Last update :
19/11/2024
References   References 496  
Type : Journal

Research teams : Los Angeles - USC/Norris Cancer Center
Authors : Lor E, Sheybani T, Takagi J.
Title : Visual compatibility of fluconazole with commonly used injectable drugs during simulated Y-site administration.
Reference : Am J Hosp Pharm ; 48: 744-746. 1991

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Compatible 10 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionAmikacin sulfate Antibiotic
Compatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionAminophylline Various
Compatible 25 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionAmphotericin B Antifungal
Incompatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionAmpicillin sodium Antibiotic
Incompatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 60 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionAztreonam Antibiotic
Compatible 40 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCalcium gluconate Electrolyte
Incompatible 100 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCefazolin sodium Antibiotic
Compatible 40 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCefotaxime sodium Antibiotic
Incompatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCefoxitin sodium Antibiotic
Compatible 40 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCeftazidime Antibiotic
Incompatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCeftriaxone disodium Antibiotic
Incompatible 40 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCefuroxime sodium Antibiotic
Incompatible 30 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionChloramphenicol sodium succinate Antibiotic
Incompatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 25 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 150 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionClindamycin phosphate Antibiotic
Incompatible 24 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionCo-trimoxazole Antibiotic
Incompatible 16 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionDigoxin Cardiotonic
Incompatible 250 µg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionDroperidol Neuroleptic
Compatible 2.5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionErythromycin lactobionate Antibiotic
Incompatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionFamotidine Antihistamine (H2)
Compatible 10 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionAciclovir sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionAmikacin sulfate 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionAminophylline 25 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionAmphotericin B 5 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionAmpicillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionAmpicillin sodium - sulbactam sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionAztreonam 40 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionBenztropine mesylate 1 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionCalcium gluconate 100 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionCefazolin sodium 40 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionCefotaxime sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionCefoxitin sodium 40 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionCeftazidime 20 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionCeftriaxone disodium 40 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionCefuroxime sodium 30 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionChloramphenicol sodium succinate 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionChlorpromazine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionCimetidine hydrochloride 150 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionClindamycin phosphate 24 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionCo-trimoxazole 16 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionDexamethasone sodium phosphate 4 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionDiazepam 5 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionDigoxin 250 µg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionDiphenhydramine hydrochloride 50 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionDroperidol 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionErythromycin lactobionate 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionFamotidine 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionFolinate calcium 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionFoscarnet sodium 24 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionGanciclovir sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionGentamicin sulfate 4 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionHaloperidol lactate 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionHeparin sodium 1000 UI/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionHydroxyzine dihydrochloride 50 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionImipenem - cilastatin sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionMetronidazole 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionMorphine sulfate 25 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionNafcillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionOxacillin sodium 40 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionPenicillin G potassium 0.1 MUI/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionPentamidine isetionate 6 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionPhenytoin sodium 50 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + injectionPiperacillin sodium 80 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionProchlorperazine edysilate 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionPromethazine hydrochloride 50 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionTicarcillin / clavulanic acid 60 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionTobramycin sulfate 40 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionVancomycin hydrochloride 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + injectionZidovudine 10 mg/ml + Sodium chloride 0,9%
injectionFolinate calcium Cytoprotective
Compatible 10 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionFoscarnet sodium Antiviral
Compatible 24 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionGanciclovir sodium Antiviral
Compatible 50 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionGentamicin sulfate Antibiotic
Compatible 4 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionHaloperidol lactate Neuroleptic
Incompatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Compatible 1000 UI/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionHydroxyzine dihydrochloride Anxiolytic
Incompatible 50 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionImipenem - cilastatin sodium Antibiotic
Incompatible 10 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionMorphine sulfate Analgesic
Compatible 25 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionNafcillin sodium Antibiotic
Compatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionOxacillin sodium Antibiotic
Compatible 40 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionPenicillin G potassium Antibiotic
Compatible 0.1 MUI/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionPentamidine isetionate Antibiotic
Incompatible 6 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionPhenytoin sodium Antiepileptic
Compatible 50 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionPiperacillin sodium Antibiotic
Incompatible 80 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionProchlorperazine edysilate Neuroleptic
Compatible 5 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionTicarcillin / clavulanic acid Antibiotic
Compatible 60 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionVancomycin hydrochloride Antibiotic
Compatible 20 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%
injectionZidovudine Antiviral
Compatible 10 mg/ml + injectionFluconazole 2 mg/ml + Sodium chloride 0,9%

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