Last update :
19/11/2024
Anticancer drug   Gemcitabine hydrochloride  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Accogem Mexico
Antoril Argentina
Axigem Germany
Bendacitabin Germany
Binoptos Mexico
Celzar Peru
Dercin Romania
Dhacibine Malaysia
Emcitab Colombia
Eriogem Argentina, Ecuador
Fotinex Argentina, Peru
Gebina Argentina
Gebitan Colombia
Gembio Argentina, Chile, Ecuador
Gemcimira Chile, Peru
Gemcit Portugal
Gemcitabin Germany
Gemcitac Chile
Gemko Turkey
Gemsibin Turkey
Gemsol Austria
Gemtero Chile, Peru
Gemzar Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, Croatia, Denmark, Ecuador, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Iran, Ireland, Italy, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, New Zealand, Norway, Poland, Portugal, Republic of South Africa, Romania, Slovenia, Spain, Sweden, Switzerland, Thailand, Tunisia, Turkey, United Arab Emirates, United States of America, Venezuela
Gentabin Colombia
Haxanit Argentina, Peru
Lenfotabin Mexico
Compatibility   injection   Compatibility : Gemcitabine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Precipitation after 1 hour Incompatible
injection Gemcitabine hydrochloride 16 >> 20 mg/ml
NaHCO3 3262
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Aciclovir sodium 7 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Amifostine 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Amikacin sulfate 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Aminophylline 2.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 5 mg/ml
injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Amphotericin B 0.6 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ampicillin sodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ampicillin sodium - sulbactam sodium 20/10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Aztreonam 40 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Bleomycin sulfate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Bumetanide 0.04 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Buprenorphine hydrochloride 0.04 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Butorphanol tartrate 0.04 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Calcium gluconate 40 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Carboplatin 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Carmustine 1.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cefazolin sodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cefonicid sodium 20 mg/ml
Sodium chloride 0,9% 1423
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cefoperazone sodium 40 mg/ml
Sodium chloride 0,9% 1423
Turbidity in one hour Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cefotaxime sodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cefoxitin sodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ceftazidime 40 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ceftizoxime sodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ceftriaxone disodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cefuroxime sodium 30 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Chlorpromazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cimetidine hydrochloride 12 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ciprofloxacin lactate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cisplatin 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Clindamycin phosphate 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Co-trimoxazole 0.8/4 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cyclophosphamide 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Cytarabine 50 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Dactinomycin 10 µg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Daunorubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Dexamethasone sodium phosphate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Dexrazoxane hydrochloride 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Diphenhydramine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Dobutamine hydrochloride 4 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Docetaxel 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Dopamine hydrochloride 3.2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Doxorubicin hydrochloride 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Doxycycline hyclate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Droperidol 0.4 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Enalaprilate 0.1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Etoposide 0.4 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Etoposide phosphate 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Famotidine 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Floxuridine 3 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Fludarabine phosphate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Fluorouracil 16 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Folinate calcium 2 mg/ml
Sodium chloride 0,9% 1423
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Furosemide 3 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Gallium nitrate 0.4 mg/ml
Sodium chloride 0,9% 1423
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ganciclovir sodium 20 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Gentamicin sulfate 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Haloperidol lactate 0.2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Heparin sodium 100 UI/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Hydroxyzine dihydrochloride 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Idarubicin hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ifosfamide 25 mg/ml
Sodium chloride 0,9% 1423
Color change after 1 hour Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Imipenem - cilastatin sodium 10 mg/ml
Sodium chloride 0,9% 1423
Immediate turbidity Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Irinotecan 5 mg/ml
Sodium chloride 0,9% 1423
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Lorazepam 0.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Mannitol 150 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Mesna 10 mg/ml
Sodium chloride 0,9% 1423
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Methotrexate sodium 15 mg/ml
Sodium chloride 0,9% 1423
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Methylprednisolone sodium succinate 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Metoclopramide hydrochloride 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Metronidazole 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Minocycline hydrochloride 0.2 mg/ml
Sodium chloride 0,9% 1423
Color change after 1 hour Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Mitomycin 0.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Mitoxantrone dihydrochloride 0.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Morphine sulfate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Nalbuphine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Netilmicin sulfate 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ofloxacin 4 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Paclitaxel 1.2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 16 mg/ml
injection Paclitaxel albumin 5 mg/ml
Sodium chloride 0,9% 4310
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Palonosetron hydrochloride 50 µg/ml
Glucose 5% 2009
Immediate precipitation Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Pethidine hydrochloride 4 mg/ml
Sodium chloride 0,9% 1423
Immediate turbidity Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Piperacillin sodium 40 mg/ml
Sodium chloride 0,9% 1423
Immediate turbidity Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Potassium chloride 100 mEq/l
Sodium chloride 0,9% 1423
Immediate turbidity Incompatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Prochlorperazine edysilate 0.5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Promethazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ranitidine hydrochloride 2 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Sodium bicarbonate 84 mg/ml
Sodium chloride 0,9% 1423
Precipitation after 1 hour Incompatible
injection Gemcitabine hydrochloride 16 >> 20 mg/ml
injection Sodium bicarbonate 84 mg/ml
Sodium chloride 0,9% 3262
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Streptozocin 40 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Teniposide 0.1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Thiotepa 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Ticarcillin / clavulanic acid 31 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Tobramycin sulfate 5 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Topotecan 0.1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Vancomycin hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Vinblastine sulfate 0.12 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Vincristine sulfate 0.05 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Gemcitabine hydrochloride 10 mg/ml
injection Zidovudine 4 mg/ml
Sodium chloride 0,9% 1423

  Mentions Légales