Last update :
19/11/2024
Anxiolytic   Diazepam  
injection
Oral solution suppository
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Ansiolin Italy
Bamyl Chile
Compaz Brazil
Daiv Argentina, Colombia
Diactal Argentina
Diapam Finland, Turkey
Diazem Turkey
Diazemuls Canada, Great Britain, Italy, Netherlands
Diazep Germany
Diazepam Australia, Canada, Colombia, Ecuador, Germany
Faustan Germany
Gewalcalm Austria
Kiatrium Brazil
Noan Italy
Normabel Croatia
Ortopsique Ecuador
Pacitran Peru
Pax Republic of South Africa
Relanium Poland
Rupediz Argentina
Stedon Greece
Stesolid Denmark, Germany, Iceland, Norway, Saudi Arabia, Sweden, Switzerland
Sunzepan Mexico
Tranject Republic of South Africa
Valium Austria, Belgium, Brazil, Colombia, Ecuador, Egypt, France, Germany, Italy, Luxembourg, Mexico, Morocco, Netherlands, Portugal, Republic of South Africa, Saudi Arabia, Spain, Switzerland, United Arab Emirates, Venezuela
Compatibility   injection   Compatibility : Diazepam              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Atracurium besylate 0.5 mg/ml
Glucose 5% 402
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Caffeine 10 mg/ml
None 3964
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Compatible
injection Diazepam 0.25 mg/ml
injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Immediate turbidity Incompatible
injection Diazepam 5 mg/ml
injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 1041
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Diazepam 0.5 mg/ml
injection Fentanyl citrate 25 µg/ml
Glucose 5% 1974
Production of gas bubbles Incompatible
injection Diazepam 5 mg/ml
injection Foscarnet sodium 24 mg/ml
None 73
Immediate precipitation Incompatible
injection Diazepam 1 mg/ml
injection Furosemide 1 mg/ml
Glucose 5% 1232
Compatible
injection Diazepam 0.5 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 1974
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Hydromorphone hydrochloride 2 >> 40 mg/ml
Glucose 5% 226
Loss of turbidity Incompatible
injection Diazepam 5 mg/ml
injection Ketorolac tromethamine 30 mg/ml
None 476
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Immediate turbidity Incompatible
injection Diazepam 5 mg/ml
injection Linezolid 2 mg/ml
None 1925
Immediate precipitation Incompatible
injection Diazepam >0,25 mg/ml
Glucose 5% 731
Compatible
injection Diazepam 0.5 mg/ml
injection Methadone hydrochloride 1 mg/ml
Glucose 5% 1974
Compatible
injection Diazepam 0.5 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Pancuronium bromide 0.05 mg/ml
Glucose 5% 402
Immediate precipitation Incompatible
injection Diazepam >0,25 mg/ml
Ringer’s lactate solution 731
Compatible
injection Diazepam 5 mg/ml
Parenteral nutrition (binary mixture) 939
Compatible
injection Diazepam 5 mg/ml
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Diazepam 5 mg/ml
injection Nafcillin sodium 33 mg/ml
Sodium chloride 0,9% 1366
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Subvisual incompatibility Incompatible
injection Diazepam 5 mg/ml
injection Paracetamol 10 mg/ml
None 3571
Precipitation after 1 hour Incompatible
injection Diazepam 5 mg/ml
injection Paracetamol 10 mg/ml
Glucose 5% 4435
Immediate instability of the emulsion Incompatible
injection Diazepam 5 mg/ml
injection Propofol 10 mg/ml
None 300
Compatible
injection Diazepam 10 mg/ml
injection Ranitidine hydrochloride 25 mg/ml
None 58
Immediate turbidity Incompatible
injection Diazepam 5 mg/ml
injection Salbutamol sulfate 1 mg/ml
None 3216
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Vecuronium bromide 0.1 mg/ml
Glucose 5% 402
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
Ringer’s lactate solution 4603
Immediate turbidity Incompatible
injection Diazepam 5 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 730
Immediate instability of the emulsion Incompatible
injection Diazepam 5 mg/ml
injection Propofol
660
Compatible
injection Diazepam 0.25 mg/ml
injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Precipitation after 15 minutes Incompatible
injection Diazepam 5 mg/ml
injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Immediate precipitation Incompatible
injection Diazepam >0,25 mg/ml
Sodium chloride 0,9% 731
Compatible
injection Diazepam 5 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Immediate precipitation Incompatible
injection Diazepam
injection Bivalirudin
3539
Unspecified incompatibility Incompatible
injection Diazepam
injection Bleomycin sulfate
4154
Compatible
injection Diazepam 5 mg/ml
injection Cefmetazole sodium 100 mg/ml
Water for Injection 93
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Unspecified incompatibility Incompatible
injection Diazepam
injection Ceftobiprole medocaril sodium
4650
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
injection Diazepam 5 mg/ml
injection Cimetidine hydrochloride 150 mg/ml
1438
Subvisual incompatibility Incompatible
injection Diazepam 5 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Immediate turbidity Incompatible
injection Diazepam
injection Dimenhydrinate
2087
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Immediate precipitation Incompatible
injection Diazepam
injection Esketamine
4700
Unspecified incompatibility Incompatible
injection Diazepam
injection Esmolol hydrochloride
3607
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Unspecified incompatibility Incompatible
injection Diazepam
injection Fluorouracil
3474
Unspecified incompatibility Incompatible
injection Diazepam
injection Glycopyrronium bromide
3599
Unspecified incompatibility Incompatible
injection Diazepam
injection Heparin sodium
3540
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Hetastarch 60 mg/ml
specific solvent 1721
Unspecified incompatibility Incompatible
injection Diazepam
injection Hyaluronidase
3184
Unspecified incompatibility Incompatible
injection Diazepam
injection Hyaluronidase
3617
Immediate precipitation Incompatible
injection Diazepam
injection Hydroxocobalamin
3932
Immediate precipitation Incompatible
injection Diazepam
injection Ketamine hydrochloride
3501
Unspecified incompatibility Incompatible
injection Diazepam
injection Linezolid
3560
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Meropenem 1 & 50 mg/ml
Sodium chloride 0,9% 266
Unspecified incompatibility Incompatible
injection Diazepam
injection Nalbuphine hydrochloride
3672
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Nalbuphine hydrochloride 2,5 >> 10 mg/ml
616
Compatible
injection Diazepam 0.04 mg/ml
injection Netilmicin sulfate 3 mg/ml
NaCl 0,9% or Glucose 5% 1200
Immediate precipitation Incompatible
injection Diazepam
injection Nicardipine hydrochloride
3941
Immediate precipitation Incompatible
injection Diazepam
injection Nicardipine hydrochloride
3614
Immediate precipitation Incompatible
injection Diazepam
injection Pantoprazole sodium
2090
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Paracetamol 10 mg/ml
4742
Immediate turbidity Incompatible
injection Diazepam 5 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 730
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Unspecified incompatibility Incompatible
injection Diazepam
injection Rocuronium bromide
3564
Unspecified incompatibility Incompatible
injection Diazepam
injection Tigecycline
3332
Unspecified incompatibility Incompatible
injection Diazepam
injection Tirofiban
1512
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Tirofiban 50 µg/ml
NaCl 0,9% or Glucose 5% 1603
Immediate precipitation Incompatible
injection Diazepam
injection Tramadol hydrochloride
3521
Immediate precipitation Incompatible
injection Diazepam 5 mg/ml
injection Valproic acid 2 & 20 mg/ml
NaCl 0,9% or Glucose 5% 4428
Compatible
injection Diazepam 0.02 mg/ml
injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057

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