Last update :
19/11/2024
Antibiotic   Linezolid  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Bogadril Mexico, Republic of South Africa
Entavar India
Linezolid Argentina, Canada, Ecuador, Germany, Peru, Romania, Spain, Switzerland
Linezolida Chile
Linezolide Switzerland
Linezone Turkey
Linsyn Peru
Litasina Chile, Peru
Litrecan Argentina, Chile, Peru
Milbrar Mexico
Nodizil Turkey
Pneumolid Romania
Renyvozon Mexico
Tymbro Peru
Voxazoldin Egypt
Xolid India
Zizolid Turkey
Zyvox Argentina, Australia, Chile, Egypt, Great Britain, Hungary, Ireland, Malaysia, New Zealand, United States of America
Zyvoxam Canada, Mexico
Zyvoxid Austria, Belgium, Colombia, Denmark, Ecuador, Finland, France, Germany, Hungary, Iceland, Italy, Netherlands, Norway, Poland, Portugal, Romania, Spain, Sweden, Switzerland, Turkey, Venezuela
Compatibility   injection   Compatibility : Linezolid              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Linezolid 2 mg/ml
injection Aciclovir sodium 7 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Alfentanil hydrochloride 500 µg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Amikacin sulfate 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Aminophylline 2.5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Unspecified incompatibility Incompatible
injection Linezolid
injection Amphotericin B
3560
Immediate precipitation Incompatible
injection Linezolid 2 mg/ml
injection Amphotericin B 0.6 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ampicillin sodium 20 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ampicillin sodium - sulbactam sodium 20/10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Compatible
injection Linezolid 2 mg/ml
injection Aztreonam 40 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Aztreonam 20 mg/ml
None 1658
Compatible
injection Linezolid 2 mg/ml
injection Bretylium tosilate 50 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Buprenorphine hydrochloride 0.04 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Butorphanol tartrate 0.04 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Linezolid 2 mg/ml
injection Caffeine 10 mg/ml
4837
Compatible
injection Linezolid 2 mg/ml
injection Caffeine 10 mg/ml
Sodium chloride 0,9% 4837
Compatible
injection Linezolid 2 mg/ml
injection Caffeine citrate 20 mg/ml
4837
Compatible
injection Linezolid 2 mg/ml
injection Calcium gluconate 40 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Carboplatin 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Compatible
injection Linezolid 2 mg/ml
injection Caspofungin acetate 0.5 mg/ml
Sodium chloride 0,9% 2233
Compatible
injection Linezolid 2 mg/ml
injection Cefazolin sodium 10 mg/ml
None 1659
Compatible
injection Linezolid 2 mg/ml
injection Cefazolin sodium 20 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
injection Linezolid 2 mg/ml
injection Cefonicid sodium 20 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Cefoperazone sodium 40 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Cefoxitin sodium 20 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ceftazidime 40 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ceftazidime 20 mg/ml
None 1659
Compatible
injection Linezolid 2 mg/ml
injection Ceftizoxime sodium 20 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Chemical instability Incompatible
injection Linezolid 2 mg/ml
injection Ceftriaxone disodium 10 mg/ml
None 1659
Compatible
injection Linezolid 2 mg/ml
injection Ceftriaxone disodium 20 mg/ml
None 1925
Compatible
injection Linezolid 0,48 mg/ml
Parenteral nutrition (with lipids) 4461
Unspecified incompatibility Incompatible
injection Linezolid
injection Ceftriaxone disodium
3560
Compatible
injection Linezolid 2 mg/ml
injection Cefuroxime sodium 30 mg/ml
None 1925
Immediate turbidity Incompatible
injection Linezolid 2 mg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
None 1925
Unspecified incompatibility Incompatible
injection Linezolid
injection Chlorpromazine hydrochloride
3560
Compatible
injection Linezolid 2 mg/ml
injection Ciclosporin 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Cimetidine hydrochloride 12 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ciprofloxacin lactate 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ciprofloxacin lactate 4 mg/ml
None 1668
Compatible
injection Linezolid 2 mg/ml
injection Cisatracurium besylate 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Cisplatin 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Clindamycin phosphate 10 mg/ml
None 1925
Immediate precipitation Incompatible
injection Linezolid 2 mg/ml
injection Co-trimoxazole 0.8/4 mg/ml
None 1607
Compatible
injection Linezolid 2 mg/ml
injection Co-trimoxazole 0.8/4 mg/ml
None 1925
Unspecified incompatibility Incompatible
injection Linezolid
injection Co-trimoxazole
3560
Compatible
injection Linezolid 2 mg/ml
injection Colistin mesilate sodium 1.5 mg/ml
Sodium chloride 0,9% 3997
Compatible
injection Linezolid 2 mg/ml
injection Cyclophosphamide 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Cytarabine 50 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Dexamethasone sodium phosphate 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Immediate turbidity Incompatible
injection Linezolid 2 mg/ml
injection Diazepam 5 mg/ml
None 1925
Unspecified incompatibility Incompatible
injection Linezolid
injection Diazepam
3560
Compatible
injection Linezolid 2 mg/ml
injection Digoxin 250 µg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Diphenhydramine hydrochloride 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Dobutamine hydrochloride 4 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Dopamine hydrochloride 3.2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
injection Linezolid 2 mg/ml
injection Doxorubicin hydrochloride 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Doxycycline hyclate 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Droperidol 0.4 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Enalaprilate 0.1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Eravacycline 0,6 mg/ml
Sodium chloride 0,9% 4434
Compatible
injection Linezolid 2 mg/ml
injection Erythromycin lactobionate 5 mg/ml
None 1925
Chemical instability Incompatible
injection Linezolid 2 mg/ml
injection Erythromycin lactobionate 5 mg/ml
None 1607
Unspecified incompatibility Incompatible
injection Linezolid
