Last update :
03/05/2024
References   References 4419  
Type : Journal
Web link : https://doi.org/10.5863/1551-6776-13.3.156

Research teams :
Authors : Holt R.J, Siegert S.W.K, Krishna A.
Title : Physical Compatibility of Ibuprofen Lysine Injection with Selected Drugs During Simulated Y-site Injection.
Reference : J Pediatr Pharmacol Ther ; 13, 3: 155-161. 2008

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAmikacin sulfate Antibiotic
Incompatible 50 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 250 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionCaffeine citrate Respiratory stimulant
Incompatible 20 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionCeftazidime Antibiotic
Compatible 200 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionDobutamine hydrochloride Cardiotonic
Incompatible 1 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 8 >> 100 µg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionFurosemide Diuretic
Compatible 10 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Compatible 10 UI/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionIbuprofen lysinate Anti-inflammatory
Incompatible 10 mg/ml + Parenteral nutrition (with lipids)
Incompatible 10 mg/ml + InjectionAmikacin sulfate 50 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionAmikacin sulfate 250 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionCaffeine citrate 20 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionCeftazidime 200 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionDobutamine hydrochloride 1 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionEpinephrine hydrochloride 8 >> 100 µg/ml + Water for Injection
Compatible 10 mg/ml + InjectionFurosemide 10 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionHeparin sodium 100 UI/ml + Water for Injection
Compatible 10 mg/ml + InjectionHeparin sodium 10 UI/ml + Water for Injection
Compatible 10 mg/ml + InjectionInsulin 1 UI/ml + Water for Injection
Compatible 10 mg/ml + InjectionInsulin 0.1 UI/ml + Water for Injection
Incompatible 10 mg/ml + InjectionMidazolam hydrochloride 1 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionMorphine sulfate 0.5 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionMorphine sulfate 50 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionPhenobarbital sodium 130 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionPhenobarbital sodium 30 mg/ml + Water for Injection
Compatible 10 mg/ml + InjectionPotassium chloride 2 mEq/l + Water for Injection
Compatible 10 mg/ml + InjectionSodium bicarbonate 84 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionVancomycin hydrochloride 50 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionVecuronium bromide 1 mg/ml + Water for Injection
Incompatible 10 mg/ml + InjectionVecuronium bromide 2 mg/ml + Water for Injection
InjectionInsulin Glucose-lowering
Compatible 1 UI/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Compatible 0.1 UI/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 1 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 5 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionMorphine sulfate Analgesic
Compatible 0.5 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 50 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionPhenobarbital sodium Antiepileptic
Compatible 130 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Compatible 30 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionPotassium chloride Electrolyte
Compatible 2 mEq/l + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionVancomycin hydrochloride Antibiotic
Incompatible 50 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
InjectionVecuronium bromide Curarimimetic
Incompatible 1 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 2 mg/ml + InjectionIbuprofen lysinate 10 mg/ml + Water for Injection

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