Dernière mise à jour :
19/11/2024
Bibliographie   Bibliographie 249  
Type : Revue
Lien Internet : http://www.ajhp.org/cgi/content/abstract/53/9/1041

Equipes de recherche : Houston - M.D.Anderson Cancer Center
Auteurs : Trissel LA, Martinez JF.
Titre : Compatibility of thiotepa (lyophilized) with selected drugs during simulated Y-site administration.
Référence : Am J Health-Syst Pharm ; 53: 1041-1045. 1996

Niveau de preuve : 
Non coté
Stabilité physique : 
Stabilité chimique : 
Autres méthodes : 
Commentaires : 
Non coté : étude de compatibilité seule

Liste des molécules
injectableAciclovir sodium Antiviral
Compatible 7 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableAmikacin sulfate Antibiotique
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableAminophylline Divers
Compatible 2.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableAmphotericin B Antifongique
Compatible 0.6 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableAmpicillin sodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableAmpicillin sodium - sulbactam sodium Antibiotique
Compatible 20/10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableAztreonam Antibiotique
Compatible 40 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableBleomycin sulfate Anticancéreux
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableBumetanide Diurétique
Compatible 0.04 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableBuprenorphine hydrochloride Antalgique
Compatible 0.04 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableButorphanol tartrate Antalgique
Compatible 0.04 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCalcium gluconate électrolyte
Compatible 40 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCarboplatin Anticancéreux
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCarmustine Anticancéreux
Compatible 1.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCefazolin sodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCefonicid sodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCefoperazone sodium Antibiotique
Compatible 40 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCefotaxime sodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCefoxitin sodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCeftazidime Antibiotique
Compatible 40 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCeftizoxime sodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCeftriaxone disodium Antibiotique
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCefuroxime sodium Antibiotique
Compatible 30 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableChlorpromazine hydrochloride Anxiolytique
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCimetidine hydrochloride Antihistaminique H2
Compatible 12 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCiprofloxacin lactate Antibiotique
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCisplatin Anticancéreux
Incompatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableClindamycin phosphate Antibiotique
Compatible 10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCo-trimoxazole Antibiotique
Compatible 0.8/4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCyclophosphamide Anticancéreux
Compatible 10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableCytarabine Anticancéreux
Compatible 50 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDacarbazine Anticancéreux
Compatible 4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDactinomycin Anticancéreux
Compatible 10 µg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDaunorubicin hydrochloride Anticancéreux
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDexamethasone sodium phosphate Antiinflammatoire
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDiphenhydramine hydrochloride Antihistaminique H1
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDobutamine hydrochloride Cardiotonique
Compatible 4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDopamine hydrochloride Cardiotonique
Compatible 3.2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDoxorubicin hydrochloride Anticancéreux
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDoxycycline hyclate Antibiotique
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableDroperidol Neuroleptique
Compatible 0.4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableEnalaprilate Antihypertenseur
Compatible 0.1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableEtoposide Anticancéreux
Compatible 0.4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFamotidine Antihistaminique H2
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFloxuridine Anticancéreux
Compatible 3 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFluconazole Antifongique
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFludarabine phosphate Anticancéreux
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFluorouracil Anticancéreux
Compatible 16 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFolinate calcium Cytoprotecteur
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableFurosemide Diurétique
Compatible 3 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableGallium nitrate Hypocalcémiant
Compatible 0.4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableGanciclovir sodium Antiviral
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableGentamicin sulfate Antibiotique
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableGranisetron hydrochloride Antiémétique
Compatible 0.05 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableHaloperidol lactate Neuroleptique
Compatible 0.2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableHydrocortisone sodium succinate Antiinflammatoire
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableHydromorphone hydrochloride Antalgique
Compatible 0.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableHydroxyzine dihydrochloride Anxiolytique
Compatible 4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableIdarubicin hydrochloride Anticancéreux
Compatible 0.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableIfosfamide Anticancéreux
Compatible 25 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableImipenem - cilastatin sodium Antibiotique
Compatible 10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableLorazepam Anxiolytique
Compatible 0.1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMagnesium sulfate électrolyte
Compatible 100 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMannitol Divers
Compatible 150 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMesna Cytoprotecteur
Compatible 10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMethotrexate sodium Anticancéreux
Compatible 15 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMethylprednisolone sodium succinate Antiinflammatoire
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMetoclopramide hydrochloride Antiémétique
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMetronidazole Antiparasitaire
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMinocycline hydrochloride Antibiotique
Incompatible 0.2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMitomycin Anticancéreux
