Last update :
03/02/2023
Respiratory stimulant   Doxapram hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Caropram India
Dopram Belgium, Denmark, Finland, France, Germany, Great Britain, Greece, Iran, Ireland, Netherlands, New Zealand, Norway, United States of America
Doxapram Great Britain, United States of America
Compatibility   Injection   Compatibility : Doxapram hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Unspecified incompatibility Incompatible
Injection Doxapram hydrochloride
Injection Aminophylline
3612
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Ampicillin sodium 50 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Caffeine citrate 20 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Calcium chloride 100 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Calcium gluconate 100 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Cefazolin sodium 100 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Ceftazidime 40 mg/ml
Glucose 5% 1802
Production of gas bubbles Incompatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Clindamycin phosphate 10 mg/ml
Glucose 5% 1802
Unspecified incompatibility Incompatible
Injection Doxapram hydrochloride
Injection Dexamethasone sodium phosphate
3668
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Erythromycin lactobionate 5 mg/ml
Glucose 5% 1802
Immediate precipitation Incompatible
Injection Doxapram hydrochloride
Injection Esketamine
4700
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Fentanyl citrate 25 µg/ml
Glucose 5% 1802
Unspecified incompatibility Incompatible
Injection Doxapram hydrochloride
Injection Furosemide
3612
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Gentamicin sulfate 10 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Heparin sodium 1 UI/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Insulin 1 UI/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Metoclopramide hydrochloride 1 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Metronidazole 5 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Oxacillin sodium 20 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Phenobarbital sodium 10 mg/ml
Glucose 5% 1802
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Ranitidine hydrochloride 2 mg/ml
Glucose 5% 1802
Unspecified incompatibility Incompatible
Injection Doxapram hydrochloride
Injection Thiopental sodium
3612
Compatible
Injection Doxapram hydrochloride 2 mg/ml
Injection Vancomycin hydrochloride 5 mg/ml
Glucose 5% 1802

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