Last update :
08/11/2024
References   References 1072  
Type : Journal

Research teams : Albany - Albany Medical Hospital Center
Authors : Saltsmann CL, Tom CM, Mitchell A, Fan JH, Gailey RA.
Title : Compatibility of levofloxacin with 34 medications during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 56: 1458-1459. 1999

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 50 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionAlprostadil Vasodilator
Incompatible 500 µg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionAmikacin sulfate Antibiotic
Compatible 50 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionAminophylline Various
Compatible 25 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionAmpicillin sodium Antibiotic
Compatible 50 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionCaffeine Respiratory stimulant
Compatible 5 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionCefotaxime sodium Antibiotic
Compatible 200 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 150 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionClindamycin phosphate Antibiotic
Compatible 150 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 12,5 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 80 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 10 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 10 UI/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionIndomethacin sodium trihydrate Anti-inflammatory
Incompatible 1 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionInsulin Glucose-lowering
Incompatible 100 UI/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
Incompatible 1 UI/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0,2 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionLevofloxacine Antibiotic
Incompatible 5 mg/ml + injectionAciclovir sodium 50 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionAlprostadil 500 µg/ml + Glucose 5%
Compatible 5 mg/ml + injectionAmikacin sulfate 50 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionAminophylline 25 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionAmpicillin sodium 50 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionCaffeine 5 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionCefotaxime sodium 200 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionCimetidine hydrochloride 150 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionClindamycin phosphate 150 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionDexamethasone sodium phosphate 4 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionDobutamine hydrochloride 12,5 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionDopamine hydrochloride 80 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionEpinephrine hydrochloride 1000 µg/ml + Glucose 5%
Compatible 5 mg/ml + injectionFentanyl citrate 50 µg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionFurosemide 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionGentamicin sulfate 10 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionHeparin sodium 10 UI/ml + Glucose 5%
Incompatible 5 mg/ml + injectionIndomethacin sodium trihydrate 1 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionInsulin 100 UI/ml + Glucose 5%
Incompatible 5 mg/ml + injectionInsulin 1 UI/ml + Glucose 5%
Compatible 5 mg/ml + injectionIsoprenaline hydrochloride 0,2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionLidocaine hydrochloride 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionLorazepam 2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMorphine sulfate 4 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionNitroglycerin 5 mg/ml + Glucose 5%
Incompatible 5 mg/ml + injectionNitroprusside sodium 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionOxacillin sodium 167 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPancuronium bromide 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPenicillin G sodium 0.5 MUI/ml + Glucose 5%
Compatible 5 mg/ml + injectionPhenobarbital sodium 130 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPhenylephrine hydrochloride 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionSodium bicarbonate 42 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionVancomycin hydrochloride 50 mg/ml + Glucose 5%
injectionLidocaine hydrochloride Local anesthetic
Compatible 10 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionLorazepam Anxiolytic
Compatible 2 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 4 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionNitroprusside sodium Vasodilator
Incompatible 10 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionOxacillin sodium Antibiotic
Compatible 167 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionPancuronium bromide Curarimimetic
Compatible 1 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionPenicillin G sodium Antibiotic
Compatible 0.5 MUI/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionPhenobarbital sodium Antiepileptic
Compatible 130 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionPhenylephrine hydrochloride Sympathomimetic
Compatible 10 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Compatible 42 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 50 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%

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