Last update :
14/12/2024
Various   Filgrastim  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Accofil Belgium, Germany, Great Britain
Biocilin Mexico
Duperan Chile
Filgen Argentina
Foltran Chile
Granulokine Greece, Italy
Hebervital Colombia
Inmunef Colombia
Leucosos Colombia
Lioplim Chile
Neupogen Austria, Belgium, Croatia, Denmark, Finland, France, Great Britain, Netherlands, Poland, Portugal, Republic of South Africa, Slovenia, Spain, Sweden, Switzerland, Turkey, United States of America
Neutromax Argentina
Neutropine Argentina
Nivestim Belgium, France, Germany, Great Britain, Netherlands, Norway
Ratiograstim Austria, Germany, Great Britain, Sweden
Tevagrastim Germany, Great Britain, Netherlands, Norway, Sweden, Switzerland
Compatibility   injection   Compatibility : Filgrastim              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Filgrastim 30 µg/ml
injection Aciclovir sodium 7 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Allopurinol sodium 3 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Amikacin sulfate 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 40 µg/ml
injection Amikacin sulfate 5 mg/ml
Glucose 5% 104
Compatible
injection Filgrastim 30 µg/ml
injection Aminophylline 2.5 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Amphotericin B 0.6 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ampicillin sodium 20 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ampicillin sodium - sulbactam sodium 20/10 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
injection Filgrastim 30 µg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Bleomycin sulfate 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Bumetanide 0.04 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Buprenorphine hydrochloride 0.04 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Butorphanol tartrate 0.04 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Calcium gluconate 40 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Carboplatin 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Carmustine 1.5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Cefazolin sodium 20 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Cefonicid sodium 20 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Cefoperazone sodium 40 mg/ml
Glucose 5% 244
Precipitation after 4 hours Incompatible
injection Filgrastim 30 µg/ml
injection Cefotaxime sodium 20 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Cefoxitin sodium 20 mg/ml
Glucose 5% 244
Subvisual incompatibility Incompatible
injection Filgrastim 30 µg/ml
injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Subvisual incompatibility Incompatible
injection Filgrastim 30 µg/ml
injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Compatible
injection Filgrastim 30 µg/ml
injection Ceftazidime 40 mg/ml
Glucose 5% 244
Chemical instability Incompatible
injection Filgrastim 40 µg/ml
injection Ceftazidime 10 mg/ml
Glucose 5% 104
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Ceftizoxime sodium 20 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Unspecified incompatibility Incompatible
injection Filgrastim
injection Ceftobiprole medocaril sodium
4650
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
injection Filgrastim 15 µg/ml
injection Ceftolozane / tazobactam 10/5 mg/ml
Glucose 5% 3828
Precipitation after 1 hour Incompatible
injection Filgrastim 30 µg/ml
injection Ceftriaxone disodium 20 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Cefuroxime sodium 20 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Chlormethine hydrochloride 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Cimetidine hydrochloride 12 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Cisplatin 1 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Clindamycin phosphate 10 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Co-trimoxazole 0.8/4 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Cyclophosphamide 10 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Cytarabine 50 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Dacarbazine 4 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Dactinomycin 10 µg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Daunorubicin hydrochloride 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Dexamethasone sodium phosphate 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Diphenhydramine hydrochloride 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Doxorubicin hydrochloride 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Doxycycline hyclate 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Droperidol 0.4 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Enalaprilate 0.1 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Etoposide 0.4 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Famotidine 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Floxuridine 3 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Fluconazole 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 40 µg/ml
injection Fluconazole 2 mg/ml
Glucose 5% 104
Compatible
injection Filgrastim 30 µg/ml
injection Fludarabine phosphate 1 mg/ml
Glucose 5% 244
Unspecified incompatibility Incompatible
injection Filgrastim
injection Fluorouracil
3474
Precipitation after 1 hour Incompatible
injection Filgrastim 30 µg/ml
injection Fluorouracil 16 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Folinate calcium 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 15 µg/ml
injection Fosfomycin 30 mg/ml
Glucose 5% 4055
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Furosemide 3 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Gallium nitrate 0.4 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ganciclovir sodium 20 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Gentamicin sulfate 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 40 µg/ml
injection Gentamicin sulfate 1.6 mg/ml
Glucose 5% 104
Compatible
injection Filgrastim 30 µg/ml
injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
injection Filgrastim 30 µg/ml
injection Haloperidol lactate 0.2 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Heparin sodium 100 UI/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Hydroxyzine dihydrochloride 4 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Idarubicin hydrochloride 0.5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ifosfamide 25 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Imipenem - cilastatin sodium 10 mg/ml
Glucose 5% 244
Chemical instability Incompatible
injection Filgrastim 40 µg/ml
injection Imipenem - cilastatin sodium 5/5 mg/ml
Glucose 5% 104
Turbidity in 15 minutes Incompatible
injection Filgrastim 15 µg/ml
injection Isavuconazonium sulfate 1.5 mg/ml
Glucose 5% 3829
Compatible
injection Filgrastim 30 µg/ml
injection Lorazepam 0.1 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Mannitol 150 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Melphalan 0.1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Mesna 10 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Methotrexate sodium 15 mg/ml
Glucose 5% 244
Immediate turbidity Incompatible
injection Filgrastim 30 µg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Metoclopramide hydrochloride 5 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Metronidazole 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Minocycline hydrochloride 0.2 mg/ml
Glucose 5% 244
Color change after 1 hour Incompatible
injection Filgrastim 30 µg/ml
injection Mitomycin 0.5 mg/ml
Glucose 5% 244
Chemical instability Incompatible
injection Filgrastim
injection Mitomycin
3128
Compatible
injection Filgrastim 30 µg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 244
Unspecified incompatibility Incompatible
injection Filgrastim
Sodium chloride 0,9% 3618
Unspecified incompatibility Incompatible
injection Filgrastim
injection Mitomycin
4471
Compatible
injection Filgrastim 30 µg/ml
injection Mitoxantrone dihydrochloride 0.5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Nalbuphine hydrochloride 10 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Netilmicin sulfate 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ondansetron hydrochloride 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Pethidine hydrochloride 4 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Piperacillin sodium 40 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 3 µg/ml
injection Posaconazole 1,2 mg/ml
Sodium chloride 0,9% 4521
Compatible
injection Filgrastim
injection Posaconazole
4380
Compatible
injection Filgrastim 30 µg/ml
injection Potassium chloride 100 mEq/l
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Prochlorperazine edysilate 0.5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Promethazine hydrochloride 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ranitidine hydrochloride 2 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Sodium bicarbonate 84 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Streptozocin 40 mg/ml
Glucose 5% 244
Immediate precipitation Incompatible
injection Filgrastim 30 µg/ml
injection Thiotepa 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Ticarcillin / clavulanic acid 31 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 40 µg/ml
injection Tobramycin sulfate 1.6 mg/ml
Glucose 5% 104
Compatible
injection Filgrastim 30 µg/ml
injection Tobramycin sulfate 5 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Vancomycin hydrochloride 10 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Vinblastine sulfate 0.12 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Vincristine sulfate 0.05 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Vinorelbine tartrate 1 mg/ml
Glucose 5% 244
Compatible
injection Filgrastim 30 µg/ml
injection Zidovudine 4 mg/ml
Glucose 5% 244

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