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Antibiotic   Amoxicillin sodium / clavulanic acid  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Aktil Hungary
Amoclan Saudi Arabia
Amoklavin Turkey
Amoksiklav Poland
Amoxclav Saudi Arabia
Amplamox Brazil
Augmentin Austria, Belgium, Chile, Ecuador, France, Great Britain, Greece, Italy, Netherlands, Poland, Saudi Arabia, Spain, Switzerland, Turkey, United Arab Emirates
Betamox Portugal
Clavamox Austria
Clavicin Malaysia, Venezuela
Clavulin Brazil
Co-amoxi Switzerland
Co-Amoxicillin Switzerland
Curam New Zealand, Saudi Arabia
Darzitil Argentina
Dibional Argentina
Julmentin United Arab Emirates
Novamox Brazil
Sulbamox Chile
Tarometin Poland
Trifamox Argentina, Colombia, Ecuador, Mexico
References   injection   References : Amoxicillin sodium / clavulanic acid  
Type Publication
186 Journal Swart EL, Mooren RAG, Van Loenen AC.
Compatibility of midazolam hydrochloride and lorazepam with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1995 ; 52: 2020-2022.
889 Journal Janknegt R, Stratermans T, Cilissen J, Lohman JJHM, Hooymans PM.
Ofloxacin intravenous. Compatibility with other antibacterial agents.
Pharm Weekbl [Sci] 1991 ; 13: 207-209.
1318 Journal Ashwin J, Lynn B, Taskis CB.
Stability and administration of intravenous Augmentin.
Pharm J 1987 ; 238: 116-118.
1357 Journal Janknegt R, Schrouff GGM, Hooymans PM, Hermens WJHH, Lohman JJHM.
Quinolones and penicillins incompatibility.
Ann Pharmacotherapy 1989 ; 23: 91-92.
1746 Journal Kambia N, Merite N, Dine T, Dupin-Spriet T, Gressier B, Luyckx M, Watinne C, Brunet C.
Stability studies of amoxicillin/clavulanic acid combinaison in polyolefin infusion bags.
EJHP 2010 ; 16, 30-37.
2139 Journal Serrurier C, Chenot ED, Vigneron J, May I, Demor? B.
Assessment of injectable drug’s administration in two intensive care units and determination of potential physico-chemical incompatibilities.
EJHP Science 2006 ; 12,5: 96-99.
2231 Journal de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S.
Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.
J Antimicrob Chemother 2008 ; 61, 2: 382-388.
3520 Manufacturer Cidomycin - Summary of product Chracteristics.
Sanofi 2011
3529 Manufacturer Ciprofloxacin – Summary of Product Characteristics
Hospira 2013
3545 Manufacturer Amoxicilline / acide clavulanique - Résumé des caractéristiques du produit
Mylan SAS 2009
3549 Manufacturer Amikacine B Braun - Résumé des caractéristiques du produit.
B Braun 2012
3643 Manufacturer Gentamicin sulphate (Cidomycin®) - Summary of Product Characteristics
Sanofi 2015
3674 Manufacturer Erythromycin lactobionate - Summary of Product Characteristics
PanPharma 2016
3791 Poster Sadou Yaye H, Burtet E, Hamel C, Aljhni R, Gard C, Tilleul P.
Étude de la compatibilité physico-chimique du phloroglucinol injectable durant les mélanges au sein des tubulures en Y.
Apifh Congress, Paris November 2014 2014
3824 Journal Boudi S, Roy H, Forest JM, Leclair G.
Compatibilité physique de l'association amoxicilline-acide clavulanique en injection avec plusieurs autres médicaments lors d'une administration en Y.
Pharmactuel 2023 2023;56,3:91-98
3948 Journal Bouchoud L, Fonzo-Christe C, Klingm?ller M, Bonnabry P .
Compatibility of Intravenous Medications With Parenteral Nutrition - In Vitro Evaluation.
JPEN 2012 ;30. 416?424.
4470 Journal Claeysoone K, Basma V, Hens R, Van Bambeke F, de Jongh R, Tulkens P.
Continuous versus intermittent infusion of temocillin in intensive care unit patient.
Critical care 2005 ; 9(Suppl 1) P37
4524 Poster Stucki C, Sautter A-M, Bonnabry P.
Physical compatibility of the propofol emulsion with 33 drugs used in anaesthesiology.
ESCP Symposium, Geneva, Switzerland 2009
4654 Poster Sicard G, Donnette M, Martin N, Gensollen S, Pourroy B, Fanciullino R.
Compatibilité visuelle du Vyxeos® lors d'administration en Y avec une sélection de médicaments injectables.
Communication personnelle 2021
  Mentions Légales