Last update :
27/11/2024
Antimuscarinic   Atropine sulfate  
injection
aerosol Eye-drops Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Atropen United States of America
Atropi S Italy
Atropin Denmark, Finland, Iceland, Norway, Sweden, Turkey, Venezuela
Atropina Argentina, Colombia, Ecuador, Italy, Portugal, Spain, Venezuela
Atropina sulfato Chile, Colombia, Ecuador, Italy, Peru
Atropine Australia, Canada, France, Great Britain, Greece, Ireland, Morocco, New Zealand, Saudi Arabia, Tunisia
Atropine sulf ES Saudi Arabia
Atropine sulphate Egypt, Ireland, Malaysia, Saudi Arabia
Atropinesulfate Belgium, Canada, Egypt, Luxembourg, Malaysia, New Zealand, United Arab Emirates, United States of America
Atropinsulfat Austria, Germany, Luxembourg, Switzerland
Atropinum sulfuricum Austria, Germany, Hungary, Poland, Switzerland
Atropion Brazil
Atropisa Brazil, Chile, Ecuador, Mexico
Dicatro Iran
Endatropina Argentina
Klonatropina Argentina
Minijet Atropine Great Britain
Stellatropine Belgium
Sulfat de atropina Romania
Sulfato de atropina Argentina, Ecuador
Compatibility   injection   Compatibility : Atropine sulfate              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Atropine sulfate 0,4 mg/ml
injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Compatible
injection Atropine sulfate 0,4 mg/ml
injection Bivalirudin 5 mg/ml
NaCl 0,9% or Glucose 5% 1944
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Atropine sulfate 0.13 & 0.17 mg/ml
injection Cimetidine hydrochloride 85.7 & 100 mg/ml
None 1203
Chemical instability Incompatible
injection Atropine sulfate
injection Cisplatin
3578
Compatible
injection Atropine sulfate 0.1 mg/ml
injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 1041
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Etomidate 2 mg/ml
None 319
Compatible
injection Atropine sulfate 0,4 mg/ml
Ringer’s lactate solution 4603
Compatible
injection Atropine sulfate 0,4 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Compatible
injection Atropine sulfate 0,4 mg/ml
injection Argatroban 1 mg/ml
Sodium chloride 0,9% 1964
Unspecified incompatibility Incompatible
injection Atropine sulfate
injection Calcium gluconate
3644
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Atropine sulfate 0,017 mg/ml
injection Dobutamine hydrochloride 0,17 mg/ml
Sodium chloride 0,9% 1221
Compatible
injection Atropine sulfate 0,4 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
injection Atropine sulfate
injection Eptifibatide
3934
Compatible
injection Atropine sulfate 0.1 mg/ml
injection Famotidine 0.2 mg/ml
Glucose 5% 398
Compatible
injection Atropine sulfate 0.1 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Fentanyl citrate 25 µg/ml
Glucose 5% 1974
Compatible
injection Atropine sulfate 0,06 mg/ml
injection Furosemide 1 mg/ml
Water for Injection 1232
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Heparin sodium 1 UI/ml
Ringer’s lactate solution 1228
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Heparin sodium 1 UI/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Ringer’s lactate solution 1228
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 1974
Chemical instability Incompatible
injection Atropine sulfate
injection Hydroxocobalamin
3932
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Ketamine hydrochloride 50 mg/ml
2109
Compatible
injection Atropine sulfate 0.04 mg/ml
injection Meropenem 1 & 20 mg/ml
Sodium chloride 0,9% 266
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Meropenem 1 & 50 mg/ml
Sodium chloride 0,9% 266
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Methadone hydrochloride 1 mg/ml
Glucose 5% 1974
Compatible
injection Atropine sulfate 0.2 mg/ml
injection Midazolam hydrochloride 2.5 mg/ml
None 404
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Morphine hydrochloride 2.5 >> 15 mg/ml
Water for Injection 1757
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Compatible
injection Atropine sulfate 0.4 mg/ml
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Nafcillin sodium 33 mg/ml
Sodium chloride 0,9% 1366
Compatible
injection Atropine sulfate 0,2 & 0,5 mg/ml
injection Nalbuphine hydrochloride 5 & 10 mg/ml
616
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
injection Atropine sulfate 0.04 mg/ml
injection Netilmicin sulfate 3 mg/ml
NaCl 0,9% or Glucose 5% 1200
Compatible
injection Atropine sulfate 0.133 mg/ml
injection Ondansetron hydrochloride 1.33 mg/ml
Sodium chloride 0,9% 815
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Palonosetron hydrochloride 50 µg/ml
Glucose 5% 2279
Unspecified incompatibility Incompatible
injection Atropine sulfate
injection Pantoprazole sodium
2090
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Paracetamol 10 mg/ml
4742
Precipitation after 24 hours Incompatible
injection Atropine sulfate 0.17 mg/ml
injection Pentobarbital sodium 28.6 mg/ml
None 1203
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Compatible
injection Atropine sulfate 0.5 mg/ml
injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Compatible
injection Atropine sulfate 0.1 mg/ml
injection Propofol 10 mg/ml
None 300
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Propofol 2 mg/ml
None 319
Compatible
injection Atropine sulfate 0,4 mg/ml
injection Ranitidine hydrochloride 25 mg/ml
None 58
Compatible
injection Atropine sulfate 1 mg/ml
injection Sugammadex 100 mg/ml
None 3372
Compatible
injection Atropine sulfate 0.4 mg/ml
injection Thiopental sodium 25 mg/ml
Water for Injection 319
Compatible
injection Atropine sulfate 0,4 & 1 mg/ml
injection Tirofiban 50 µg/ml
NaCl 0,9% or Glucose 5% 1603
Compatible
injection Atropine sulfate
injection Tirofiban
1512
Compatible
injection Atropine sulfate 0.0008 mg/ml
injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057

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