Last update :
18/07/2024
References   References 2109  
Type : Journal
Web link : http://www.pharmactuel.com/index.php/pharmactuel/issue/view/48

Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Pelletier E, Forest JM, Hildgen P.
Title : Compatibilité de la kétamine injectable lors de l’administration en dérivé avec d’autres médicaments usuels.
Reference : Pharmactuel ; 39: 71-75. 2006

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionAmikacin sulfate Antibiotic
Compatible 250 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionAminophylline Various
Incompatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionAmpicillin sodium Antibiotic
Incompatible 250 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCaffeine Respiratory stimulant
Compatible 10 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCefazolin sodium Antibiotic
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCefotaxime sodium Antibiotic
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCeftazidime Antibiotic
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCefuroxime sodium Antibiotic
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 25 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCiclosporin Immunosuppressant
Incompatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionClindamycin phosphate Antibiotic
Compatible 150 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCloxacillin sodium Antibiotic
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionCo-trimoxazole Antibiotic
Incompatible 80/16 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 10 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDigoxin Cardiotonic
Compatible 50 µg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDimenhydrinate Antihistamine (H1)
Compatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDobutamine hydrochloride Cardiotonic
Compatible 12.5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionDopamine hydrochloride Cardiotonic
Compatible 40 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionGentamicin sulfate Antibiotic
Compatible 40 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionHeparin sodium Anticoagulant
Incompatible 25000 UI/ml + injectionKetamine hydrochloride 50 mg/ml
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 125 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionInsulin Glucose-lowering
Incompatible 100 UI/ml + injectionKetamine hydrochloride 50 mg/ml
injectionKetamine hydrochloride General anesthetic
Incompatible 50 mg/ml + NaHCO3
Incompatible 50 mg/ml + injectionAciclovir sodium 50 mg/ml
Compatible 50 mg/ml + injectionAmikacin sulfate 250 mg/ml
Incompatible 50 mg/ml + injectionAminophylline 50 mg/ml
Compatible 50 mg/ml + injectionAmiodarone hydrochloride 50 mg/ml
Incompatible 50 mg/ml + injectionAmpicillin sodium 250 mg/ml
Compatible 50 mg/ml + injectionAtropine sulfate 0.4 mg/ml
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml
Compatible 50 mg/ml + injectionCalcium gluconate 100 mg/ml
Compatible 50 mg/ml + injectionCefazolin sodium 100 mg/ml
Compatible 50 mg/ml + injectionCefotaxime sodium 100 mg/ml
Compatible 50 mg/ml + injectionCeftazidime 100 mg/ml
Compatible 50 mg/ml + injectionCefuroxime sodium 100 mg/ml
Compatible 50 mg/ml + injectionChlorpromazine hydrochloride 25 mg/ml
Incompatible 50 mg/ml + injectionCiclosporin 50 mg/ml
Compatible 50 mg/ml + injectionClindamycin phosphate 150 mg/ml
Compatible 50 mg/ml + injectionCloxacillin sodium 100 mg/ml
Incompatible 50 mg/ml + injectionCo-trimoxazole 80/16 mg/ml
Incompatible 50 mg/ml + injectionDexamethasone sodium phosphate 10 mg/ml
Compatible 50 mg/ml + injectionDigoxin 50 µg/ml
Compatible 50 mg/ml + injectionDimenhydrinate 50 mg/ml
Compatible 50 mg/ml + injectionDiphenhydramine hydrochloride 50 mg/ml
Compatible 50 mg/ml + injectionDobutamine hydrochloride 12.5 mg/ml
Compatible 50 mg/ml + injectionDopamine hydrochloride 40 mg/ml
Compatible 50 mg/ml + injectionEpinephrine hydrochloride 1000 µg/ml
Incompatible 50 mg/ml + injectionFurosemide 10 mg/ml
Compatible 50 mg/ml + injectionGentamicin sulfate 40 mg/ml
Incompatible 50 mg/ml + injectionHeparin sodium 25000 UI/ml
Compatible 50 mg/ml + injectionHydrocortisone sodium succinate 125 mg/ml
Incompatible 50 mg/ml + injectionInsulin 100 UI/ml
Incompatible 50 mg/ml + injectionLorazepam 4 mg/ml
Compatible 50 mg/ml + injectionMagnesium sulfate 500 mg/ml
Incompatible 50 mg/ml + injectionMeropenem 50 mg/ml
Compatible 50 mg/ml + injectionMethylprednisolone acetate 62.5 mg/ml
Compatible 50 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml
Compatible 50 mg/ml + injectionMetronidazole 5 mg/ml
Compatible 50 mg/ml + injectionMidazolam hydrochloride 5 mg/ml
Compatible 50 mg/ml + injectionMilrinone lactate 1 mg/ml
Compatible 50 mg/ml + injectionNaloxone hydrochloride 0.4 mg/ml
Incompatible 50 mg/ml + injectionNitroglycerin 5 mg/ml
Compatible 50 mg/ml + injectionOxytocin 10 UI/ml
Compatible 50 mg/ml + injectionPancuronium bromide 2 mg/ml
Compatible 50 mg/ml + injectionPethidine hydrochloride 100 mg/ml
Incompatible 50 mg/ml + injectionPhenytoin sodium 50 mg/ml
Incompatible 50 mg/ml + injectionPiperacillin sodium 200 mg/ml
Compatible 50 mg/ml + injectionPiperacillin sodium / tazobactam 200 mg/ml
Compatible 50 mg/ml + injectionPotassium chloride 2000 mEq/l
Incompatible 50 mg/ml + injectionPotassium phosphate 4 mmol/ml
Compatible 50 mg/ml + injectionPromethazine hydrochloride 25 mg/ml
Compatible 50 mg/ml + injectionRanitidine hydrochloride 25 mg/ml
Incompatible 50 mg/ml + injectionSalbutamol sulfate 1 mg/ml
Incompatible 50 mg/ml + injectionSodium bicarbonate 84 mg/ml
Compatible 50 mg/ml + injectionTobramycin sulfate 40 mg/ml
Compatible 50 mg/ml + injectionVancomycin hydrochloride 50 mg/ml
injectionLorazepam Anxiolytic
Incompatible 4 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMagnesium sulfate Electrolyte
Compatible 500 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMeropenem Antibiotic
Incompatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMethylprednisolone acetate Anti-inflammatory
Compatible 62.5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionMilrinone lactate Cardiotonic
Compatible 1 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionNaloxone hydrochloride Antidote
Compatible 0.4 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionOxytocin Various
Compatible 10 UI/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPancuronium bromide Curarimimetic
Compatible 2 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPethidine hydrochloride Analgesic
Compatible 100 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPiperacillin sodium Antibiotic
Incompatible 200 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 200 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPotassium chloride Electrolyte
Compatible 2000 mEq/l + injectionKetamine hydrochloride 50 mg/ml
injectionPotassium phosphate Electrolyte
Incompatible 4 mmol/ml + injectionKetamine hydrochloride 50 mg/ml
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 25 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionSalbutamol sulfate Beta-stimulant
Incompatible 1 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + injectionKetamine hydrochloride 50 mg/ml
injectionVancomycin hydrochloride Antibiotic
Compatible 50 mg/ml + injectionKetamine hydrochloride 50 mg/ml

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