Last update :
19/11/2024
Anti-arrhythmic   Verapamil hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Calaptin India
Calovera India
Cordilox Great Britain
Dilacoran Mexico
Filacard Germany
Flamon Switzerland
Geangin Denmark
Isocor Romania
Isoptin Australia, Austria, Egypt, Germany, Greece, Italy, Netherlands, New Zealand, Poland, Portugal, Saudi Arabia, Sweden, Switzerland, United States of America
Isoptina Chile
Isoptine Belgium, France, Luxembourg
Izoptomil Egypt
Lekoptin Iran
Manidon Spain
Palyuan Mexico
Securon Great Britain
Serriten Mexico
Unimylo Mexico
Vasolan Japan
Verahexal Germany
Veraloc Denmark
Veramex Germany
Verapabene Austria
Verapam Switzerland
Verapamil Canada, Germany, Hungary, Sweden, United States of America
Verapamilo Argentina, Chile, Colombia, Ecuador, Peru
Verpamil Finland, Malaysia
Compatibility   injection   Compatibility : Verapamil hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Amikacin sulfate 2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride 0,1 & 0,4 mg/ml
injection Aminophylline 1 mg/ml
Glucose 5% 364
Immediate precipitation Incompatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Aminophylline 1 mg/ml
NaCl 0,9% or Glucose 5% 706
Compatible
injection Verapamil hydrochloride 0.05 mg/ml
injection Amiodarone hydrochloride 1.8 mg/ml
NaCl 0,9% or Glucose 5% 242
Immediate turbidity Incompatible
injection Verapamil hydrochloride 10 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Immediate precipitation Incompatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Amphotericin B 0.1 mg/ml
Sodium chloride 0,9% 1057
Precipitation after 8 hours Incompatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Amphotericin B 0.1 mg/ml
Glucose 5% 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride 2,5 mg/ml
injection Amphotericin B cholesteryl sulfate complex 0,83 mg/ml
Glucose 5% 921
Immediate precipitation Incompatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Ampicillin sodium 40 mg/ml
NaCl 0,9% or Glucose 5% 371
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Ampicillin sodium 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 2,5 mg/ml
injection Argatroban 1 mg/ml
Sodium chloride 0,9% 1964
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Ascorbic acid 1 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Atropine sulfate 0.0008 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 1.25 mg/ml
injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
injection Verapamil hydrochloride 2,5 mg/ml
injection Bivalirudin 5 mg/ml
NaCl 0,9% or Glucose 5% 1944
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Bretylium tosilate 2 mg/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Calcium chloride 2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Calcium gluconate 2 mg/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Cefamandole nafate 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Cefazolin sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Cefotaxime sodium 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Cefoxitin sodium 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Chloramphenicol sodium succinate 2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Ciprofloxacin lactate 2 mg/ml
NaCl 0,9% or Glucose 5% 288
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Clindamycin phosphate 1.2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 1 mg/ml
injection Clonidine hydrochloride 0.009 & 0.03 mg/ml
4130
Compatible
injection Verapamil hydrochloride 2,5 mg/ml
injection Clonidine hydrochloride 0,018 mg/ml
Sodium chloride 0,9% 2018
Immediate precipitation Incompatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Co-trimoxazole 0.16/0.8 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Dexamethasone sodium phosphate 0.04 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 1.25 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Diazepam 0.02 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Digoxin 2 µg/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride
injection Dimenhydrinate
2087
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 1041
Compatible
injection Verapamil hydrochloride 0.16 mg/ml
injection Dobutamine hydrochloride 0.25 mg/ml
NaCl 0,9% or Glucose 5% 1045
Color change after 24 hours Incompatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Dobutamine hydrochloride 0.5 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Dopamine hydrochloride 0.4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Epinephrine hydrochloride 2 µg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride
injection Eptifibatide
3934
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Erythromycin lactobionate 2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.1 mg/ml
injection Famotidine 0.2 mg/ml
Glucose 5% 398
Compatible
injection Verapamil hydrochloride 1.25 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Immediate precipitation Incompatible
injection Verapamil hydrochloride 0.5 mg/ml
injection Furosemide 1 mg/ml
Sodium chloride 0,9% 1232
Compatible
injection Verapamil hydrochloride 1.25 mg/ml
injection Hetastarch 60 mg/ml
specific solvent 1721
Turbidity in 8 hours Incompatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Human albumin 25 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
NaHCO3 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride
