Last update :
03/05/2024
Local anesthetic   Levobupivacaine hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Chirocaina Chile
Chirocaine Australia, Belgium, Brazil, Finland, Great Britain, Greece, Hungary, Ireland, Italy, Luxembourg, Malaysia, Peru, Spain, Sweden, Switzerland, Turkey, Venezuela
Levobupivacaina Spain
Levobupivacaine Belgium, France
Levocaine Peru
Compatibility   Injection   Compatibility : Levobupivacaine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Levobupivacaine hydrochloride
Injection Clonidine hydrochloride 0,0084 mg/ml
Sodium chloride 0,9% 3507
Compatible
Injection Levobupivacaine hydrochloride
Injection Fentanyl citrate 4 µg/ml
Sodium chloride 0,9% 3507
Compatible
Injection Levobupivacaine hydrochloride 1.27 mg/ml
Injection Fentanyl citrate 2 µg/ml
Sodium chloride 0,9% 2225
Compatible
Injection Levobupivacaine hydrochloride
Injection Hyaluronidase
3184
Compatible
Injection Levobupivacaine hydrochloride
Injection Morphine sulfate 0,05 mg/ml
Sodium chloride 0,9% 3507
Immediate precipitation Incompatible
Injection Levobupivacaine hydrochloride
Injection Sodium bicarbonate
3507
Compatible
Injection Levobupivacaine hydrochloride 1,25 mg/ml
Injection Sufentanil citrate 0,001 mg/ml
Sodium chloride 0,9% 1908
Compatible
Injection Levobupivacaine hydrochloride 1.25 mg/ml
Injection Sufentanil citrate 0.001 mg/ml
Sodium chloride 0,9% 1938
Compatible
Injection Levobupivacaine hydrochloride 1 mg/ml
Injection Sufentanil citrate 0.001 mg/ml
Sodium chloride 0,9% 1835
Compatible
Injection Levobupivacaine hydrochloride 1.25 mg/ml
Injection Sufentanil citrate 0.001 mg/ml
Sodium chloride 0,9% 1962
Compatible
Injection Levobupivacaine hydrochloride 1.25 mg/ml
Injection Sufentanil citrate 0.00075 mg/ml
Sodium chloride 0,9% 4522
Compatible
Injection Levobupivacaine hydrochloride 7.5 mg/ml
Injection Sugammadex 100 mg/ml
None 3372
Immediate precipitation Incompatible
Injection Levobupivacaine hydrochloride
NaHCO3 3507

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