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Proton pump inhibitor   Esomeprazole sodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers
Adptor Mexico
Axagon Italy
Axiago Sweden
Cativa Sweden
Cronopep Colombia, Peru
Eliprot Ecuador
Emune Ecuador
Epral Chile
Esio Ecuador
Esmonat India, Turkey
Esoblok Turkey
Esofax Ecuador
Esolium Peru
Esomep Switzerland
Esomeprazol Chile, Colombia, Ecuador, Romania, Spain
Esomeprazole United States of America
Esopral Italy, Sweden
Esopran Peru
Esoton Plus Peru
Esoz Colombia, India
Ezole Peru
Gletop Venezuela
Inexium France
Milenium Ecuador
Nexiam Belgium, Luxembourg
Nexium Argentina, Chile, Colombia, Ecuador, Egypt, Germany, Great Britain, Greece, Iceland, Ireland, Italy, Malaysia, Mexico, Norway, Portugal, Romania, Saudi Arabia, Spain, Sweden, Switzerland, Turkey, United Arab Emirates, United States of America, Venezuela
Redica Sweden
Refexxin Sweden
Compatibility   injection   Compatibility : Esomeprazole sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Color change Incompatible
injection Esomeprazole sodium 0.8 mg/ml
Parenteral nutrition (binary mixture) 3948
Compatible
injection Esomeprazole sodium 0.4 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Unspecified incompatibility Incompatible
injection Esomeprazole sodium
injection Ceftobiprole medocaril sodium
4650
Color change Incompatible
injection Esomeprazole sodium 0,8 mg/ml
Parenteral nutrition (with lipids) 3948
Immediate precipitation Incompatible
injection Esomeprazole sodium 0.8 mg/ml
injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
injection Esomeprazole sodium 0,4 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
injection Esomeprazole sodium 0,4 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Immediate precipitation Incompatible
injection Esomeprazole sodium 0.4 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Compatible
injection Esomeprazole sodium 0.8 mg/ml
injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
injection Esomeprazole sodium 0,4 mg/ml
injection Cisatracurium besylate 1 mg/ml
Sodium chloride 0,9% 3429
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Clonidine hydrochloride 0.0075 mg/ml
Sodium chloride 0,9% 1506
Color change after 4 hours Incompatible
injection Esomeprazole sodium 0.32 mg/ml
injection Dobutamine hydrochloride 8 mg/ml
NaCl 0,9% or Glucose 5% 1506
Color change after 4 hours Incompatible
injection Esomeprazole sodium 0.32 mg/ml
injection Dopamine hydrochloride 8 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Esomeprazole sodium 0,4 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Epinephrine hydrochloride 40 µg/ml
NaCl 0,9% or Glucose 5% 1506
Color change Incompatible
injection Esomeprazole sodium 0,8 mg/ml
injection Esmolol hydrochloride 10 mg/ml
Sodium chloride 0,9% 3879
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Fentanyl citrate 30 µg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Flumazenil 0.04 mg/ml
Sodium chloride 0,9% 1506
Turbidity in 2 hours Incompatible
injection Esomeprazole sodium 0.8 mg/ml
injection Fosfomycin 30 mg/ml
Sodium chloride 0,9% 4055
Compatible
injection Esomeprazole sodium 0.8 mg/ml
injection Fosfomycin 30 mg/ml
Glucose 5% 4055
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Furosemide 2 mg/ml
Sodium chloride 0,9% 1506
Compatible
injection Esomeprazole sodium 0,8 mg/ml
injection Hydrocortisone sodium succinate 1 mg/ml
Sodium chloride 0,9% 4465
Compatible
injection Esomeprazole sodium 0,8 mg/ml
injection Imipenem-Cilastatin / Relebactam 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Insulin 1 UI/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Esomeprazole sodium 1 mg/ml
injection Insulin aspart 1 UI/ml
Sodium chloride 0,9% 1508
Unspecified incompatibility Incompatible
injection Esomeprazole sodium 1 mg/ml
injection Insulin aspart 1 UI/ml
Glucose 5% 1508
Immediate turbidity Incompatible
injection Esomeprazole sodium 0.8 mg/ml
injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Color change Incompatible
injection Esomeprazole sodium 0,8 mg/ml
injection Labetalol hydrochloride 5 mg/ml
Sodium chloride 0,9% 3879
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Methadone hydrochloride 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Esomeprazole sodium 0.8 mg/ml
injection Metoprolol tartrate 0.4 mg/ml
Sodium chloride 0,9% 3879
Immediate turbidity Incompatible
injection Esomeprazole sodium 0.32 mg/ml
injection Midazolam hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
injection Esomeprazole sodium 0.32 mg/ml
injection Morphine hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1506
Immediate precipitation Incompatible
injection Esomeprazole sodium 0.04 mg/ml
injection Nefopam 0.08 mg/ml
2311
Turbidity in one hour Incompatible
injection Esomeprazole sodium 0,8 mg/ml
injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
injection Esomeprazole sodium 40 mg/ml
injection Sugammadex 100 mg/ml
None 3372
Compatible
injection Esomeprazole sodium 0,8 mg/ml
injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Compatible
injection Esomeprazole sodium 0.8 mg/ml
injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
injection Esomeprazole sodium 0.4 mg/ml
injection Telavancin hydrochloride 7.5 mg/ml
Ringer’s lactate solution 3254
Color change after 1 hour Incompatible
injection Esomeprazole sodium 0,4 mg/ml
injection Telavancin hydrochloride 7,5 mg/ml
NaCl 0,9% or Glucose 5% 3254
Unspecified incompatibility Incompatible
injection Esomeprazole sodium
injection Tigecycline
3332
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