Last update :
19/11/2024
References   References 4419  
Type : Journal
Web link : https://doi.org/10.5863/1551-6776-13.3.156

Research teams :
Authors : Holt R.J, Siegert S.W.K, Krishna A.
Title : Physical Compatibility of Ibuprofen Lysine Injection with Selected Drugs During Simulated Y-site Injection.
Reference : J Pediatr Pharmacol Ther ; 13, 3: 155-161. 2008

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmikacin sulfate Antibiotic
Incompatible 50 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 250 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionCaffeine citrate Respiratory stimulant
Incompatible 20 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionCeftazidime Antibiotic
Compatible 200 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionDobutamine hydrochloride Cardiotonic
Incompatible 1 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 8 >> 100 µg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionFurosemide Diuretic
Compatible 10 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Compatible 10 UI/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionIbuprofen lysinate Anti-inflammatory
Incompatible 10 mg/ml + Parenteral nutrition (with lipids)
Incompatible 10 mg/ml + injectionAmikacin sulfate 50 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionAmikacin sulfate 250 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionCaffeine citrate 20 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionCeftazidime 200 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionDobutamine hydrochloride 1 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionEpinephrine hydrochloride 8 >> 100 µg/ml + Water for Injection
Compatible 10 mg/ml + injectionFurosemide 10 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionHeparin sodium 100 UI/ml + Water for Injection
Compatible 10 mg/ml + injectionHeparin sodium 10 UI/ml + Water for Injection
Compatible 10 mg/ml + injectionInsulin 1 UI/ml + Water for Injection
Compatible 10 mg/ml + injectionInsulin 0.1 UI/ml + Water for Injection
Incompatible 10 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionMorphine sulfate 0.5 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionMorphine sulfate 50 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionPhenobarbital sodium 130 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionPhenobarbital sodium 30 mg/ml + Water for Injection
Compatible 10 mg/ml + injectionPotassium chloride 2 mEq/l + Water for Injection
Compatible 10 mg/ml + injectionSodium bicarbonate 84 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionVancomycin hydrochloride 50 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionVecuronium bromide 1 mg/ml + Water for Injection
Incompatible 10 mg/ml + injectionVecuronium bromide 2 mg/ml + Water for Injection
injectionInsulin Glucose-lowering
Compatible 1 UI/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Compatible 0.1 UI/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionMidazolam hydrochloride Anxiolytic
Incompatible 1 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 5 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionMorphine sulfate Analgesic
Compatible 0.5 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 50 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionPhenobarbital sodium Antiepileptic
Compatible 130 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Compatible 30 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionPotassium chloride Electrolyte
Compatible 2 mEq/l + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionVancomycin hydrochloride Antibiotic
Incompatible 50 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
injectionVecuronium bromide Curarimimetic
Incompatible 1 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection
Incompatible 2 mg/ml + injectionIbuprofen lysinate 10 mg/ml + Water for Injection

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