Monographie - Phytomenadione - Stabilis 4.0

Last update :
28/04/2024

Vitamin

Phytomenadione

Injection

Oral solution

Stability in solutions

Stability of mixtures

Factors which affect stability

Compatibility

Route of administration

References

Pdf

Chemical structure

Tradename

Tradename

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Adcokion	Egypt
Amidalak	Mexico
Amri-K	Egypt
Aquamephyton	United States of America
Epikavit	Egypt
Haemokion	Egypt
Hyvit	Brazil
Kanakion	Brazil, Portugal
Kavit	Brazil
Kenadion	India
Kisan	Malaysia
Konakion	Argentina, Austria, Belgium, Chile, Colombia, Croatia, Denmark, Ecuador, Egypt, Finland, Germany, Great Britain, Greece, Hungary, Iceland, Ireland, Italy, Luxembourg, Morocco, Netherlands, New Zealand, Norway, Poland, Saudi Arabia, Spain, Sweden, Switzerland, Turkey, United Arab Emirates
Oskavit	Iran
Rupek	Argentina
Vikadic	Iran
Vitatron	Brazil

References

Injection

References : Phytomenadione

	Type	Publication
397	Journal	Fong PA, Ward J. Visual compatibility of intravenous famotidine with selected drugs. Am J Hosp Pharm 1989 ; 46: 125-126.
951	Journal	Ho PC, Wong VK. Influence of DL methionine and sodium metasulphite on the photostability of vitamin K1. PDA J Pharm Sci Technol 1998 ; 52: 129-133.
1200	Journal	Chaudry IA, Bruey KP, Hurlburt LE, Oden EM. Compatibility of netilmycin sulfate injection with commonly used intravenous injections and additives. Am J Hosp Pharm 1981 ; 38: 1737-1742.
1201	Journal	Yuhas EM, Lofton FT, Rosenberg HA, Mayron D, Baldinus JG. Cimetidine hydrochloride compatibility III: Room temperature stability in drug admixtures. Am J Hosp Pharm 1981 ; 38: 1919-1922.
2231	Journal	de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S. Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection. J Antimicrob Chemother 2008 ; 61, 2: 382-388.
3128	Manufacturer	Mitomycine (Amétycine®) - Résumé Caractéristiques du Produit Prostrakan 2013
3372	Journal	Hanci V, Ali Kiraz H, Ömür D, Ekin S, Uyan B, Yurtlu B.S. Precipitation in Gallipoli: Sugammadex / Amiodarone & Sugammadex / Dobutamine & Sugammadex / Protamine. Rev Bras Anestesiol 2013 ; 63, 1: 163-166.
3985	Poster	Manai M., Soussi M.A., Lazreg O., Drira C., Ben Tekaya S. et Razgallah Khrouf M. Compatibilité physique entre médicaments injectables et nutrition parentérale pédiatrique : Evaluation in-vitro. Hopipharm Congress 2017 - Nancy 2017
4471	Manufacturer	Amétycine 10 mg poudre pour solution injectable - Résumé des caractéristiques du produit - Oct 10, 2019 Kyowa Kirin Pharma 2019
4698	Journal	Ayari G, D'Huart E, Vigneron J, Demoré B. Y-site compatibility of intravenous medications commonly used in intensive care units : laboratory tests on 75 mixtures involving nine main drugs. Pharmaceutical Technology in Hospital Pharmacy 2022

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