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References   References 3152  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/67/19/1640
Research teams : Minneapolis - University of Minnesotta, College of Pharmacy
Authors : Kumar A, Mann HJ.
Title : Visual compatibility of oritavancin diphosphate with selected coadministered drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 67: 1640-1644. 2010
Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only
List of drugs
injectionAminophylline Various
Incompatible 1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionAmphotericin B Antifungal
Incompatible 0.1 mg/ml + injectionOritavancin 0.8>>2 mg/ml + Glucose 5%
injectionAztreonam Antibiotic
Incompatible 20 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionBumetanide Diuretic
Incompatible 0.1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 12 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionClindamycin phosphate Antibiotic
Incompatible 12 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionCo-trimoxazole Antibiotic
Incompatible 0.8/4 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionDexmedetomidine Sympathomimetic
Compatible 4 µg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 40 µg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 0.2 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Incompatible 5 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionHaloperidol lactate Neuroleptic
Compatible 1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + injectionOritavancin 0.8 >>1.2 mg/ml + Glucose 5%
Incompatible 100 UI/ml + injectionOritavancin 2 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionInsulin Glucose-lowering
Compatible 1 UI/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionLorazepam Anxiolytic
Compatible 1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionMeropenem Antibiotic
Incompatible 10 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionOritavancin 0.8 >>1.2 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionOritavancin 2 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionNitroprusside sodium Vasodilator
Incompatible 0.4 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.12 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionOritavancin Antibiotic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 0.8 >>2 mg/ml + injectionAminophylline 1 mg/ml + Glucose 5%
Incompatible 0.8>>2 mg/ml + injectionAmphotericin B 0.1 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionAztreonam 20 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionBumetanide 0.1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionCalcium gluconate 40 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionClindamycin phosphate 12 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionCo-trimoxazole 0.8/4 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionDexmedetomidine 4 µg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionEpinephrine hydrochloride 40 µg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionFamotidine 0.2 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionFentanyl citrate 50 µg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionFluconazole 2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionFurosemide 5 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionHaloperidol lactate 1 mg/ml + Glucose 5%
Incompatible 0.8 >>1.2 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Incompatible 2 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionLorazepam 1 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionMeropenem 10 mg/ml + Glucose 5%
Incompatible 2 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.8 >>1.2 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionNitroglycerin 0.4 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionNitroprusside sodium 0.4 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionNorepinephrine bitartrate 0.12 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionPancuronium bromide 0.1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionPhenylephrine hydrochloride 0.2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionPhenytoin sodium 6 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionPotassium chloride 0.2 mEq/l + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + injectionTobramycin sulfate 5 mg/ml + Glucose 5%
injectionPancuronium bromide Curarimimetic
Compatible 0.1 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionPhenylephrine hydrochloride Sympathomimetic
Compatible 0.2 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 6 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 0.2 mEq/l + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + injectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
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