Last update :
19/11/2024
References   References 319  
Type : Journal

Research teams : Chapel Hill - University of North Carolina Hospital, Department of Pharmacy
Authors : Hadzija BW, Lubarsky DA.
Title : Compatibility of etomidate, thiopental sodium, and propofol injections with drugs commonly administered during induction of anesthesia.
Reference : Am J Health-Syst Pharm ; 52: 997-999. 1995

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAlfentanil hydrochloride Analgesic
Compatible 500 µg/ml + injectionEtomidate 2 mg/ml + None
Compatible 500 µg/ml + injectionPropofol 2 mg/ml + None
Compatible 500 µg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionAscorbic acid Vitamin
Incompatible 500 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 500 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 500 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionAtracurium besylate Curarimimetic
Compatible 10 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 10 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 0.4 mg/ml + injectionPropofol 2 mg/ml + None
Compatible 0.4 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionEphedrine hydrochloride Sympathomimetic
Compatible 50 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 50 mg/ml + injectionPropofol 2 mg/ml + None
injectionEphedrine sulfate Sympathomimetic
Incompatible 50 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionEtomidate General anesthetic
Compatible 2 mg/ml + injectionAlfentanil hydrochloride 500 µg/ml + None
Incompatible 2 mg/ml + injectionAscorbic acid 500 mg/ml + None
Compatible 2 mg/ml + injectionAtracurium besylate 10 mg/ml + None
Compatible 2 mg/ml + injectionAtropine sulfate 0.4 mg/ml + None
Compatible 2 mg/ml + injectionEphedrine hydrochloride 50 mg/ml + None
Compatible 2 mg/ml + injectionFentanyl citrate 50 µg/ml + None
Compatible 2 mg/ml + injectionLidocaine hydrochloride 20 mg/ml + None
Compatible 2 mg/ml + injectionLorazepam 2 mg/ml + None
Compatible 2 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + None
Compatible 2 mg/ml + injectionMivacurium 2 mg/ml + None
Compatible 2 mg/ml + injectionMorphine sulfate 10 mg/ml + None
Compatible 2 mg/ml + injectionPancuronium bromide 2 mg/ml + None
Compatible 2 mg/ml + injectionPhenylephrine hydrochloride 10 mg/ml + None
Compatible 2 mg/ml + injectionSufentanil citrate 0.05 mg/ml + None
Compatible 2 mg/ml + injectionSuxamethonium chloride 20 mg/ml + None
Incompatible 2 mg/ml + injectionVecuronium bromide 1 mg/ml + None
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionEtomidate 2 mg/ml + None
Compatible 50 µg/ml + injectionPropofol 2 mg/ml + None
Compatible 50 µg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionLidocaine hydrochloride Local anesthetic
Compatible 20 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 20 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 20 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionLorazepam Anxiolytic
Compatible 2 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 2 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 2 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 5 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 5 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionMivacurium Curarimimetic
Compatible 2 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 2 mg/ml + injectionPropofol 2 mg/ml + None
Compatible 2 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionMorphine sulfate Analgesic
Compatible 10 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 10 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionPancuronium bromide Curarimimetic
Compatible 2 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 2 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 2 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionPhenylephrine hydrochloride Sympathomimetic
Compatible 10 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 10 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 10 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionPropofol General anesthetic
Compatible 2 mg/ml + injectionAlfentanil hydrochloride 500 µg/ml + None
Compatible 2 mg/ml + injectionAscorbic acid 500 mg/ml + None
Compatible 2 mg/ml + injectionAtracurium besylate 10 mg/ml + None
Compatible 2 mg/ml + injectionAtropine sulfate 0.4 mg/ml + None
Compatible 2 mg/ml + injectionEphedrine hydrochloride 50 mg/ml + None
Compatible 2 mg/ml + injectionFentanyl citrate 50 µg/ml + None
Compatible 2 mg/ml + injectionLidocaine hydrochloride 20 mg/ml + None
Compatible 2 mg/ml + injectionLorazepam 2 mg/ml + None
Compatible 2 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + None
Compatible 2 mg/ml + injectionMivacurium 2 mg/ml + None
Compatible 2 mg/ml + injectionMorphine sulfate 10 mg/ml + None
Compatible 2 mg/ml + injectionPancuronium bromide 2 mg/ml + None
Compatible 2 mg/ml + injectionPhenylephrine hydrochloride 10 mg/ml + None
Compatible 2 mg/ml + injectionSufentanil citrate 0.05 mg/ml + None
Compatible 2 mg/ml + injectionSuxamethonium chloride 20 mg/ml + None
Compatible 2 mg/ml + injectionVecuronium bromide 1 mg/ml + None
injectionSufentanil citrate Analgesic
Compatible 0.05 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 0.05 mg/ml + injectionPropofol 2 mg/ml + None
Compatible 0.05 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionSuxamethonium chloride Curarimimetic
Compatible 20 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 20 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 20 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection
injectionThiopental sodium General anesthetic
Compatible 25 mg/ml + injectionAlfentanil hydrochloride 500 µg/ml + Water for Injection
Incompatible 25 mg/ml + injectionAscorbic acid 500 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionAtracurium besylate 10 mg/ml + Water for Injection
Compatible 25 mg/ml + injectionAtropine sulfate 0.4 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionEphedrine sulfate 50 mg/ml + Water for Injection
Compatible 25 mg/ml + injectionFentanyl citrate 50 µg/ml + Water for Injection
Incompatible 25 mg/ml + injectionLidocaine hydrochloride 20 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionLorazepam 2 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + Water for Injection
Compatible 25 mg/ml + injectionMivacurium 2 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionMorphine sulfate 10 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionPancuronium bromide 2 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionPhenylephrine hydrochloride 10 mg/ml + Water for Injection
Compatible 25 mg/ml + injectionSufentanil citrate 0.05 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionSuxamethonium chloride 20 mg/ml + Water for Injection
Incompatible 25 mg/ml + injectionVecuronium bromide 1 mg/ml + Water for Injection
injectionVecuronium bromide Curarimimetic
Incompatible 1 mg/ml + injectionEtomidate 2 mg/ml + None
Compatible 1 mg/ml + injectionPropofol 2 mg/ml + None
Incompatible 1 mg/ml + injectionThiopental sodium 25 mg/ml + Water for Injection

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