Last update :
28/04/2024
References   References 319  
Type : Journal

Research teams : Chapel Hill - University of North Carolina Hospital, Department of Pharmacy
Authors : Hadzija BW, Lubarsky DA.
Title : Compatibility of etomidate, thiopental sodium, and propofol injections with drugs commonly administered during induction of anesthesia.
Reference : Am J Health-Syst Pharm ; 52: 997-999. 1995

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAlfentanil hydrochloride Analgesic
Compatible 500 µg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 500 µg/ml + InjectionPropofol 2 mg/ml + None
Compatible 500 µg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionAscorbic acid Vitamin
Incompatible 500 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 500 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 500 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionAtracurium besylate Curarimimetic
Compatible 10 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 10 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 10 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 0.4 mg/ml + InjectionPropofol 2 mg/ml + None
Compatible 0.4 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionEphedrine hydrochloride Sympathomimetic
Compatible 50 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 50 mg/ml + InjectionPropofol 2 mg/ml + None
InjectionEphedrine sulfate Sympathomimetic
Incompatible 50 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionEtomidate General anesthetic
Compatible 2 mg/ml + InjectionAlfentanil hydrochloride 500 µg/ml + None
Incompatible 2 mg/ml + InjectionAscorbic acid 500 mg/ml + None
Compatible 2 mg/ml + InjectionAtracurium besylate 10 mg/ml + None
Compatible 2 mg/ml + InjectionAtropine sulfate 0.4 mg/ml + None
Compatible 2 mg/ml + InjectionEphedrine hydrochloride 50 mg/ml + None
Compatible 2 mg/ml + InjectionFentanyl citrate 50 µg/ml + None
Compatible 2 mg/ml + InjectionLidocaine hydrochloride 20 mg/ml + None
Compatible 2 mg/ml + InjectionLorazepam 2 mg/ml + None
Compatible 2 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml + None
Compatible 2 mg/ml + InjectionMivacurium 2 mg/ml + None
Compatible 2 mg/ml + InjectionMorphine sulfate 10 mg/ml + None
Compatible 2 mg/ml + InjectionPancuronium bromide 2 mg/ml + None
Compatible 2 mg/ml + InjectionPhenylephrine hydrochloride 10 mg/ml + None
Compatible 2 mg/ml + InjectionSufentanil citrate 0.05 mg/ml + None
Compatible 2 mg/ml + InjectionSuxamethonium chloride 20 mg/ml + None
Incompatible 2 mg/ml + InjectionVecuronium bromide 1 mg/ml + None
InjectionFentanyl citrate Analgesic
Compatible 50 µg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 50 µg/ml + InjectionPropofol 2 mg/ml + None
Compatible 50 µg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionLidocaine hydrochloride Local anesthetic
Compatible 20 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 20 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 20 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionLorazepam Anxiolytic
Compatible 2 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 2 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 2 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 5 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 5 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionMivacurium Curarimimetic
Compatible 2 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 2 mg/ml + InjectionPropofol 2 mg/ml + None
Compatible 2 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionMorphine sulfate Analgesic
Compatible 10 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 10 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 10 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionPancuronium bromide Curarimimetic
Compatible 2 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 2 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 2 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionPhenylephrine hydrochloride Sympathomimetic
Compatible 10 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 10 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 10 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionPropofol General anesthetic
Compatible 2 mg/ml + InjectionAlfentanil hydrochloride 500 µg/ml + None
Compatible 2 mg/ml + InjectionAscorbic acid 500 mg/ml + None
Compatible 2 mg/ml + InjectionAtracurium besylate 10 mg/ml + None
Compatible 2 mg/ml + InjectionAtropine sulfate 0.4 mg/ml + None
Compatible 2 mg/ml + InjectionEphedrine hydrochloride 50 mg/ml + None
Compatible 2 mg/ml + InjectionFentanyl citrate 50 µg/ml + None
Compatible 2 mg/ml + InjectionLidocaine hydrochloride 20 mg/ml + None
Compatible 2 mg/ml + InjectionLorazepam 2 mg/ml + None
Compatible 2 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml + None
Compatible 2 mg/ml + InjectionMivacurium 2 mg/ml + None
Compatible 2 mg/ml + InjectionMorphine sulfate 10 mg/ml + None
Compatible 2 mg/ml + InjectionPancuronium bromide 2 mg/ml + None
Compatible 2 mg/ml + InjectionPhenylephrine hydrochloride 10 mg/ml + None
Compatible 2 mg/ml + InjectionSufentanil citrate 0.05 mg/ml + None
Compatible 2 mg/ml + InjectionSuxamethonium chloride 20 mg/ml + None
Compatible 2 mg/ml + InjectionVecuronium bromide 1 mg/ml + None
InjectionSufentanil citrate Analgesic
Compatible 0.05 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 0.05 mg/ml + InjectionPropofol 2 mg/ml + None
Compatible 0.05 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionSuxamethonium chloride Curarimimetic
Compatible 20 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 20 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 20 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection
InjectionThiopental sodium General anesthetic
Compatible 25 mg/ml + InjectionAlfentanil hydrochloride 500 µg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionAscorbic acid 500 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionAtracurium besylate 10 mg/ml + Water for Injection
Compatible 25 mg/ml + InjectionAtropine sulfate 0.4 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionEphedrine sulfate 50 mg/ml + Water for Injection
Compatible 25 mg/ml + InjectionFentanyl citrate 50 µg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionLidocaine hydrochloride 20 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionLorazepam 2 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml + Water for Injection
Compatible 25 mg/ml + InjectionMivacurium 2 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionMorphine sulfate 10 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionPancuronium bromide 2 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionPhenylephrine hydrochloride 10 mg/ml + Water for Injection
Compatible 25 mg/ml + InjectionSufentanil citrate 0.05 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionSuxamethonium chloride 20 mg/ml + Water for Injection
Incompatible 25 mg/ml + InjectionVecuronium bromide 1 mg/ml + Water for Injection
InjectionVecuronium bromide Curarimimetic
Incompatible 1 mg/ml + InjectionEtomidate 2 mg/ml + None
Compatible 1 mg/ml + InjectionPropofol 2 mg/ml + None
Incompatible 1 mg/ml + InjectionThiopental sodium 25 mg/ml + Water for Injection

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