Last update :
19/09/2022
References   References 4697  
Type : Journal
Web link : https://doi.org/10.1515/pthp-2022-0003

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Trambloy Q, Vigneron J, Clarot I, Blaise F, D’Huart E, Demoré B.
Title : Physicochemical stability of azacitidine suspensions at 25 mg/mL in polypropylene syringes stored under different conditions of storage.
Reference : Pharmaceutical Technology in Hospital Pharmacy 2022; 7(1): 20220003 2022

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionAzacitidine Anticancer drug
Stability in solutions Polypropylen Syringe Water for Injection (4°C) 25 mg/ml -20°C Protect from light
28 Day
Stability in solutions Polypropylen Syringe Water for Injection (4°C) 25 mg/ml 2-8°C Protect from light
4 Day
Conflicting data
Stability in solutions Polypropylen Syringe Water for Injection (4°C) 25 mg/ml 20-25°C Protect from light
2 Hour

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