Last update :
19/11/2024
References   References 3823  
Type : Journal
Web link : http://www.pharmactuel.com/index.php/pharmactuel/article/view/264/779

Research teams : Palma de Mallorca - Hôpital Universitari Son Espases
Authors : Juan E.P, Palau M.M, Cerd? S.A, Rubert M.A, Nicolau B.R.
Title : Compatibilité physique de médicaments administrés dans l’unité de soins intensifs
Reference : Pharmactuel ; 48, 3 : 146-152. 2015

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmiodarone hydrochloride Anti-arrhythmic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 15 mg/ml + NaHCO3
Compatible 15 mg/ml + injectionCisatracurium besylate 5 mg/ml + Glucose 5%
Compatible 15 mg/ml + injectionDobutamine hydrochloride 10 mg/ml + Glucose 5%
Compatible 15 mg/ml + injectionDopamine hydrochloride 20 mg/ml + Glucose 5%
Compatible 15 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 15 mg/ml + injectionFurosemide 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 15 mg/ml + injectionHeparin sodium 500 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionInsulin 2 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionLabetalol hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionNimodipine 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%
Compatible 15 mg/ml + injectionNorepinephrine bitartrate 0.96 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 15 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Incompatible 15 mg/ml + injectionThiopental sodium 60 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionTirofiban 250 µg/ml + NaCl 0,9% or Glucose 5%
Compatible 15 mg/ml + injectionUrapidil 5 mg/ml + Glucose 5%
injectionCisatracurium besylate Curarimimetic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionClonazepam 0.2 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Incompatible 5 mg/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Incompatible 5 mg/ml + NaHCO3
Incompatible 5 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Incompatible 5 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionOmeprazole sodium 1.6 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionPotassium chloride 10 mEq/l + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionRemifentanil hydrochloride 100 µg/ml + Sodium chloride 0,9%
Incompatible 5 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
injectionClonazepam Antiepileptic
Compatible 0.2 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 0,2 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionClonidine hydrochloride Antihypertensive
Compatible 0.012 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 0.012 mg/ml + injectionClonazepam 0.2 mg/ml + Sodium chloride 0,9%
Compatible 0.012 mg/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Compatible 0.012 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 0.012 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 0.012 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 0.012 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionDiclofenac Anti-inflammatory
Incompatible 3 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 3 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Compatible 3 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 3 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Incompatible 3 mg/ml + injectionMidazolam hydrochloride 2,1 mg/ml + Sodium chloride 0,9%
Compatible 3 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 3 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
injectionDobutamine hydrochloride Cardiotonic
Compatible 10 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDopamine hydrochloride 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionNorepinephrine bitartrate 0.96 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 20 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionDobutamine hydrochloride 10 mg/ml + Glucose 5%
Compatible 20 mg/ml + injectionNorepinephrine bitartrate 0.96 mg/ml + Glucose 5%
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 10 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Incompatible 10 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionLabetalol hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 10 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionTirofiban 250 µg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 10 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Incompatible 10 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Incompatible 10 mg/ml + injectionHaloperidol lactate 0,5 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionMannitol 200 mg/ml + Sodium chloride 0,9%
Incompatible 10 mg/ml + injectionMidazolam hydrochloride 2,1 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 10 mg/ml + injectionOmeprazole sodium 1.6 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Incompatible 10 mg/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
injectionHaloperidol lactate Neuroleptic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 0,5 mg/ml + NaHCO3
Compatible 0.5 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.5 mg/ml + injectionClonazepam 0.2 mg/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Incompatible 0,5 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0,5 mg/ml + injectionOmeprazole sodium 1,6 mg/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionRemifentanil hydrochloride 100 µg/ml + Sodium chloride 0,9%
Incompatible 0.5 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 0.5 mg/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
Incompatible 0,5 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Incompatible 500 UI/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 500 UI/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Incompatible 500 UI/ml + injectionLabetalol hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 500 UI/ml + injectionPotassium chloride 10 mEq/l + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionRemifentanil hydrochloride 100 µg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionTirofiban 250 µg/ml + Sodium chloride 0,9%
Compatible 500 UI/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
injectionInsulin Glucose-lowering
Compatible 2 UI/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 UI/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2 UI/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionTirofiban 250 µg/ml + Sodium chloride 0,9%
Compatible 2 UI/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
injectionLabetalol hydrochloride Beta-blocker
Compatible 4 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 4 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Incompatible 4 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 4 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 4 mg/ml + injectionTirofiban 250 µg/ml + Sodium chloride 0,9%
Compatible 4 mg/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
injectionMannitol Various
Compatible 200 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Incompatible 200 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 200 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionMidazolam hydrochloride Anxiolytic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 2,1 mg/ml + NaHCO3
