtin University, Bentley, WA, Australia
Authors : De Silva D.T.N, Strunk T, Petrovski M, Page-Sharp M, Moore B.R, Batty K.T.
Title : The Physicochemical Compatibility of Sildenafil Injection with Parenteral Medications Used in Neonatal Intensive Care Settings.
Reference : Pharmaceutics ;1 6, 419. 2024
Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
List of drugs
injectionAciclovir sodium Antiviral
Incompatible 5 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
injectionAlprostadil Vasodilator
Compatible 20 µg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionAmoxicillin sodium Antibiotic
Compatible 100 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 100 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 50 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionAmphotericin B Antifungal
Incompatible 0,1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 0.1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionAmphotericin B liposomale Antifungal
Compatible 2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionAmpicillin sodium Antibiotic
Compatible 100 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 100 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 50 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionCaffeine Respiratory stimulant
Compatible 10 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionCaffeine citrate Respiratory stimulant
Compatible 20 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionCalcium gluconate Electrolyte
Incompatible 100 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionCefotaxime sodium Antibiotic
Compatible 100 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionClonidine hydrochloride Antihypertensive
Compatible 0.002 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionCloxacillin sodium Antibiotic
Compatible 100 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionDexmedetomidine Sympathomimetic
Compatible 1 µg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 7.2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 7.2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 64 µg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionFlucloxacillin sodium Antibiotic
Incompatible + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 50 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Incompatible 0.2 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 0,2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 10 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 2 UI/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 100 UI/ml + injectionSildenafil citrate 0,06 mg/ml + Glucose 5%
Compatible 100 UI/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + injectionSildenafil citrate 0,06 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionIbuprofen lysinate Anti-inflammatory
Compatible 4 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 4 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionIndomethacin sodium trihydrate Anti-inflammatory
Compatible 0.2 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 0,2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionInsulin Glucose-lowering
Compatible 0.2 UI/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionLevetiracetam Antiepileptic
Compatible 5 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionLinezolid Antibiotic
Compatible 2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionMeropenem Antibiotic
Incompatible 25 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 25 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 50 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 50 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 0.5 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 0.12 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionMilrinone lactate Cardiotonic
Compatible 0.4 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionMorphine hydrochloride Analgesic
Compatible 0.2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 0.2 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 64 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 0.064 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionParacetamol Analgesic
Compatible 10 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionPenicillin G sodium Antibiotic
Compatible + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 100 MUI/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionPhenobarbital sodium Antiepileptic
Incompatible 20 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 200 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionRifampicin Antibiotic
Compatible 6 mg/ml + injectionSildenafil citrate 0.06 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionSildenafil citrate 0,6 mg/ml
injectionSildenafil citrate Vasodilator
Incompatible 0,6 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 0,6 mg/ml + injectionAciclovir sodium 5 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionAciclovir sodium 5 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionAlprostadil 20 µg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionAmoxicillin sodium 100 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionAmoxicillin sodium 100 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionAmoxicillin sodium 50 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionAmphotericin B 0.1 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionAmphotericin B 0,1 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionAmphotericin B liposomale 2 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionAmpicillin sodium 100 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionAmpicillin sodium 100 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionAmpicillin sodium 50 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionCaffeine 10 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionCaffeine citrate 20 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionCalcium gluconate 100 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionCefotaxime sodium 100 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionClonidine hydrochloride 0.002 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionCloxacillin sodium 100 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionDexmedetomidine 1 µg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionDobutamine hydrochloride 7.2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionDopamine hydrochloride 7.2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionEpinephrine hydrochloride 64 µg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionFentanyl citrate 50 µg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionFlucloxacillin sodium 50 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionFlucloxacillin sodium + Glucose 5%
Compatible 0,6 mg/ml + injectionFluconazole 2 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionFurosemide 1 mg/ml + Glucose 5%
Incompatible 0.06 mg/ml + injectionFurosemide 1 mg/ml + Glucose 5%
Incompatible 0.06 mg/ml + injectionFurosemide 0.2 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionFurosemide 0,2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionGentamicin sulfate 10 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionHeparin sodium 2 UI/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0,06 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionHydrocortisone sodium succinate 10 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionHydrocortisone sodium succinate 10 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0,06 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionIbuprofen lysinate 4 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionIbuprofen lysinate 4 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionIndomethacin sodium trihydrate 0,2 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionIndomethacin sodium trihydrate 0.2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionInsulin 0.2 UI/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionLevetiracetam 5 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionLinezolid 2 mg/ml + Glucose 5%
Incompatible 0.06 mg/ml + injectionMeropenem 25 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionMeropenem 25 mg/ml + Glucose 5%
Incompatible 0.06 mg/ml + injectionMeropenem 50 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionMeropenem 50 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMidazolam hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMidazolam hydrochloride 0.12 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMilrinone lactate 0.4 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMorphine hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionMorphine sulfate 0.2 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionNorepinephrine bitartrate 64 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionNorepinephrine bitartrate 0.064 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionParacetamol 10 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionPenicillin G sodium 100 MUI/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionPenicillin G sodium + Glucose 5%
Incompatible 0,6 mg/ml + injectionPhenobarbital sodium 20 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionPhenobarbital sodium 20 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionPiperacillin sodium / tazobactam 200 mg/ml + Glucose 5%
Compatible 0.06 mg/ml + injectionRifampicin 6 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionRifampicin 6 mg/ml
Incompatible 0,6 mg/ml + injectionSodium bicarbonate 42 mg/ml + Glucose 5%
Incompatible 0,6 mg/ml + injectionSodium bicarbonate 42 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 0,6 mg/ml + injectionVecuronium bromide 1 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Incompatible 42 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
Incompatible 42 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
injectionVecuronium bromide Curarimimetic
Compatible 1 mg/ml + injectionSildenafil citrate 0,6 mg/ml + Glucose 5%
  Mentions Légales