Last update :
23/11/2022
Analgesic   Nefopam  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acupan France, Great Britain, Ireland, Italy, Luxembourg, Morocco, North Ireland, Poland, Romania, Tunisia
Nefam Italy
Nefopam Egypt, Poland
Nephentil Mexico
Nopain Egypt
Oxadol Italy
Painstop Saudi Arabia
Compatibility   Injection   Compatibility : Nefopam              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Nefopam 0,08 mg/ml
Injection Acetylsalicylic acid lysinate 10 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Amiodarone hydrochloride 9 mg/ml
Glucose 5% 4698
Turbidity in one hour Incompatible
Injection Nefopam 0.16 mg/ml
Injection Amoxicillin sodium 20.83 mg/ml
NaCl 0,9% or Glucose 5% 4254
Immediate precipitation Incompatible
Injection Nefopam 2.5 mg/ml
Injection Blinatumomab 0.125 & 0.375 µg/ml
Sodium chloride 0,9% 3976
Compatible
Injection Nefopam 0,8 mg/ml
Injection Calcium chloride 2 mg/ml
Sodium chloride 0,9% 4698
Turbidity in one hour Incompatible
Injection Nefopam 0.16 mg/ml
Injection Cefazolin sodium 41.6 mg/ml
NaCl 0,9% or Glucose 5% 4254
Immediate turbidity Incompatible
Injection Nefopam 0,16 mg/ml
Injection Cefotaxime sodium 40 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 5 mg/ml
Injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Compatible
Injection Nefopam 2,5 mg/ml
Injection Droperidol 0,052 mg/ml
Sodium chloride 0,9% 4267
Immediate precipitation Incompatible
Injection Nefopam 0.08 mg/ml
Injection Esomeprazole sodium 0.04 mg/ml
2311
Immediate turbidity Incompatible
Injection Nefopam 1,7 mg/ml
Injection Furosemide 10 mg/ml
4698
Compatible
Injection Nefopam 0.16 mg/ml
Injection Gentamicin sulfate 4.17 mg/ml
NaCl 0,9% or Glucose 5% 4254
Immediate turbidity Incompatible
Injection Nefopam 1,7 mg/ml
Injection Heparin sodium 208,3 UI/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Hydrocortisone sodium succinate 2 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Insulin 1 UI/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Isosorbide dinitrate 1 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Magnesium sulfate 3>>4,5 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Nicardipine hydrochloride 1 mg/ml
Sodium chloride 0,9% 4698
Immediate precipitation Incompatible
Injection Nefopam 0.08 mg/ml
Injection Omeprazole sodium 0.04 mg/ml
2311
Compatible
Injection Nefopam 0.08 mg/ml
Injection Pantoprazole sodium 0.04 mg/ml
2311
Compatible
Injection Nefopam 0,5 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Immediate precipitation Incompatible
Injection Nefopam 0,2 mg/ml
Injection Posaconazole 1,2 mg/ml
Sodium chloride 0,9% 4521
Immediate precipitation Incompatible
Injection Nefopam 2,5 mg/ml
Injection Posaconazole 1,2 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Nefopam 0,16 mg/ml
Injection Pyridoxine hydrochloride 0,5 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Thiamine hydrochloride 0,5 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0,16 mg/ml
Injection Tramadol hydrochloride 6,3 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nefopam 0.16 mg/ml
Injection Vancomycin hydrochloride 31.25 mg/ml
NaCl 0,9% or Glucose 5% 4254

  Mentions Légales