Last update :
08/11/2024
References   References 1974  
Type : Journal
Web link : https://www.sciencedirect.com/science/article/pii/0885392496001273

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Chandler SW, Trissel LA, Weinstein SM
Title : Combined administration of opoids with selected drugs to manage pain and other cancer symptoms initial safety screening for compatibility.
Reference : J Pain Symptom Manage ; 12, 3: 168-171. 1996

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionDiazepam Anxiolytic
Compatible 0.5 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 2 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 2 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 25 µg/ml + injectionAtropine sulfate 0.4 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionDiazepam 0.5 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionHydroxyzine dihydrochloride 4 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionKetorolac tromethamine 1 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionLorazepam 0.1 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionMidazolam hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionPhenobarbital sodium 2 mg/ml + Glucose 5%
Incompatible 25 µg/ml + injectionPhenytoin sodium 2 mg/ml + Glucose 5%
Compatible 25 µg/ml + injectionScopolamine hydrobromide 0.05 mg/ml + Glucose 5%
injectionHaloperidol lactate Neuroleptic
Compatible 0.2 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + injectionAtropine sulfate 0.4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDiazepam 0.5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionHydroxyzine dihydrochloride 4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionKetorolac tromethamine 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionLorazepam 0.1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMidazolam hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPhenobarbital sodium 2 mg/ml + Glucose 5%
Incompatible 0.5 mg/ml + injectionPhenytoin sodium 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionScopolamine hydrobromide 0.05 mg/ml + Glucose 5%
injectionHydroxyzine dihydrochloride Anxiolytic
Compatible 4 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 4 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 4 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 4 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionKetorolac tromethamine Anti-inflammatory
Compatible 1 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionLorazepam Anxiolytic
Compatible 0.1 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 0.1 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.1 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionMethadone hydrochloride Analgesic
Compatible 1 mg/ml + injectionAtropine sulfate 0.4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDiazepam 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHydroxyzine dihydrochloride 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionKetorolac tromethamine 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionLorazepam 0.1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMidazolam hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPhenobarbital sodium 2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionPhenytoin sodium 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionScopolamine hydrobromide 0.05 mg/ml + Glucose 5%
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 5 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 0.2 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionAtropine sulfate 0.4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDiazepam 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHydroxyzine dihydrochloride 4 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionKetorolac tromethamine 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionLorazepam 0.1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMidazolam hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPhenobarbital sodium 2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionPhenytoin sodium 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionScopolamine hydrobromide 0.05 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionScopolamine hydrobromide 0.05 mg/ml + Glucose 5%
injectionPhenobarbital sodium Antiepileptic
Compatible 2 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 2 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 2 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 2 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Incompatible 2 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Incompatible 2 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Incompatible 2 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
injectionScopolamine hydrobromide Antimuscarinic
Compatible 0.05 mg/ml + injectionFentanyl citrate 25 µg/ml + Glucose 5%
Compatible 0.05 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + injectionMethadone hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%

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