Last update :
19/11/2024
References   References 405  
Type : Journal

Research teams : Boston - Brigham and women\'s hospital
Authors : Nieves-Cordero AL, Luciw HM, Souney PF.
Title : Compatibility of narcotic analgesic solutions with various antibiotics during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 42: 1108-1109. 1985

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionCefalotin sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCefamandole nafate Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionCefoperazone sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Incompatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCeforanide Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCefotaxime sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCefoxitin sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCeftizoxime sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 30 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 30 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionChloramphenicol sodium succinate Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionClindamycin phosphate Antibiotic
Compatible 12 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 12 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 12 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionCo-trimoxazole Antibiotic
Compatible 4/0.8 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 4/0.8 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 4/0.8 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionDoxycycline hyclate Antibiotic
Compatible 1 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 0.8 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 0.2 mg/ml + injectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefalotin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefamandole nafate 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefoperazone sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCeforanide 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionChloramphenicol sodium succinate 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionClindamycin phosphate 12 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionGentamicin sulfate 0.8 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionKanamycin sulfate 2.5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + injectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMoxalactam 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionNafcillin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionOxacillin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionPenicillin G potassium 0.1 MUI/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionPiperacillin sodium 60 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionTobramycin sulfate 0.8 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
injectionKanamycin sulfate Antibiotic
Compatible 2.5 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 2.5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 2.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMinocycline hydrochloride Antibiotic
Incompatible 0.2 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefalotin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefamandole nafate 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefoperazone sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCeforanide 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionChloramphenicol sodium succinate 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionClindamycin phosphate 12 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionGentamicin sulfate 0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionKanamycin sulfate 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMoxalactam 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionNafcillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionOxacillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPenicillin G potassium 0.1 MUI/ml + Glucose 5%
Compatible 1 mg/ml + injectionPiperacillin sodium 60 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionTobramycin sulfate 0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
injectionMoxalactam Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionNafcillin sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionOxacillin sodium Antibiotic
Compatible 20 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionPenicillin G potassium Antibiotic
Compatible 0.1 MUI/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.1 MUI/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.1 MUI/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + injectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCefalotin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCefamandole nafate 20 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionCefoperazone sodium 20 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionCefoperazone sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCeforanide 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionChloramphenicol sodium succinate 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionClindamycin phosphate 12 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionGentamicin sulfate 0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionKanamycin sulfate 2.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionMoxalactam 20 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionNafcillin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionOxacillin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionPenicillin G potassium 0.1 MUI/ml + Glucose 5%
Compatible 10 mg/ml + injectionPiperacillin sodium 60 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionTobramycin sulfate 0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
injectionPiperacillin sodium Antibiotic
Compatible 60 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 60 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 60 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 0.8 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + injectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%

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