Compatible 0.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMitoxantrone dihydrochloride Anticancéreux
Compatible 0.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableMorphine sulfate Antalgique
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableNalbuphine hydrochloride Antidote
Compatible 10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableNetilmicin sulfate Antibiotique
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableOfloxacin Antibiotique
Compatible 4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableOndansetron hydrochloride Antiémétique
Compatible 1 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectablePaclitaxel Anticancéreux
Compatible 0.6 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectablePethidine hydrochloride Antalgique
Compatible 4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectablePiperacillin sodium Antibiotique
Compatible 40 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectablePotassium chloride électrolyte
Compatible 100 mEq/l + injectableThiotepa 1 mg/ml + Glucose 5%
injectableProchlorperazine edysilate Neuroleptique
Compatible 0.5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectablePromethazine hydrochloride Antihistaminique H1
Compatible 2 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableRanitidine hydrochloride Antihistaminique H2
Compatible 20 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableSodium bicarbonate électrolyte
Compatible 84 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableStreptozocin Anticancéreux
Compatible 40 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableThiotepa Anticancéreux
Compatible 1 mg/ml + Nutrition parentérale (mélange binaire)
Compatible 1 mg/ml + injectableAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableAminophylline 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableAmphotericin B 0.6 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableAmpicillin sodium - sulbactam sodium 20/10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableAztreonam 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableBleomycin sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableBumetanide 0.04 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableBuprenorphine hydrochloride 0.04 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableButorphanol tartrate 0.04 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCalcium gluconate 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCarboplatin 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCarmustine 1.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCefonicid sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCefoperazone sodium 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCeftazidime 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCeftriaxone disodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCiprofloxacin lactate 1 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectableCisplatin 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCo-trimoxazole 0.8/4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCyclophosphamide 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableCytarabine 50 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDacarbazine 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDactinomycin 10 µg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDaunorubicin hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableDroperidol 0.4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableEnalaprilate 0.1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableEtoposide 0.4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFamotidine 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFloxuridine 3 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFluconazole 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFludarabine phosphate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFluorouracil 16 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFolinate calcium 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableFurosemide 3 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableGallium nitrate 0.4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableHeparin sodium 100 UI/ml + Glucose 5%
Compatible 1 mg/ml + injectableHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableHydroxyzine dihydrochloride 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableIdarubicin hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableIfosfamide 25 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableImipenem - cilastatin sodium 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableLorazepam 0.1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMagnesium sulfate 100 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMannitol 150 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMesna 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMethotrexate sodium 15 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMetronidazole 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectableMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMitomycin 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMitoxantrone dihydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableNalbuphine hydrochloride 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableNetilmicin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableOfloxacin 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableOndansetron hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectablePaclitaxel 0.6 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectablePethidine hydrochloride 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectablePiperacillin sodium 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectablePotassium chloride 100 mEq/l + Glucose 5%
Compatible 1 mg/ml + injectableProchlorperazine edysilate 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectablePromethazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableRanitidine hydrochloride 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableStreptozocin 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableTicarcillin / clavulanic acid 31 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableVinblastine sulfate 0.12 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableVincristine sulfate 0.05 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectableZidovudine 4 mg/ml + Glucose 5%
injectableTicarcillin / clavulanic acid Antibiotique
Compatible 31 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableTobramycin sulfate Antibiotique
Compatible 5 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableVancomycin hydrochloride Antibiotique
Compatible 10 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableVinblastine sulfate Anticancéreux
Compatible 0.12 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableVincristine sulfate Anticancéreux
Compatible 0.05 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%
injectableZidovudine Antiviral
Compatible 4 mg/ml + injectableThiotepa 1 mg/ml + Glucose 5%

  Mentions Légales