Last update :
18/03/2025
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Analgesic   Tramadol hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Acugesic Malaysia
Adolonta Spain
Amadol Egypt
Analgon Peru
Contramal Belgium, France, Hungary, Italy, Turkey
Eufindol Chile
Fortradol Italy
Lafedol Argentina
Liochta Mexico
Mabron Malaysia, Romania, Spain
Megadol Chile, Colombia
Nobligan Denmark
Paxilfar Portugal
Poltram Poland
Prontalgin Italy
Sylador Saudi Arabia
Tadol Slovenia
Topalgic France
Trabilin Malaysia, Saudi Arabia
Tradolan Austria, Denmark, Iceland, Sweden
Tradonal Belgium, Luxembourg
Tramabene Austria
Tramadolor Austria, Croatia, Germany
Tramagetic Germany, Netherlands
Tramal Argentina, Brazil, Colombia, Ecuador, Egypt, Finland, Germany, Iran, Luxembourg, Netherlands, New Zealand, Peru, Poland, Portugal, Saudi Arabia, Slovenia, Switzerland, Tunisia, United Arab Emirates, Venezuela
Tramastad Austria
Zamadol Great Britain, India
Zydol Great Britain
Stability in solutions   injection   Stability in solutions : Tramadol hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Sodium chloride 0,9% 0,89 mg/ml 20-24°C Light
24 Hour
3075

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 4 mg/ml 2-8°C Protect from light
14 Day
1690
Level of evidence B+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 4 mg/ml 25°C With or without light
7 Day
1690
Level of evidence B+
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 & 4 mg/ml 40°C Protect from light
7 Day
1690
Level of evidence B+
Polyvinyl chloride Glucose 5% 1 mg/ml -20°C Protect from light
120 Day
1892
Level of evidence C
Polyvinyl chloride Glucose 5% 1 mg/ml 4°C Not specified
60 Day
1892
Level of evidence C
  Mentions Légales