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Anticancer drug   Azacitidine  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Amilix Argentina
Arquimes Argentina
Azacimyl Chile
Azacitidina Argentina, Chile, Peru
Azacitidine United States of America
Azacor Peru
Azadin Turkey
Azamex Argentina
Azanova Argentina
Azateva Argentina
Azida Turkey
Azitech Argentina
Iclacitidina Peru
Iterbil Argentina
Maturus Argentina
Mietozitidina Argentina, Peru
Nimodac Argentina
Remitiva Argentina, Chile
Tazadir Argentina
Vidaza Argentina, Belgium, Canada, Chile, Colombia, France, Germany, Great Britain, Iceland, Malaysia, Mexico, New Zealand, Norway, Peru, Romania, Spain, Switzerland, Turkey, United States of America
Wunduza Chile
Zacidonel Mexico
Zylatadina Argentina
References   Injection   References : Azacitidine  
Type Publication
414 Journal Den Hartigh J, Brandenburg HCR, Vermeij P.
Stability of azacitidine in lactated Ringer’s injection frozen in polypropylene syringes.
Am J Hosp Pharm 1989 ; 46: 2500-2505.
1039 Journal Cheung YW, Vishnuvajjala BR, Morris NL, Flora KP.
Stability of azacitidine in infusion fluids.
Am J Hosp Pharm 1984 ; 41: 1156-1159.
3204 Journal Duriez A, Vigneron J.H, Zenier H.A, May I, Demoré B.M.
Stability of Azacitidine Suspensions.
Ann Pharmacotherapy 2011 ;45, 4:546.
3236 Manufacturer Azacitidine (Vidaza®) - Résumé des caractéristiques du produit
Celgene 2011
3246 Poster Vieillard V, Appudurai O, Voytenko S, Astier A, Paul M.
Stabilité physico-chimique de la suspension d'azacitidine (25 mg/mL) conservée à 4°C.
SFPO Congress Mandelieu, France 2011
3351 Journal Walker S.E, Charbonneau L.F, Law S, Earle C.
Stability of Azacitidine in Sterile Water for Injection.
Can J Hosp Pharm 2012 ; 65, 5: 352-359
3534 Journal Legeron R, Xuereb F, Djabarouti S, Saux M.C, Breilh D.
Chemical stability of azacitidine suspensions for injection after cold-chain reconstitution of powder and storage
Am J Health-Syst Pharm 2013 ; 70:2137-2142
3816 Poster Balouzet C, Chanat C, Jobard M, Brandely-Piat ML, Chast F.
Stabilité des poches d'azacitidine pour injection intraveineuse (1- 4 et 2,4 mg/mL) conservées à 4°C.
SFPO Congress, Nantes, France 2015
3818 Journal Balouzet C, Chanat C, Jobard M, Brandely-Piat M-L, Chast F.
Stability of 25 mg/mL 5-azacitidine suspension kept in fridge after freezing.
Pharmaceutical Technology in Hospital Pharmacy 2017 ;2, 1:11-16.
4227 Poster Tyono I, Law S, Charbonneau L.F, Walker S.E.
Stability of Azacitidine Solutions In Sterile Water for Injection.
Prof Practice Conference - Canadian Society of PH 2019
4628 Journal Iudicello A, Genovese F, Strusi V, Dominici M, Ruozi B.
Development and Validation of a New Storage Procedure to Extend the In-Use Stability of Azacitidine in Pharmaceutical Formulations.
Pharmaceuticals 2021 ; 14, 943.
4697 Journal Trambloy Q, Vigneron J, Clarot I, Blaise F, D’Huart E, Demoré B.
Physicochemical stability of azacitidine suspensions at 25 mg/mL in polypropylene syringes stored under different conditions of storage.
Pharmaceutical Technology in Hospital Pharmacy 2022 2022; 7(1): 20220003
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