Last update :
19/11/2024
References   References 479  
Type : Journal

Research teams : Iowa City - University of Iowa, College of Pharmacy
Authors : Min DI, Brown T, HWang GC.
Title : Visual compatibility of tacrolimus with commonly used drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 49: 2964-2966. 1992

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAciclovir sodium Antiviral
Compatible 10 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionAminophylline Various
Compatible 2 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionAmphotericin B Antifungal
Compatible 5 mg/ml + injectionTacrolimus 1000 µg/ml + Water for Injection
injectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 50 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCefazolin sodium Antibiotic
Compatible 40 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCeftazidime Antibiotic
Compatible 20 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCeftriaxone disodium Antibiotic
Compatible 40 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionChloramphenicol sodium succinate Antibiotic
Compatible 20 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 150 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCiprofloxacin lactate Antibiotic
Compatible 1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionClindamycin phosphate Antibiotic
Compatible 12 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionCo-trimoxazole Antibiotic
Compatible 16/8 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionDopamine hydrochloride Cardiotonic
Compatible 1,6 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionDoxycycline hyclate Antibiotic
Compatible 5 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionErythromycin lactobionate Antibiotic
Compatible 20 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionFolinate calcium Cytoprotective
Compatible 10 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Compatible 10 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionGanciclovir sodium Antiviral
Compatible 50 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionGentamicin sulfate Antibiotic
Compatible 4 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionHaloperidol lactate Neuroleptic
Compatible 2,5 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Compatible 10 UI/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 50 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionImipenem - cilastatin sodium Antibiotic
Compatible 10 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionInsulin Glucose-lowering
Compatible 0,1 UI/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0,04 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionLorazepam Anxiolytic
Compatible 1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 0,8 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 0,2 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionNitroglycerin Vasodilator
Compatible 0,1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionNitroprusside sodium Vasodilator
Compatible 0,004 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionOxacillin sodium Antibiotic
Compatible 40 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionPenicillin G potassium Antibiotic
Compatible 0,1 MUI/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionPhenytoin sodium Antiepileptic
Incompatible 5 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionPiperacillin sodium Antibiotic
Compatible 80 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionPotassium chloride Electrolyte
Compatible 2000 mEq/l + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionPropranolol hydrochloride Beta-blocker
Compatible 1 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionTacrolimus Immunosuppressant
Compatible 1000 µg/ml + injectionAciclovir sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionAminophylline 2 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionAmphotericin B 5 mg/ml + Water for Injection
Compatible 1000 µg/ml + injectionAmpicillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionAmpicillin sodium - sulbactam sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionBenztropine mesylate 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCalcium gluconate 100 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCefazolin sodium 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCeftazidime 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCeftriaxone disodium 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCefuroxime sodium 30 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionChloramphenicol sodium succinate 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCimetidine hydrochloride 150 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCiprofloxacin lactate 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionClindamycin phosphate 12 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionCo-trimoxazole 16/8 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionDexamethasone sodium phosphate 4 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionDigoxin 250 µg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionDiphenhydramine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionDobutamine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionDopamine hydrochloride 1,6 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionDoxycycline hyclate 5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionErythromycin lactobionate 20 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionFolinate calcium 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionGanciclovir sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionGentamicin sulfate 4 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionHaloperidol lactate 2,5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionHeparin sodium 10 UI/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionHydrocortisone sodium succinate 50 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionImipenem - cilastatin sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionInsulin 0,1 UI/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionIsoprenaline hydrochloride 0,04 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionLorazepam 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionMethylprednisolone sodium succinate 0,8 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionMetoclopramide hydrochloride 0,2 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionMetronidazole 5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionNitroglycerin 0,1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionNitroprusside sodium 0,004 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionOxacillin sodium 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionPenicillin G potassium 0,1 MUI/ml + Sodium chloride 0,9%
Incompatible 1000 µg/ml + injectionPhenytoin sodium 5 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionPiperacillin sodium 80 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionPotassium chloride 2000 mEq/l + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionPropranolol hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionRanitidine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionTobramycin sulfate 40 mg/ml + Sodium chloride 0,9%
Compatible 1000 µg/ml + injectionVancomycin hydrochloride 5 mg/ml + Sodium chloride 0,9%
injectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%
injectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + injectionTacrolimus 1000 µg/ml + Sodium chloride 0,9%

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