Last update :
23/11/2022
Antihypertensive   Clonidine hydrochloride  
Injection
Oral solution Paper bag
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Catapres Australia, Great Britain, Ireland, New Zealand
Catapresan Austria, Finland, Germany, Greece, Italy, Netherlands, Spain, Sweden, Switzerland, Venezuela
Catapressan Belgium, France, Luxembourg, Morocco, Tunisia
Clonidin Brazil, Germany
Clonidina Argentina, Chile, Spain, Venezuela
Clonipres Venezuela
Haemiton Germany
Lowpres Venezuela
Paracefan Germany
Compatibility   Injection   Compatibility : Clonidine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Aminophylline 0,9 mg/ml
Sodium chloride 0,9% 2018
Immediate precipitation Incompatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Amiodarone hydrochloride 6 & 24 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0,2 mg/ml
Injection Baclofen 1 mg/ml
Sodium chloride 0,9% 1601
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Cisatracurium besylate 5 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Clonazepam 0.2 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0.0024 mg/ml
Injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Diclofenac 3 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Dihydralazine mesilate 0.5 & 1.5 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Dobutamine hydrochloride 2 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Dobutamine hydrochloride 8 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Dopamine hydrochloride 8 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Dopamine hydrochloride 2 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Epinephrine hydrochloride 20 µg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Esomeprazole sodium 0.32 mg/ml
Sodium chloride 0,9% 1506
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Fentanyl citrate 50 µg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Furosemide 2 mg/ml
Sodium chloride 0,9% 1506
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Furosemide 1.2 & 10 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Haloperidol lactate 0.5 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Heparin sodium 50 UI/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Insulin 1 UI/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Clonidine hydrochloride 0,0125 mg/ml
Injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Isoprenaline hydrochloride 0,004 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Ketamine hydrochloride 25 mg/ml
Sodium chloride 0,9% 3705
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Labetalol hydrochloride 1 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0,0084 mg/ml
Injection Levobupivacaine hydrochloride
Sodium chloride 0,9% 3507
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Levosimendan 0.025 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Lorazepam 0.33 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Lormetazepam 0.12 mg/ml
Sodium chloride 0,9% 3705
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Magnesium sulfate 9,6 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Metamizol sodium 50 & 100 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Methadone hydrochloride 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1506
Immediate turbidity Incompatible
Injection Clonidine hydrochloride 0,0125 mg/ml
Injection Methylprednisolone sodium succinate 0,2 mg/ml
Sodium chloride 0,9% 4698
Color change after 24 hours Incompatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Midazolam hydrochloride 5 mg/ml
None 186
Compatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Midazolam hydrochloride 3.6 mg/ml
Sodium chloride 0,9% 3705
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Midazolam hydrochloride 1 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Midazolam hydrochloride 2.1 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Milrinone lactate 0.2 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Morphine hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Clonidine hydrochloride 0.25 mg/ml
Injection Morphine sulfate 5 mg/ml
Sodium chloride 0,9% 1708
Compatible
Injection Clonidine hydrochloride 0,05 & 1,84 mg/ml
Injection Morphine sulfate 2 & 20 mg/ml
Sodium chloride 0,9% 1869
Compatible
Injection Clonidine hydrochloride 4 mg/ml
Injection Morphine sulfate 50 mg/ml
Water for Injection 1708
Compatible
Injection Clonidine hydrochloride 0,0125 mg/ml
Injection Mycophenolate mofetil 10 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Nimodipine 0.2 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Nitroglycerin 0,4 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Norepinephrine bitartrate 0,02 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.0075 mg/ml
Injection Pantoprazole sodium 0.32 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Clonidine hydrochloride 0,001 mg/ml
Injection Pentoxifyllin 5 mg/ml
Sodium chloride 0,9% 4538
Compatible
Injection Clonidine hydrochloride 0.003 mg/ml
Injection Pethidine hydrochloride 8 mg/ml
Sodium chloride 0,9% 2184
Compatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Piritramide 1 mg/ml
Sodium chloride 0,9% 3705
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Potassium chloride 1 mEq/l
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Potassium chloride 40 mEq/l
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.001 >> 0.015 mg/ml
Injection Propofol 1.8 >> 18.2 mg/ml
None 4011
Compatible
Injection Clonidine hydrochloride 0,005 >> 0,05 mg/ml
Injection Ropivacain hydrochloride 1 - 2 mg/ml
1516
Compatible
Injection Clonidine hydrochloride 0.005 & 0.05 mg/ml
Injection Ropivacain hydrochloride 1 & 2 mg/ml
Sodium chloride 0,9% 1665
Compatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Sodium oxybate 200 mg/ml
Sodium chloride 0,9% 3705
Chemical instability Incompatible
Injection Clonidine hydrochloride 0.015 mg/ml
Injection Sufentanil citrate 0.03 mg/ml
Sodium chloride 0,9% 3705
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Theophylline 1 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0,0125 mg/ml
Injection Thiamine hydrochloride 1 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Clonidine hydrochloride 0,0125 mg/ml
Injection Urapidil 5 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Urapidil 2 & 5 mg/ml
4130
Compatible
Injection Clonidine hydrochloride 0.012 mg/ml
Injection Valproic acid 16 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Clonidine hydrochloride 0,018 mg/ml
Injection Verapamil hydrochloride 2,5 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
Injection Verapamil hydrochloride 1 mg/ml
4130

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