Compatible 2.1 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 2.1 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionClonazepam 0.2 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Incompatible 2,1 mg/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Incompatible 2,1 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 2,1 mg/ml + injectionOmeprazole sodium 1,6 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionPotassium chloride 10 mEq/l + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionRemifentanil hydrochloride 100 µg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionRocuronium bromide 10 mg/ml + Sodium chloride 0,9%
Incompatible 2.1 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Incompatible 2,1 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 2.1 mg/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
Incompatible 2,1 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionNimodipine Antihypertensive
Compatible 0.2 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionClonazepam 0.2 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 0.2 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Incompatible 0,2 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionNitroglycerin Vasodilator
Compatible 0.2 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionCisatracurium besylate 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionFurosemide 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionHeparin sodium 500 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionInsulin 2 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionLabetalol hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionPotassium chloride 10 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionThiopental sodium 60 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionTirofiban 250 µg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.2 mg/ml + injectionUrapidil 5 mg/ml + NaCl 0,9% or Glucose 5%
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.96 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.96 mg/ml + injectionDobutamine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.96 mg/ml + injectionDopamine hydrochloride 20 mg/ml + Glucose 5%
injectionOmeprazole sodium Proton pump inhibitor
Compatible 1.6 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 1.6 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Incompatible 1,6 mg/ml + injectionHaloperidol lactate 0,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,6 mg/ml + injectionMidazolam hydrochloride 2,1 mg/ml + Sodium chloride 0,9%
injectionPotassium chloride Electrolyte
Compatible 10 mEq/l + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 10 mEq/l + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 10 mEq/l + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 10 mEq/l + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 10 mEq/l + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
injectionRemifentanil hydrochloride Analgesic
Compatible 100 µg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Compatible 100 µg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 100 µg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 100 µg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 100 µg/ml + injectionRocuronium bromide 10 mg/ml + Sodium chloride 0,9%
injectionRocuronium bromide Curarimimetic
Compatible 10 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 10 mg/ml + injectionRemifentanil hydrochloride 100 µg/ml + Sodium chloride 0,9%
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + Glucose 5%
Compatible 84 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Incompatible 84 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Incompatible 84 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionNitroglycerin 0.2 mg/ml + Glucose 5%
Compatible 84 mg/ml + injectionPotassium chloride 10 mEq/l + Sodium chloride 0,9%
Incompatible 84 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 84 mg/ml + injectionUrapidil 5 mg/ml + None
injectionThiopental sodium General anesthetic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 60 mg/ml + NaHCO3
Incompatible 60 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 60 mg/ml + injectionCisatracurium besylate 5 mg/ml + Sodium chloride 0,9%
Incompatible 60 mg/ml + injectionClonazepam 0,2 mg/ml + Sodium chloride 0,9%
Compatible 60 mg/ml + injectionDiclofenac 3 mg/ml + Sodium chloride 0,9%
Compatible 60 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 60 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Incompatible 60 mg/ml + injectionMannitol 200 mg/ml + Sodium chloride 0,9%
Incompatible 60 mg/ml + injectionMidazolam hydrochloride 2,1 mg/ml + Sodium chloride 0,9%
Compatible 60 mg/ml + injectionNimodipine 0.2 mg/ml + Sodium chloride 0,9%
Compatible 60 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 60 mg/ml + injectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Compatible 60 mg/ml + injectionValproic acid 16 mg/ml + Sodium chloride 0,9%
injectionTirofiban Anticoagulant
Compatible 250 µg/ml + injectionAmiodarone hydrochloride 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 250 µg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 250 µg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 250 µg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Compatible 250 µg/ml + injectionLabetalol hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 250 µg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 250 µg/ml + injectionUrapidil 5 mg/ml + Sodium chloride 0,9%
injectionUrapidil Antihypertensive
Compatible 5 mg/ml + injectionAmiodarone hydrochloride 15 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Incompatible 5 mg/ml + injectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionHaloperidol lactate 0.5 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionHeparin sodium 500 UI/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionInsulin 2 UI/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionLabetalol hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionMidazolam hydrochloride 2.1 mg/ml + Sodium chloride 0,9%
Compatible 5 mg/ml + injectionNitroglycerin 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 5 mg/ml + injectionSodium bicarbonate 84 mg/ml + None
Compatible 5 mg/ml + injectionTirofiban 250 µg/ml + Sodium chloride 0,9%
injectionValproic acid Antiepileptic
Compatible 16 mg/ml + injectionClonazepam 0.2 mg/ml + Sodium chloride 0,9%
Compatible 16 mg/ml + injectionClonidine hydrochloride 0.012 mg/ml + Sodium chloride 0,9%
Incompatible 16 mg/ml + injectionHaloperidol lactate 0,5 mg/ml + Sodium chloride 0,9%
Compatible 16 mg/ml + injectionMannitol 200 mg/ml + Sodium chloride 0,9%
Incompatible 16 mg/ml + injectionMidazolam hydrochloride 2,1 mg/ml + Sodium chloride 0,9%
Incompatible 16 mg/ml + injectionNimodipine 0,2 mg/ml + Sodium chloride 0,9%
Compatible 16 mg/ml + injectionThiopental sodium 60 mg/ml + Sodium chloride 0,9%

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