Last update :
14/12/2024
References   References 1662  
Type : Journal
Web link : http://opp.sagepub.com/cgi/content/abstract/8/1/33

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Saenz CA, Ingram DS, Ogundele AB.
Title : Compatibility screening of oxaliplatin during simulated Y-site administration with other drugs.
Reference : J Oncol Pharm Practice ; 8: 33-37. 2002

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAllopurinol sodium Antigout
Compatible 6 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionAminophylline Various
Compatible 2,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionBumetanide Diuretic
Compatible 0,04 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionBuprenorphine hydrochloride Analgesic
Compatible 0,04 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionButorphanol tartrate Analgesic
Compatible 0,04 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionCarboplatin Anticancer drug
Compatible 5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 12 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionCyclophosphamide Anticancer drug
Compatible 10 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDocetaxel Anticancer drug
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDolasetron mesylate Antiemetic
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 3,2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDoxorubicin hydrochloride Anticancer drug
Compatible 1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionDroperidol Neuroleptic
Compatible 2,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionEnalaprilate Antihypertensive
Compatible 0,1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionEpirubicin hydrochloride Anticancer drug
Compatible 0,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionEtoposide phosphate Anticancer drug
Compatible 5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionFolinate calcium Cytoprotective
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Compatible 3 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionGemcitabine hydrochloride Anticancer drug
Compatible 10 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionGranisetron hydrochloride Antiemetic
Compatible 0,05 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionHaloperidol lactate Neuroleptic
Compatible 0,2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 0,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionHydroxyzine dihydrochloride Anxiolytic
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionIfosfamide Anticancer drug
Compatible 20 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionIrinotecan Anticancer drug
Compatible 1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionLorazepam Anxiolytic
Compatible 0,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMannitol Various
Compatible 150 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMesna Cytoprotective
Compatible 10 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMethotrexate sodium Anticancer drug
Compatible 12,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMitoxantrone dihydrochloride Anticancer drug
Compatible 0,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 15 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionNalbuphine hydrochloride Antidote
Compatible 10 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionOndansetron hydrochloride Antiemetic
Compatible 1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionOxaliplatin Anticancer drug
Compatible 0,5 mg/ml + injectionAllopurinol sodium 6 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionAminophylline 2,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionBumetanide 0,04 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionBuprenorphine hydrochloride 0,04 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionButorphanol tartrate 0,04 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionCalcium gluconate 40 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionCarboplatin 5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionCyclophosphamide 10 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Incompatible 0,5 mg/ml + injectionDiazepam 5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDocetaxel 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDolasetron mesylate 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDopamine hydrochloride 3,2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDoxorubicin hydrochloride 1 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionDroperidol 2,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionEnalaprilate 0,1 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionEpirubicin hydrochloride 0,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionEtoposide phosphate 5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionFamotidine 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionFentanyl citrate 50 µg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionFolinate calcium 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionFurosemide 3 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionGemcitabine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionGranisetron hydrochloride 0,05 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionHaloperidol lactate 0,2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionHydromorphone hydrochloride 0,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionHydroxyzine dihydrochloride 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionIfosfamide 20 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionIrinotecan 1 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionLorazepam 0,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMagnesium sulfate 100 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMannitol 150 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMesna 10 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMethotrexate sodium 12,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMitoxantrone dihydrochloride 0,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionMorphine sulfate 15 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionNalbuphine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionOndansetron hydrochloride 1 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionPaclitaxel 0,6 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionPotassium chloride 100 mEq/l + Glucose 5%
Compatible 0,5 mg/ml + injectionProchlorperazine edysilate 0,5 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionPromethazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionTheophylline 4 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionTopotecan 0,1 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionVerapamil hydrochloride 1,25 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionVincristine sulfate 0,05 mg/ml + Glucose 5%
Compatible 0,5 mg/ml + injectionVinorelbine tartrate 0,1 mg/ml + Glucose 5%
injectionPaclitaxel Anticancer drug
Compatible 0,6 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 100 mEq/l + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionProchlorperazine edysilate Neuroleptic
Compatible 0,5 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionTheophylline Various
Compatible 4 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionTopotecan Anticancer drug
Compatible 0,1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionVerapamil hydrochloride Anti-arrhythmic
Compatible 1,25 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionVincristine sulfate Anticancer drug
Compatible 0,05 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%
injectionVinorelbine tartrate Anticancer drug
Compatible 0,1 mg/ml + injectionOxaliplatin 0,5 mg/ml + Glucose 5%

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