Last update :
03/02/2023
Antiepileptic   Phenobarbital sodium  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Carbital Brazil
Fenemal Sweden
Fenobarb India
Fenobarbital Argentina, Colombia, Ecuador
Gardenal Brazil, France, Great Britain, India, Morocco, Tunisia, Venezuela
Luminal Germany, Iran, Spain
Luminale Italy
Luminalum Poland
Phenobarbital sodium Canada, Great Britain
Sominaletta Egypt
Compatibility   Injection   Compatibility : Phenobarbital sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Phenobarbital sodium 5 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Phenobarbital sodium 5 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Immediate precipitation Incompatible
Injection Phenobarbital sodium 64 mg/ml
Parenteral nutrition (binary mixture) 3379
Immediate instability of the emulsion Incompatible
Injection Phenobarbital sodium 5 mg/ml
Parenteral nutrition (with lipids) 1415
Immediate turbidity Incompatible
Injection Phenobarbital sodium 5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Atracurium besylate
3676
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Chlorpromazine hydrochloride
3596
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Clindamycin phosphate
3526
Compatible
Injection Phenobarbital sodium 10 mg/ml
Injection Doxapram hydrochloride 2 mg/ml
Glucose 5% 1802
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Droperidol
4009
Compatible
Injection Phenobarbital sodium 0.32 mg/ml
Injection Enalaprilate 1.25 mg/ml
NaCl 0,9% or Glucose 5% 201
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Erythromycin lactobionate
3674
Immediate precipitation Incompatible
Injection Phenobarbital sodium
Injection Esketamine
4700
Compatible
Injection Phenobarbital sodium 2 mg/ml
Injection Fentanyl citrate 25 µg/ml
Glucose 5% 1974
Compatible
Injection Phenobarbital sodium 65 mg/ml
Injection Fosphenytoin sodium 5 mg/ml
Sodium chloride 0,9% 1412
Compatible
Injection Phenobarbital sodium 2 mg/ml
Injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 1974
Immediate precipitation Incompatible
Injection Phenobarbital sodium 120 mg/ml
Injection Hydromorphone hydrochloride 2 >> 40 mg/ml
Glucose 5% 226
Compatible
Injection Phenobarbital sodium 30 mg/ml
Injection Ibuprofen lysinate 10 mg/ml
Water for Injection 4419
Compatible
Injection Phenobarbital sodium 130 mg/ml
Injection Ibuprofen lysinate 10 mg/ml
Water for Injection 4419
Immediate precipitation Incompatible
Injection Phenobarbital sodium
Injection Ketamine hydrochloride
3501
Immediate precipitation Incompatible
Injection Phenobarbital sodium 5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Phenobarbital sodium 130 mg/ml
Injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
Injection Phenobarbital sodium 5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Phenobarbital sodium 0.2 mg/ml
Injection Meropenem 1 & 20 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Phenobarbital sodium 0.32 mg/ml
Injection Meropenem 1 & 50 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Phenobarbital sodium 2 mg/ml
Injection Methadone hydrochloride 1 mg/ml
Glucose 5% 1974
Compatible
Injection Phenobarbital sodium 2 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Morphine sulfate
3531
Compatible
Injection Phenobarbital sodium 60 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Norepinephrine bitartrate
642
Precipitation after 4 hours Incompatible
Injection Phenobarbital sodium
Injection Pantoprazole sodium
2090
Precipitation after 4 hours Incompatible
Injection Phenobarbital sodium 100 mg/ml
Injection Paracetamol 10 mg/ml
Glucose 5% 4435
Compatible
Injection Phenobarbital sodium 20 mg/ml
Injection Pentoxifyllin 5 mg/ml
Sodium chloride 0,9% 4543
Immediate turbidity Incompatible
Injection Phenobarbital sodium
Injection Pethidine hydrochloride
3525
Compatible
Injection Phenobarbital sodium 5 mg/ml
Injection Propofol 10 mg/ml
None 300
Immediate instability of the emulsion Incompatible
Injection Phenobarbital sodium 65 mg/ml
Injection Propofol
660
Immediate turbidity Incompatible
Injection Phenobarbital sodium 120 mg/ml
Injection Ranitidine hydrochloride 25 mg/ml
None 58
Unspecified incompatibility Incompatible
Injection Phenobarbital sodium
Injection Suxamethonium chloride
3631
Compatible
Injection Phenobarbital sodium 0.26 mg/ml
Injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057

  Mentions Légales