Last update :
29/10/2024
InfoStab
Infostab
List of drugs
List of drugs
Summary lists
Summary lists
Search for compatibilities
Search for compatibilities
Y-site compatibility table
Y-site compatibility table
References
References
Research teams
Research teams
valistab
valistab
Poster
Poster
Links
Links
Sponsors
Sponsors
Authors
Authors
User’s guide
User’s guide
Newsletter
Newsletter
References   References 4493  
Type : Journal
Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : Le Guyader G, Vieillard V, Paul M.
Title : Physicochemical stability study of MYL-1401O, a biosimilar of trastuzumab, following a transient temperature excursion.
Reference : J Oncol Pharm Practice 2020
Level of Evidence : 
Level of evidence A+
Physical stability : 
Turbidimetry Protein: Size Exclusion Chromatography Protein: Dynamic Light Scattering 
Chemical stability : 
Protein: ionic chromatography
Protein: ultraviolet spectrometry and second derivative
Protein: intrared spectrometry and second derivative
ultraviolet spectrometry
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionTrastuzumab Anticancer drug
Stability in solutions Glass Water for Injection 21 mg/ml 4°C Protect from light
30 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 0.8 & 2.4 mg/ml 25°C Not specified
3 Day
Biosimilar
Stability in solutions Polyolefine Sodium chloride 0,9% 0.8 & 2.4 mg/ml 4°C Not specified
90 Day
Biosimilar
  Mentions Légales