Last update :
18/07/2024
References   References 248  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Martinez JF.
Title : Turbidimetric assessment of the compatibility of taxol with 42 other drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 50: 300-304. 1993

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Compatible 7 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionAminophylline Various
Compatible 2.5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionAmphotericin B Antifungal
Incompatible 0.6 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 20/10 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionBleomycin sulfate Anticancer drug
Compatible 1 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionButorphanol tartrate Analgesic
Compatible 0.04 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionCalcium chloride Electrolyte
Compatible 20 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionCeforanide Antibiotic
Compatible 20 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Compatible 40 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionChlorpromazine hydrochloride Anxiolytic
Incompatible 2 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionDacarbazine Anticancer drug
Compatible 4 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionDroperidol Neuroleptic
Compatible 0.4 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 2 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionFloxuridine Anticancer drug
Compatible 3 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Compatible 3 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionGanciclovir sodium Antiviral
Compatible 20 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionHydroxyzine dihydrochloride Anxiolytic
Incompatible 4 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionIfosfamide Anticancer drug
Compatible 25 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionMannitol Various
Compatible 150 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionMesna Cytoprotective
Compatible 10 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionMitoxantrone dihydrochloride Anticancer drug
Incompatible 0.5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionNalbuphine hydrochloride Antidote
Compatible 10 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionOndansetron hydrochloride Antiemetic
Compatible 0.5 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionPaclitaxel Anticancer drug
Compatible 1.2 mg/ml + injectionAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionAminophylline 2.5 mg/ml + Glucose 5%
Incompatible 1.2 mg/ml + injectionAmphotericin B 0.6 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionAmpicillin sodium - sulbactam sodium 20/10 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionBleomycin sulfate 1 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionButorphanol tartrate 0.04 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionCalcium chloride 20 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionCeforanide 20 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionCeftazidime 40 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionCeftriaxone disodium 20 mg/ml + Glucose 5%
Incompatible 1.2 mg/ml + injectionChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionDacarbazine 4 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionDroperidol 0.4 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionFamotidine 2 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionFloxuridine 3 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionFluconazole 2 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionFurosemide 3 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Incompatible 1.2 mg/ml + injectionHydroxyzine dihydrochloride 4 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionIfosfamide 25 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionMagnesium sulfate 100 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionMannitol 150 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionMesna 10 mg/ml + Glucose 5%
Incompatible 1.2 mg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Incompatible 1.2 mg/ml + injectionMitoxantrone dihydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionNalbuphine hydrochloride 10 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionOndansetron hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionPentostatin 0.4 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionPethidine hydrochloride 4 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionPotassium chloride 100 mEq/l + Glucose 5%
Compatible 1.2 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionVinblastine sulfate 0.12 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionVincristine sulfate 0.05 mg/ml + Glucose 5%
Compatible 1.2 mg/ml + injectionZidovudine 4 mg/ml + Glucose 5%
injectionPentostatin Anticancer drug
Compatible 0.4 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionPethidine hydrochloride Analgesic
Compatible 4 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 100 mEq/l + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionVinblastine sulfate Anticancer drug
Compatible 0.12 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionVincristine sulfate Anticancer drug
Compatible 0.05 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%
injectionZidovudine Antiviral
Compatible 4 mg/ml + injectionPaclitaxel 1.2 mg/ml + Glucose 5%

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