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References   References 3723  
Type : Journal

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Barb? F, Legagneur H, Boisseau D, Badonnel Y, Boutroy M.J.
Title : Stabilité des préparations extemporanées de doxapram (Doprams®) à usage néonatal.
Reference : Archives de P?diatrie ; 5, 10: 1170-1171. 1998

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Stability indicating capability inadequately assessed
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
No visual inspection
Degradation products not observed in real conditions

List of drugs
InjectionDoxapram hydrochloride Respiratory stimulant
Stability in solutions Polypropylen Syringe Glucose 5% 2.5 mg/ml 25°C Light
36 Hour
Stability in solutions Polypropylen Syringe Glucose 5% 8 mg/ml 25°C Light
24 Hour

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