Ultimele actualizari :
19/11/2024
Bibliografie   Bibliografie 1506  
tip : ziar
Internet legătură într- : http://dx.doi.org/10.1136/ejhpharm-2014-000539

Echipe de cercetare : Barcelone - Hopital Clinic of Barcelona
Autor : Lopez-Cabezas C, Guerrero L, Molas G, Anglada H, Soy D.
titlu : Physicochemical compatibility of high concentration drugs usually Y-site administered in intensive care units.
Référence : EJHP ;22:107-112. 2015

Nivelul dovezii : 
Nivel de evidență B+
stabilitatea fizică : 
Examinare vizuala Turbidimetrie 
Stabilitate chimică : 
Cromatografia de lichide de inalta performanta cu detector in ultraviolet
Stabilitate definită ca si 95% din concentrația inițială
alte metode : 
Măsurarea PH-ului 
Comentarii : 

Listele
InjectabilClonidine hydrochloride Antihipertensiv
Compatibil 0.0075 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.0075 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.0075 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + clorura de sodiu 0,9%
Compatibil 0.0075 mg/ml + InjectabilFurosemide 2 mg/ml + clorura de sodiu 0,9%
Compatibil 0.0075 mg/ml + InjectabilHeparin sodium 50 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.0075 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.0075 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.0075 mg/ml + InjectabilMorphine hydrochloride 1 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.0075 mg/ml + InjectabilPantoprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilDobutamine hydrochloride Cardiotonic
Compatibil 8 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Incompatibil 8 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilFentanyl citrate 30 µg/ml + NaCl 0,9% sau Glucoza 5%
Incompatibil 8 mg/ml + InjectabilFurosemide 2 mg/ml + clorura de sodiu 0,9%
Compatibil 8 mg/ml + InjectabilFurosemide 2 mg/ml + Glucoza 5%
Compatibil 8 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + Glucoza 5%
Incompatibil 8 mg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + clorura de sodiu 0,9%
Compatibil 8 mg/ml + InjectabilMorphine hydrochloride 1 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilDopamine hydrochloride Cardiotonic
Compatibil 8 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Incompatibil 8 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilFentanyl citrate 30 µg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilFurosemide 2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilMorphine hydrochloride 1 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 8 mg/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilEpinephrine hydrochloride Simpatomimetic
Compatibil 40 µg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilEsomeprazole sodium Inhibitor al pompei de protoni
Compatibil 0.32 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + clorura de sodiu 0,9%
Incompatibil 0.32 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Incompatibil 0.32 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilEpinephrine hydrochloride 40 µg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilFentanyl citrate 30 µg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilFlumazenil 0.04 mg/ml + clorura de sodiu 0,9%
Compatibil 0.32 mg/ml + InjectabilFurosemide 2 mg/ml + clorura de sodiu 0,9%
Compatibil 0.32 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Incompatibil 0.32 mg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilMorphine hydrochloride 1 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilFentanyl citrate Antialgic
Compatibil 30 µg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 30 µg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 30 µg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 30 µg/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 30 µg/ml + InjectabilPantoprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilFlumazenil Antidot
Compatibil 0.04 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + clorura de sodiu 0,9%
InjectabilFurosemide Diuretic
Compatibil 2 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + clorura de sodiu 0,9%
Incompatibil 2 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + clorura de sodiu 0,9%
Compatibil 2 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + Glucoza 5%
Compatibil 2 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 2 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + clorura de sodiu 0,9%
Compatibil 2 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilHeparin sodium Anticoagulant
Compatibil 50 UI/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 50 UI/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilInsulin Hipoglicemiant
Compatibil 1 UI/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 UI/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 UI/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 UI/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 UI/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 UI/ml + InjectabilMidazolam hydrochloride 4 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 UI/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilMethadone hydrochloride Antialgic
Compatibil 0.2 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilFurosemide 2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilHeparin sodium 50 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.2 mg/ml + InjectabilPantoprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilMidazolam hydrochloride Anxiolitic
Compatibil 4 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + Glucoza 5%
Incompatibil 4 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + clorura de sodiu 0,9%
Compatibil 4 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Incompatibil 4 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 4 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 4 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 4 mg/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 4 mg/ml + InjectabilRemifentanil hydrochloride 20 µg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilMorphine hydrochloride Antialgic
Compatibil 1 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 mg/ml + InjectabilEsomeprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 1 mg/ml + InjectabilNorepinephrine bitartrate 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilNorepinephrine bitartrate Simpatomimetic
Compatibil 0.32 mg/ml + InjectabilDobutamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilDopamine hydrochloride 8 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilFentanyl citrate 30 µg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilInsulin 1 UI/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilMorphine hydrochloride 1 mg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilPantoprazole sodium Inhibitor al pompei de protoni
Compatibil 0.32 mg/ml + InjectabilClonidine hydrochloride 0.0075 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilFentanyl citrate 30 µg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilMethadone hydrochloride 0.2 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 0.32 mg/ml + InjectabilRemifentanil hydrochloride 20 µg/ml + NaCl 0,9% sau Glucoza 5%
InjectabilRemifentanil hydrochloride Antialgic
Compatibil 20 µg/ml + InjectabilMidazolam hydrochloride 4 mg/ml + NaCl 0,9% sau Glucoza 5%
Compatibil 20 µg/ml + InjectabilPantoprazole sodium 0.32 mg/ml + NaCl 0,9% sau Glucoza 5%
Stabilitatea in amestec
polipropilen NaCl 0,9% sau Glucoza 5% 22-25°C Ferit de lumina
Injectabil Dopamine hydrochloride 8 mg/ml
Injectabil Dobutamine hydrochloride 8 mg/ml
24 Ora
polipropilen NaCl 0,9% sau Glucoza 5% 22-25°C Ferit de lumina
Injectabil Dopamine hydrochloride 8 mg/ml
Injectabil Methadone hydrochloride 0.2 mg/ml
24 Ora
polipropilen NaCl 0,9% sau Glucoza 5% 22-25°C Ferit de lumina
Injectabil Dobutamine hydrochloride 8 mg/ml
Injectabil Methadone hydrochloride 0.2 mg/ml
24 Ora
polipropilen NaCl 0,9% sau Glucoza 5% 22-25°C Ferit de lumina
Injectabil Pantoprazole sodium 0.32 mg/ml
Injectabil Methadone hydrochloride 0.2 mg/ml
24 Ora
polipropilen NaCl 0,9% sau Glucoza 5% 22-25°C Ferit de lumina
Injectabil Midazolam hydrochloride 4 mg/ml
Injectabil Methadone hydrochloride 0.2 mg/ml
24 Ora
polipropilen clorura de sodiu 0,9% 22-25°C Ferit de lumina
Injectabil Esomeprazole sodium 0.32 mg/ml
Injectabil Methadone hydrochloride 0.2 mg/ml
24 Ora
polipropilen Glucoza 5% 22-25°C Ferit de lumina
Injectabil Dobutamine hydrochloride 8 mg/ml
Injectabil Midazolam hydrochloride 4 mg/ml
24 Ora

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