injection Erythromycin lactobionate
3560
Compatible
injection Linezolid 2 mg/ml
injection Esmolol hydrochloride 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Etoposide phosphate 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Famotidine 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Linezolid 2 mg/ml
injection Fentanyl citrate 50 µg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Fluconazole 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Fluorouracil 16 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Folinate calcium 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Compatible
injection Linezolid 2 mg/ml
injection Furosemide 3 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ganciclovir sodium 20 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Gemcitabine hydrochloride 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Gentamicin sulfate 5 mg/ml
None 1925
Compatible
injection Linezolid 1,80 mg/ml
injection Gentamicin sulfate 0,75 mg/ml
2353
Compatible
injection Linezolid 2 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Haloperidol lactate 0.2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Heparin sodium 1000 UI/ml
None 1925
Compatible
injection Linezolid 0.2 >> 1.92 mg/ml
injection Heparin sodium 10 >> 10000 UI/ml
Sodium chloride 0,9% 2057
Compatible
injection Linezolid 2 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Hydroxyzine dihydrochloride 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ifosfamide 25 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Imipenem - cilastatin sodium 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Insulin 1 UI/ml
Sodium chloride 0,9% 4254
Compatible
injection Linezolid 2 mg/ml
injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Compatible
injection Linezolid 2 mg/ml
injection Labetalol hydrochloride 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Levofloxacine 5 mg/ml
None 1668
Compatible
injection Linezolid 2 mg/ml
injection Levofloxacine 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Lidocaine hydrochloride 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Lorazepam 0.1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Magnesium sulfate 100 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Mannitol 150 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Meropenem 2.5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Linezolid 2 mg/ml
injection Mesna 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Methotrexate sodium 15 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Metoclopramide hydrochloride 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Metronidazole 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Midazolam hydrochloride 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Minocycline hydrochloride 0.2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Mitoxantrone dihydrochloride 0.5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Morphine sulfate 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Nalbuphine hydrochloride 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Netilmicin sulfate 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Nicardipine hydrochloride 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Nitroglycerin 0.4 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ofloxacin 4 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ofloxacin 4 mg/ml
None 1668
Compatible
injection Linezolid 2 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Paclitaxel 0.6 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Paracetamol 10 mg/ml
4742
Unspecified incompatibility Incompatible
injection Linezolid
injection Pentamidine isetionate
3560
Precipitation after 1 hour Incompatible
injection Linezolid 2 mg/ml
injection Pentamidine isetionate 6 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Pentobarbital sodium 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Pentoxifyllin 5 mg/ml
Sodium chloride 0,9% 4543
Compatible
injection Linezolid 2 mg/ml
injection Pethidine hydrochloride 4 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Phenobarbital sodium 5 mg/ml
None 1925
Immediate precipitation Incompatible
injection Linezolid 2 mg/ml
injection Phenytoin sodium 50 mg/ml
None 1925
Unspecified incompatibility Incompatible
injection Linezolid
injection Phenytoin sodium
3560
Compatible
injection Linezolid 2 mg/ml
injection Piperacillin sodium 40 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Piperacillin sodium 30 mg/ml
None 1658
Compatible
injection Linezolid 2 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
None 1925
Compatible
injection Linezolid 0,48 mg/ml
Parenteral nutrition (binary mixture) 4461
Compatible
injection Linezolid 2 mg/ml
injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
injection Linezolid 2 mg/ml
Ringer’s lactate solution 4603
Compatible
injection Linezolid 2 mg/ml
injection Potassium chloride 100 mEq/l
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Prochlorperazine edysilate 0.5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Promethazine hydrochloride 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Propranolol hydrochloride 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Ranitidine hydrochloride 2 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Remifentanil hydrochloride 500 µg/ml
None 1925
Compatible
injection Linezolid 1 mg/ml
injection Sodium bicarbonate 40 mg/ml
None 3122
Compatible
injection Linezolid 2 mg/ml
injection Sodium bicarbonate 84 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Sufentanil citrate 0.05 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Compatible
injection Linezolid 2 mg/ml
injection Theophylline 4 mg/ml
None 1925
Compatible
injection Linezolid 1,80 mg/ml
injection Tobramycin sulfate 0,80 mg/ml
2353
Compatible
injection Linezolid 2 mg/ml
injection Tobramycin sulfate 5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Vancomycin hydrochloride 10 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Vasopressin 0.2 UI/ml
Sodium chloride 0,9% 2017
Compatible
injection Linezolid 2 mg/ml
injection Vecuronium bromide 1 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Verapamil hydrochloride 2.5 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Vincristine sulfate 0.05 mg/ml
None 1925
Compatible
injection Linezolid 2 mg/ml
injection Zidovudine 4 mg/ml
None 1925

  Mentions Légales