Last update :
28/04/2024
References   References 479  
Type : Journal

Research teams : Iowa City - University of Iowa, College of Pharmacy
Authors : Min DI, Brown T, HWang GC.
Title : Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 49: 2964-2966. 1992

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAciclovir sodium Antiviral
Compatible 10 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionAminophylline Various
Compatible 2 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionAmphotericin B Antifungal
Compatible 5 mg/ml + InjectionTacrolimus 1000 µg/ml + Water for Injection
InjectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 50 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCefazolin sodium Antibiotic
Compatible 40 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCeftazidime Antibiotic
Compatible 20 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCeftriaxone disodium Antibiotic
Compatible 40 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionChloramphenicol sodium succinate Antibiotic
Compatible 20 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 150 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCiprofloxacin lactate Antibiotic
Compatible 1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionClindamycin phosphate Antibiotic
Compatible 12 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionCo-trimoxazole Antibiotic
Compatible 16/8 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionDigoxin Cardiotonic
Compatible 250 µg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionDopamine hydrochloride Cardiotonic
Compatible 1,6 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionDoxycycline hyclate Antibiotic
Compatible 5 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionErythromycin lactobionate Antibiotic
Compatible 20 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionFolinate calcium Cytoprotective
Compatible 10 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Compatible 10 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionGanciclovir sodium Antiviral
Compatible 50 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionGentamicin sulfate Antibiotic
Compatible 4 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionHaloperidol lactate Neuroleptic
Compatible 2,5 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionHeparin sodium Anticoagulant
Compatible 10 UI/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 50 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionImipenem - cilastatin sodium Antibiotic
Compatible 10 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionInsulin Glucose-lowering
Compatible 0,1 UI/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0,04 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionLorazepam Anxiolytic
Compatible 1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 0,8 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 0,2 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionNitroglycerin Vasodilator
Compatible 0,1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionNitroprusside sodium Vasodilator
Compatible 0,004 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionOxacillin sodium Antibiotic
Compatible 40 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionPenicillin G potassium Antibiotic
Compatible 0,1 MUI/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionPhenytoin sodium Antiepileptic
Incompatible 5 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionPiperacillin sodium Antibiotic
Compatible 80 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionPotassium chloride Electrolyte
Compatible 2000 mEq/l + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionPropranolol hydrochloride Beta-blocker
Compatible 1 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionTacrolimus Immunosuppressant
Compatible 1000 µg/ml + InjectionAciclovir sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionAminophylline 2 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionAmphotericin B 5 mg/ml + Water for Injection
Compatible 1000 µg/ml + InjectionAmpicillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionAmpicillin sodium - sulbactam sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionBenztropine mesylate 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCalcium gluconate 100 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCefazolin sodium 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCeftazidime 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCeftriaxone disodium 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCefuroxime sodium 30 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionChloramphenicol sodium succinate 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCimetidine hydrochloride 150 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCiprofloxacin lactate 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionClindamycin phosphate 12 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionCo-trimoxazole 16/8 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionDexamethasone sodium phosphate 4 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionDigoxin 250 µg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionDiphenhydramine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionDobutamine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionDopamine hydrochloride 1,6 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionDoxycycline hyclate 5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionErythromycin lactobionate 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionFolinate calcium 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionGanciclovir sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionGentamicin sulfate 4 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionHaloperidol lactate 2,5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionHeparin sodium 10 UI/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionHydrocortisone sodium succinate 50 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionImipenem - cilastatin sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionInsulin 0,1 UI/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionIsoprenaline hydrochloride 0,04 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionLorazepam 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionMethylprednisolone sodium succinate 0,8 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionMetoclopramide hydrochloride 0,2 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionMetronidazole 5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionNitroglycerin 0,1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionNitroprusside sodium 0,004 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionOxacillin sodium 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionPenicillin G potassium 0,1 MUI/ml + Sodium chloride 0,9%
Incompatible 1000 µg/ml + InjectionPhenytoin sodium 5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionPiperacillin sodium 80 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionPotassium chloride 2000 mEq/l + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionPropranolol hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionRanitidine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionTobramycin sulfate 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + InjectionVancomycin hydrochloride 5 mg/ml + Sodium chloride 0,9%
InjectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
InjectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + InjectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%

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