Last update :
19/11/2024
References   References 1611  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/58/6/504

Research teams : Cleveland - Cleveland Clinic Fundation
Authors : Chalmers JR, Bobek MB, Militello MA.
Title : Visual compatibility of amiodarone hydrochloride injection with various intravenous drugs.
Reference : Am J Health-Syst Pharm ; 58: 504-506. 2001

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmiodarone hydrochloride Anti-arrhythmic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Compatible 6 mg/ml + injectionAmphotericin B 0,5 mg/ml + Glucose 5%
Incompatible 6 mg/ml + NaHCO3
Incompatible 6 mg/ml + injectionAmpicillin sodium - sulbactam sodium 30 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 6 mg/ml + injectionAtracurium besylate 5 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionAtropine sulfate 0,4 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionCalcium gluconate 10 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionCeftazidime 40 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionCeftizoxime sodium 40 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionCeftriaxone disodium 20 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionDigoxin 250 µg/ml + Glucose 5%
Compatible 6 mg/ml + injectionEpinephrine hydrochloride 1000 µg/ml + Glucose 5%
Compatible 6 mg/ml + injectionEptifibatide 2 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionEptifibatide 0,75 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionFamotidine 10 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionFentanyl citrate 50 µg/ml + Glucose 5%
Compatible 6 mg/ml + injectionFluconazole 2 mg/ml + NaCl 0,45% Glucose 2,5%
Incompatible 6 mg/ml + injectionFurosemide 10 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionGemcitabine hydrochloride 5 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionImipenem - cilastatin sodium 5 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionLorazepam 1 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionMagnesium sulfate 500 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionMethylprednisolone sodium succinate 125 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionMilrinone lactate 0,4 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionMorphine sulfate 10 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionNitroprusside sodium 0,4 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionPiperacillin sodium 60 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionPiperacillin sodium / tazobactam 60 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionPotassium phosphate 0.12 mmol/ml + Glucose 5%
Incompatible 6 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Incompatible 6 mg/ml + injectionSodium Phosphate 0,12 mmol/ml + Glucose 5%
Compatible 6 mg/ml + injectionTirofiban 250 µg/ml + Glucose 5%
Compatible 6 mg/ml + injectionTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionVancomycin hydrochloride 4 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 6 mg/ml + injectionVasopressin 0.2 UI/ml + NaCl 0,45% Glucose 2,5%
Compatible 6 mg/ml + injectionVecuronium bromide 1 mg/ml + Glucose 5%
injectionAmphotericin B Antifungal
Compatible 0,5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Incompatible 30 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + NaCl 0,9% or Glucose 5%
injectionAtracurium besylate Curarimimetic
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionAtropine sulfate Antimuscarinic
Compatible 0,4 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionCalcium gluconate Electrolyte
Compatible 10 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Incompatible 40 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionCeftizoxime sodium Antibiotic
Compatible 40 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionDigoxin Cardiotonic
Incompatible 250 µg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionEptifibatide Anticoagulant
Compatible 2 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
Compatible 0,75 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 10 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + NaCl 0,45% Glucose 2,5%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionGemcitabine hydrochloride Anticancer drug
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionImipenem - cilastatin sodium Antibiotic
Incompatible 5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionLabetalol hydrochloride Beta-blocker
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionLorazepam Anxiolytic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionMagnesium sulfate Electrolyte
Incompatible 500 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 125 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionMilrinone lactate Cardiotonic
Compatible 0,4 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionNitroprusside sodium Vasodilator
Compatible 0,4 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionPiperacillin sodium Antibiotic
Incompatible 60 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 60 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionPotassium phosphate Electrolyte
Incompatible 0.12 mmol/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionSodium Phosphate Electrolyte
Incompatible 0,12 mmol/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionTirofiban Anticoagulant
Compatible 250 µg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 4 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%
injectionVasopressin Hormone
Compatible 0.2 UI/ml + injectionAmiodarone hydrochloride 6 mg/ml + NaCl 0,45% Glucose 2,5%
injectionVecuronium bromide Curarimimetic
Compatible 1 mg/ml + injectionAmiodarone hydrochloride 6 mg/ml + Glucose 5%

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