NaHCO3 1100
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Furosemide 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Gentamicin sulfate 0.16 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Heparin sodium 20 UI/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 2,5 mg/ml
Ringer’s lactate solution 4603
Color change Incompatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Hydralazine hydrochloride 0.04 mg/ml
Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Hydrocortisone sodium succinate 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Hydromorphone hydrochloride 0.016 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Insulin 0,2 UI/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride 1,25 mg/ml
injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Isoprenaline hydrochloride 0.01 mg/ml
NaCl 0,9% or Glucose 5% 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Lidocaine hydrochloride 2 mg/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Magnesium sulfate 10 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Mannitol 0.025 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Metaraminol 0.02 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Methylprednisolone sodium succinate 0.25 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Metoclopramide hydrochloride 0.02 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 1 & 1.25 mg/ml
injection Milrinone lactate 0.100 & 0.350 mg/ml
Glucose 5% 191
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Morphine sulfate 0.03 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Moxalactam 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Nafcillin sodium 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Nafcillin sodium 40 mg/ml
NaCl 0,9% or Glucose 5% 371
Immediate precipitation Incompatible
injection Verapamil hydrochloride
injection Nafcillin sodium
Glucose 5% 1099
Immediate precipitation Incompatible
injection Verapamil hydrochloride
injection Nafcillin sodium
1351
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Naloxone hydrochloride 0.0008 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Nitroglycerin 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Nitroprusside sodium 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Norepinephrine bitartrate 0.008 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Oxacillin sodium 4 mg/ml
NaCl 0,9% or Glucose 5% 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Oxacillin sodium 40 mg/ml
NaCl 0,9% or Glucose 5% 371
Compatible
injection Verapamil hydrochloride 1,25 mg/ml
injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Oxytocin 0.04 UI/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Pancuronium bromide 0.008 mg/ml
NaCl 0,9% or Glucose 5% 1057
Immediate precipitation Incompatible
injection Verapamil hydrochloride
injection Pantoprazole sodium
2090
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Paracetamol 10 mg/ml
4742
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Penicillin G potassium 0.1 MUI/ml
NaCl 0,9% or Glucose 5% 371
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Penicillin G potassium 0.01 MUI/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Penicillin G sodium 0.01 MUI/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Pentobarbital sodium 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 62
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Pethidine hydrochloride 0.15 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Phenobarbital sodium 0.26 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Phentolamine mesylate 0.01 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Phenytoin sodium 0,5 mg/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Piperacillin sodium 40 mg/ml
NaCl 0,9% or Glucose 5% 371
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Potassium chloride 80 mEq/l
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Potassium phosphate 0.088 mmol/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Procainamide hydrochloride 2 mg/ml
Sodium chloride 0,9% 706
Compatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Propofol 10 mg/ml
None 300
Instability of the emulsion after 4 hours Incompatible
injection Verapamil hydrochloride 2.5 mg/ml
injection Propofol
660
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Propranolol hydrochloride 0.004 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Protamine hydrochloride 0.1 UI/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0,08 mg/ml
injection Quinidine gluconate 0,8 mg/ml
Sodium chloride 0,9% 706
Immediate precipitation Incompatible
injection Verapamil hydrochloride
injection Sodium bicarbonate
Sodium chloride 0,45% 1100
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Sodium bicarbonate 7.49 mg/ml
NaCl 0,9% or Glucose 5% 1057
Unspecified incompatibility Incompatible
injection Verapamil hydrochloride
injection Sugammadex
2328
Compatible
injection Verapamil hydrochloride 0.1 & 0.4 mg/ml
injection Theophylline 0.4 & 4 mg/ml
Glucose 5% 372
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Tobramycin sulfate 0.16 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Vancomycin hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Verapamil hydrochloride 0.08 mg/ml
injection Vasopressin 0.04 UI/ml
NaCl 0,9% or Glucose 5% 1057

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